SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5a9p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ADS_A_IMNA2_2 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	5a9p	POLYHEDRIN (Operophtera brumata cypovirus 18)	4 / 6	ILE A 109 ILE A 225 TYR A 224 LEU A 68	None	1.09A	3adsA-5a9pA: undetectable	3adsA-5a9pA: 21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ONN_A_ACTA271_0 (PROTEIN SSM1)	5a9p	POLYHEDRIN (Operophtera brumata cypovirus 18)	4 / 5	GLY A 88 GLU A 84 GLY A 94 PRO A 97	None	0.95A	3onnA-5a9pA: undetectable	3onnA-5a9pA: 20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O2B_B_LOCB503_2 (TUBULIN BETA-2B CHAIN)	5a9p	POLYHEDRIN (Operophtera brumata cypovirus 18)	5 / 12	LEU A 168 LEU A 177 MET A 124 THR A 146 ILE A 111	None	1.09A	4o2bB-5a9pA: undetectable	4o2bB-5a9pA: 18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ITZ_B_LOCB502_1 (TUBULIN BETA-2B CHAIN)	5a9p	POLYHEDRIN (Operophtera brumata cypovirus 18)	5 / 12	LEU A 168 LEU A 177 MET A 124 THR A 146 ILE A 111	None	1.06A	5itzB-5a9pA: undetectable	5itzB-5a9pA: 18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y2T_B_8LXB501_0 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	5a9p	POLYHEDRIN (Operophtera brumata cypovirus 18)	5 / 12	LEU A 168 ILE A 109 ILE A 225 TYR A 224 LEU A 220	None	0.92A	5y2tB-5a9pA: undetectable	5y2tB-5a9pA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3ADS_A_IMNA2_2","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","5a9p","POLYHEDRIN","Operophtera brumata cypovirus 18",4,"ILE A 109;ILE A 225;TYR A 224;LEU A  68","None","1.09A","3adsA-5a9pA:undetectable","3adsA-5a9pA:21.90"],["3ONN_A_ACTA271_0","PROTEIN SSM1","5a9p","POLYHEDRIN","Operophtera brumata cypovirus 18",4,"GLY A  88;GLU A  84;GLY A  94;PRO A  97","None","0.95A","3onnA-5a9pA:undetectable","3onnA-5a9pA:20.98"],["4O2B_B_LOCB503_2","TUBULIN BETA-2B CHAIN","5a9p","POLYHEDRIN","Operophtera brumata cypovirus 18",5,"LEU A 168;LEU A 177;MET A 124;THR A 146;ILE A 111","None","1.09A","4o2bB-5a9pA:undetectable","4o2bB-5a9pA:18.57"],["5ITZ_B_LOCB502_1","TUBULIN BETA-2B CHAIN","5a9p","POLYHEDRIN","Operophtera brumata cypovirus 18",5,"LEU A 168;LEU A 177;MET A 124;THR A 146;ILE A 111","None","1.06A","5itzB-5a9pA:undetectable","5itzB-5a9pA:18.57"],["5Y2T_B_8LXB501_0","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","5a9p","POLYHEDRIN","Operophtera brumata cypovirus 18",5,"LEU A 168;ILE A 109;ILE A 225;TYR A 224;LEU A 220","None","0.92A","5y2tB-5a9pA:undetectable","5y2tB-5a9pA:undetectable"]]