SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a9a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5a9a POLYHEDRIN
(Simulium
ubiquitum
cypovirus) 		4 / 8 TYR A 225
TYR A  47
GLY A 212
ILE A 215
 None
 0.90A 2zm9A-5a9aA:
undetectable		 2zm9A-5a9aA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I90_A_ACTA500_0
(1-PHOSPHATIDYLINOSIT
OL PHOSPHODIESTERASE)		 5a9a POLYHEDRIN
(Simulium
ubiquitum
cypovirus) 		3 / 3 LYS A 152
ARG A 158
TRP A 116
 None
 1.25A 4i90A-5a9aA:
undetectable		 4i90A-5a9aA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 5a9a POLYHEDRIN
(Simulium
ubiquitum
cypovirus) 		3 / 3 HIS A  95
HIS A  96
ARG A  78
 UTP  A1245 (-4.7A)
UTP  A1245 (-4.0A)
UTP  A1245 (-3.0A)
 1.14A 6b58A-5a9aA:
undetectable		 6b58A-5a9aA:
17.08