SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5abj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 5abj VP3
(Enterovirus
A) 		5 / 10 ARG C 178
VAL C  55
VAL C 117
VAL C 169
ILE C 172
 None
 1.19A 1fe2A-5abjC:
undetectable		 1fe2A-5abjC:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 5abj VP2
(Enterovirus
A) 		4 / 7 PHE B  92
PRO B  83
ALA B  96
PHE B 245
 None
 1.03A 1lqtA-5abjB:
undetectable		 1lqtA-5abjB:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 5abj VP2
(Enterovirus
A) 		4 / 7 PHE B  92
PRO B  83
ALA B  96
PHE B 245
 None
 1.02A 1lquA-5abjB:
undetectable		 1lquA-5abjB:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1357_1
(PROSTAGLANDIN
REDUCTASE 2)		 5abj VP3
VP4
(Enterovirus
A) 		4 / 6 TYR C 108
LEU C  44
ASN C  42
ASP D  45
 None
 1.12A 2w98A-5abjC:
undetectable
2w98B-5abjC:
undetectable		 2w98A-5abjC:
20.16
2w98B-5abjC:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9G_A_TOPA1159_1
(DIHYDROFOLATE
REDUCTASE)		 5abj VP3
(Enterovirus
A) 		5 / 10 LEU C  53
ALA C  88
LEU C 167
VAL C 117
ILE C 196
 None
 1.11A 2w9gA-5abjC:
undetectable		 2w9gA-5abjC:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9H_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE)		 5abj VP3
(Enterovirus
A) 		5 / 10 LEU C  53
ALA C  88
LEU C 167
VAL C 117
ILE C 196
 None
 1.05A 2w9hA-5abjC:
undetectable		 2w9hA-5abjC:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRB_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 5abj VP3
(Enterovirus
A) 		5 / 11 LEU C  53
ALA C  88
LEU C 167
VAL C 117
ILE C 196
 None
 1.10A 3frbX-5abjC:
undetectable		 3frbX-5abjC:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GVU_A_STIA1001_2
(TYROSINE-PROTEIN
KINASE ABL2)		 5abj VP2
(Enterovirus
A) 		4 / 5 VAL B 110
ILE B 238
TYR B 197
MET B 198
 None
 0.90A 3gvuA-5abjB:
undetectable		 3gvuA-5abjB:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 5abj VP2
(Enterovirus
A) 		4 / 4 PRO B  53
THR B  54
GLY B  93
THR B  87
 None
 1.03A 3ib1A-5abjB:
undetectable		 3ib1A-5abjB:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM201_1
(PROTEIN S100-A4)		 5abj VP2
(Enterovirus
A) 		4 / 7 GLY B 157
PHE B  82
GLY B 213
PHE B 212
 None
 0.95A 3ko0M-5abjB:
undetectable
3ko0P-5abjB:
undetectable		 3ko0M-5abjB:
18.68
3ko0P-5abjB:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5abj VP2
(Enterovirus
A) 		5 / 12 ARG B 103
GLY B  93
ALA B  96
PHE B 245
ALA B 243
 None
 1.03A 3sudA-5abjB:
undetectable		 3sudA-5abjB:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 5abj VP2
(Enterovirus
A) 		5 / 12 ARG B 103
GLY B  93
ALA B  96
PHE B 245
ALA B 243
 None
 0.97A 3sudC-5abjB:
undetectable		 3sudC-5abjB:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 5abj VP2
(Enterovirus
A) 		4 / 5 LEU B 215
TYR B 130
ALA B 168
ILE B 170
 None
 1.16A 4y03B-5abjB:
undetectable		 4y03B-5abjB:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)		 5abj VP2
(Enterovirus
A) 		4 / 4 VAL B 110
ALA B 191
ASN B 188
GLN B 181
 None
 1.46A 4zgfA-5abjB:
undetectable		 4zgfA-5abjB:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5abj VP2
(Enterovirus
A) 		3 / 3 SER B 205
ALA B 206
THR B  87
 None
 0.62A 5n0xB-5abjB:
undetectable		 5n0xB-5abjB:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 5abj VP3
(Enterovirus
A) 		4 / 5 ALA C 216
VAL C 117
PHE C  71
ILE C 194
 None
 1.01A 5of1A-5abjC:
4.3		 5of1A-5abjC:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 5abj VP3
(Enterovirus
A) 		4 / 5 ALA C 208
SER C 124
GLY C 123
TYR C 202
 None
 1.24A 5yodD-5abjC:
undetectable		 5yodD-5abjC:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 5abj VP2
VP3
(Enterovirus
A) 		5 / 12 VAL B  60
PRO C  37
VAL B 126
PHE B  92
PRO B  83
 None
 1.29A 6becA-5abjB:
undetectable
6becB-5abjB:
undetectable
6becC-5abjB:
3.4		 6becA-5abjB:
17.66
6becB-5abjB:
17.66
6becC-5abjB:
17.66