SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a99'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 5a99 POLYHEDRIN
(Operophtera
brumata
cypovirus
19) 		3 / 3 LEU A  37
SER A 186
ASN A  62
 None
 0.83A 1bx4A-5a99A:
undetectable		 1bx4A-5a99A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 5a99 POLYHEDRIN
(Operophtera
brumata
cypovirus
19) 		3 / 3 SER A 110
GLU A 225
ASP A 245
 None
 0.81A 2avdB-5a99A:
undetectable		 2avdB-5a99A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		 5a99 POLYHEDRIN
(Operophtera
brumata
cypovirus
19) 		4 / 6 LEU A 212
LEU A 209
ILE A  56
ARG A  55
 None
 0.97A 2rlfC-5a99A:
undetectable
2rlfD-5a99A:
undetectable		 2rlfC-5a99A:
10.50
2rlfD-5a99A:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 5a99 POLYHEDRIN
(Operophtera
brumata
cypovirus
19) 		3 / 3 ASP A  75
TRP A  63
SER A  45
 None
 0.97A 4lrhA-5a99A:
undetectable		 4lrhA-5a99A:
19.70