SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ac9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 5ac9 VP1
(Foot-and-mouth
disease
virus) 		3 / 3 THR 1  68
THR 1  70
PRO 1 188
 None
 0.84A 1a7yB-5ac91:
undetectable		 1a7yB-5ac91:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 5ac9 VP1
(Foot-and-mouth
disease
virus) 		3 / 3 THR 1  68
THR 1  70
PRO 1 188
 None
 0.83A 1fjaC-5ac91:
undetectable		 1fjaC-5ac91:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 5ac9 VP1
(Foot-and-mouth
disease
virus) 		3 / 3 THR 1  68
THR 1  70
PRO 1 188
 None
 0.83A 1fjaD-5ac91:
undetectable		 1fjaD-5ac91:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 5ac9 VP1
(Foot-and-mouth
disease
virus) 		3 / 3 THR 1  70
PRO 1 188
THR 1  68
 None
 0.87A 1i3wE-5ac91:
undetectable		 1i3wE-5ac91:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 5ac9 VP1
(Foot-and-mouth
disease
virus) 		4 / 7 VAL 1  78
LEU 1 115
THR 1 113
LEU 1 112
 None
 0.82A 1jgsA-5ac91:
undetectable		 1jgsA-5ac91:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 5ac9 VP1
(Foot-and-mouth
disease
virus) 		3 / 3 THR 1  68
THR 1  70
PRO 1 188
 None
 0.76A 1qfiB-5ac91:
undetectable		 1qfiB-5ac91:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 5ac9 VP1
(Foot-and-mouth
disease
virus) 		3 / 3 THR 1  68
THR 1  70
PRO 1 188
 None
 0.82A 1unjW-5ac91:
undetectable		 1unjW-5ac91:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 5ac9 VP1
(Foot-and-mouth
disease
virus) 		3 / 3 THR 1  70
PRO 1 188
THR 1  68
 None
 0.85A 1unmE-5ac91:
undetectable		 1unmE-5ac91:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 5ac9 VP1
(Foot-and-mouth
disease
virus) 		3 / 3 THR 1  68
THR 1  70
PRO 1 188
 None
 0.81A 1unmE-5ac91:
undetectable		 1unmE-5ac91:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 5ac9 VP1
(Foot-and-mouth
disease
virus) 		3 / 3 THR 1  70
PRO 1 188
THR 1  68
 None
 0.69A 209dC-5ac91:
undetectable		 209dC-5ac91:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 5ac9 VP1
(Foot-and-mouth
disease
virus) 		3 / 3 THR 1  68
THR 1  70
PRO 1 188
 None
 0.78A 209dC-5ac91:
undetectable		 209dC-5ac91:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 5ac9 VP1
(Foot-and-mouth
disease
virus) 		4 / 6 TRP 1  88
ILE 1 168
LEU 1  86
LEU 1  51
 None
 1.05A 2rlfA-5ac91:
undetectable
2rlfD-5ac91:
undetectable		 2rlfA-5ac91:
11.27
2rlfD-5ac91:
11.27