SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5aeo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 5aeo R. EQUI VAPG PROTEIN
(Rhodococcus
hoagii) 		4 / 8 PHE A 103
ILE A 114
GLY A 125
PHE A 116
 None
 0.82A 1rtsA-5aeoA:
undetectable		 1rtsA-5aeoA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5aeo R. EQUI VAPG PROTEIN
(Rhodococcus
hoagii) 		4 / 7 ILE A 132
LEU A 112
THR A  61
LEU A  60
 None
 0.77A 2dyrN-5aeoA:
undetectable
2dyrW-5aeoA:
undetectable		 2dyrN-5aeoA:
15.81
2dyrW-5aeoA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5aeo R. EQUI VAPG PROTEIN
(Rhodococcus
hoagii) 		4 / 8 ILE A 132
LEU A 112
THR A  61
LEU A  60
 None
 0.74A 2eijN-5aeoA:
undetectable
2eijW-5aeoA:
undetectable		 2eijN-5aeoA:
15.81
2eijW-5aeoA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5aeo R. EQUI VAPG PROTEIN
(Rhodococcus
hoagii) 		4 / 8 ILE A 132
LEU A 112
THR A  61
LEU A  60
 None
 0.78A 2eikN-5aeoA:
undetectable
2eikW-5aeoA:
undetectable		 2eikN-5aeoA:
15.81
2eikW-5aeoA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5aeo R. EQUI VAPG PROTEIN
(Rhodococcus
hoagii) 		4 / 8 ILE A 132
LEU A 112
THR A  61
LEU A  60
 None
 0.74A 2eilN-5aeoA:
undetectable
2eilW-5aeoA:
undetectable		 2eilN-5aeoA:
15.81
2eilW-5aeoA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5aeo R. EQUI VAPG PROTEIN
(Rhodococcus
hoagii) 		4 / 8 ILE A 132
LEU A 112
THR A  61
LEU A  60
 None
 0.70A 3ag3N-5aeoA:
undetectable
3ag3W-5aeoA:
undetectable		 3ag3N-5aeoA:
15.81
3ag3W-5aeoA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5aeo R. EQUI VAPG PROTEIN
(Rhodococcus
hoagii) 		4 / 8 ILE A 132
LEU A 112
THR A  61
LEU A  60
 None
 0.75A 3asnN-5aeoA:
undetectable
3asnW-5aeoA:
undetectable		 3asnN-5aeoA:
15.81
3asnW-5aeoA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G9E_A_RO7A1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5aeo R. EQUI VAPG PROTEIN
(Rhodococcus
hoagii) 		5 / 12 GLY A 144
SER A  98
HIS A  95
LEU A  93
VAL A  62
 None
 1.13A 3g9eA-5aeoA:
undetectable		 3g9eA-5aeoA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 5aeo R. EQUI VAPG PROTEIN
(Rhodococcus
hoagii) 		4 / 7 PHE A 103
ILE A 114
GLY A 125
PHE A 116
 None
 0.87A 5h3aA-5aeoA:
undetectable		 5h3aA-5aeoA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 5aeo R. EQUI VAPG PROTEIN
(Rhodococcus
hoagii) 		3 / 3 VAL A 135
ALA A 107
GLN A  56
 None
 0.70A 6gb9A-5aeoA:
undetectable		 6gb9A-5aeoA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5aeo R. EQUI VAPG PROTEIN
(Rhodococcus
hoagii) 		4 / 7 ILE A 132
LEU A 112
THR A  61
LEU A  60
 None
 0.82A 6nmfA-5aeoA:
undetectable
6nmfJ-5aeoA:
undetectable		 6nmfA-5aeoA:
15.81
6nmfJ-5aeoA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5aeo R. EQUI VAPG PROTEIN
(Rhodococcus
hoagii) 		4 / 7 ILE A 132
LEU A 112
THR A  61
LEU A  60
 None
 0.83A 6nmpA-5aeoA:
undetectable
6nmpJ-5aeoA:
undetectable		 6nmpA-5aeoA:
15.81
6nmpJ-5aeoA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5aeo R. EQUI VAPG PROTEIN
(Rhodococcus
hoagii) 		4 / 5 ILE A 132
LEU A 112
THR A  61
LEU A  60
 None
 0.88A 6nmpN-5aeoA:
undetectable
6nmpW-5aeoA:
undetectable		 6nmpN-5aeoA:
15.81
6nmpW-5aeoA:
15.76