SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ado'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_2
(TRANSTHYRETIN)		 5ado FAB A.17
(Homo
sapiens) 		4 / 7 LEU L 137
THR L 174
SER L 164
THR L 166
 None
 0.77A 1ictD-5adoL:
undetectable		 1ictD-5adoL:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 5ado FAB A.17
(Homo
sapiens) 		4 / 5 LEU L 181
GLY L 130
PRO L 122
VAL L 134
 None
 0.91A 2aojA-5adoL:
undetectable		 2aojA-5adoL:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)		 5ado FAB A.17
(Homo
sapiens) 		5 / 12 ASP L  86
LYS L 105
PRO L   7
GLY L 101
LEU L   4
 None
 1.32A 2nv4B-5adoL:
undetectable		 2nv4B-5adoL:
20.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ACL_A_SASA1111_1
(MCG)		 5ado FAB A.17
(Homo
sapiens) 		4 / 7 TYR L  33
TYR L  37
TYR L  50
PRO L  56
 None
DEP  L1356 (-4.0A)
None
None
 0.56A 5aclA-5adoL:
21.1		 5aclA-5adoL:
35.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)		 5ado FAB A.17
(Homo
sapiens) 		4 / 7 ASP L 172
THR L 174
TYR L 142
THR L 111
 None
 1.37A 5b6iA-5adoL:
undetectable		 5b6iA-5adoL:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_B_ADNB302_1
(FLUORINASE)		 5ado FAB A.17
(Homo
sapiens) 		4 / 6 ASP L 172
THR L 174
TYR L 142
THR L 111
 None
 1.35A 5b6iB-5adoL:
undetectable		 5b6iB-5adoL:
23.80