SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a98'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 5a98 POLYHEDRIN
(Cypovirus
15) 		5 / 12 GLY A 152
LEU A 113
MET A 155
ILE A 151
LEU A 111
 None
 1.05A 1lhuA-5a98A:
undetectable		 1lhuA-5a98A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a98 POLYHEDRIN
(Cypovirus
15) 		4 / 6 LEU A 111
GLN A 110
LEU A 187
PHE A  53
 None
 1.00A 2einP-5a98A:
undetectable
2einW-5a98A:
undetectable		 2einP-5a98A:
21.31
2einW-5a98A:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5a98 POLYHEDRIN
(Cypovirus
15) 		4 / 6 LEU A 111
GLN A 110
LEU A 187
PHE A 189
 None
 1.09A 2einP-5a98A:
undetectable
2einW-5a98A:
undetectable		 2einP-5a98A:
21.31
2einW-5a98A:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 5a98 POLYHEDRIN
(Cypovirus
15) 		3 / 3 LEU A  29
ASN A 116
ARG A 191
 None
ATP  A 252 ( 4.5A)
None
 0.74A 2qhfA-5a98A:
undetectable		 2qhfA-5a98A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UG8_A_IMNA2001_2
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 5a98 POLYHEDRIN
(Cypovirus
15) 		3 / 3 TYR A 167
GLU A  48
TYR A  28
 None
 1.00A 3ug8A-5a98A:
undetectable		 3ug8A-5a98A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CD2_A_FOLA207_0
(DIHYDROFOLATE
REDUCTASE)		 5a98 POLYHEDRIN
(Cypovirus
15) 		5 / 12 ILE A 220
ILE A 233
PHE A 232
THR A  30
THR A  42
 None
 1.14A 4cd2A-5a98A:
undetectable		 4cd2A-5a98A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5a98 POLYHEDRIN
(Cypovirus
15) 		4 / 7 LEU A 111
GLN A 110
LEU A 187
PHE A 189
 None
 0.93A 5zcoC-5a98A:
undetectable
5zcoJ-5a98A:
undetectable		 5zcoC-5a98A:
21.31
5zcoJ-5a98A:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5a98 POLYHEDRIN
(Cypovirus
15) 		4 / 7 LEU A 111
GLN A 110
LEU A 187
PHE A 189
 None
 0.97A 5zcqC-5a98A:
undetectable
5zcqJ-5a98A:
undetectable		 5zcqC-5a98A:
21.31
5zcqJ-5a98A:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5a98 POLYHEDRIN
(Cypovirus
15) 		4 / 7 LEU A 111
GLN A 110
LEU A 187
PHE A 189
 None
 0.96A 5zcqP-5a98A:
undetectable
5zcqW-5a98A:
undetectable		 5zcqP-5a98A:
21.31
5zcqW-5a98A:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5a98 POLYHEDRIN
(Cypovirus
15) 		4 / 6 PHE A  53
LEU A 124
LEU A 187
HIS A  55
 None
 1.02A 6e43B-5a98A:
undetectable		 6e43B-5a98A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 5a98 POLYHEDRIN
(Cypovirus
15) 		4 / 6 PHE A  53
LEU A 124
LEU A 187
HIS A  55
 None
 1.02A 6e43C-5a98A:
undetectable		 6e43C-5a98A:
18.94