SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a9b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_1
(16S RRNA METHYLASE)		 5a9b POLYHEDRIN
(Cypovirus
1) 		3 / 3 ASP A  45
GLU A 219
SER A 102
 None
 0.78A 3p2kA-5a9bA:
undetectable		 3p2kA-5a9bA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_4_BEZ4801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5a9b POLYHEDRIN
(Cypovirus
1) 		4 / 5 PHE A  65
ARG A 209
ILE A  61
ILE A  51
 None
 1.09A 5dzk4-5a9bA:
undetectable
5dzkg-5a9bA:
undetectable
5dzkm-5a9bA:
undetectable
5dzkn-5a9bA:
undetectable		 5dzk4-5a9bA:
1.87
5dzkg-5a9bA:
19.01
5dzkm-5a9bA:
22.32
5dzkn-5a9bA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 5a9b POLYHEDRIN
(Cypovirus
1) 		5 / 12 LEU A 168
LEU A 177
MET A 124
THR A 146
ILE A 111
 None
 1.09A 5itzB-5a9bA:
undetectable		 5itzB-5a9bA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X66_A_MTXA402_1
(THYMIDYLATE SYNTHASE)		 5a9b POLYHEDRIN
(Cypovirus
1) 		5 / 12 PHE A  65
ILE A 109
GLY A 127
ASN A 128
MET A 124
 None
 1.16A 5x66A-5a9bA:
undetectable
5x66B-5a9bA:
undetectable		 5x66A-5a9bA:
20.21
5x66B-5a9bA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5a9b POLYHEDRIN
(Cypovirus
1) 		5 / 12 LEU A 168
ILE A 109
ILE A 225
TYR A 224
LEU A 220
 None
 1.04A 5y2tB-5a9bA:
undetectable		 5y2tB-5a9bA:
undetectable