SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5aeu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3002_1
(SERUM ALBUMIN)		 5aeu BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Paraburkholderia
xenovorans) 		4 / 8 GLN B  24
LEU B  23
LEU B 156
SER B 132
 None
 1.10A 1hk2A-5aeuB:
undetectable		 1hk2A-5aeuB:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5aeu BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Paraburkholderia
xenovorans) 		4 / 7 ILE B 167
LEU B  50
ARG B  33
LEU B  38
 None
 0.91A 1v54N-5aeuB:
undetectable
1v54W-5aeuB:
undetectable		 1v54N-5aeuB:
15.05
1v54W-5aeuB:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5aeu BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Paraburkholderia
xenovorans) 		4 / 8 ILE B 167
LEU B  50
ARG B  33
LEU B  38
 None
 0.83A 2eijN-5aeuB:
undetectable
2eijW-5aeuB:
undetectable		 2eijN-5aeuB:
15.05
2eijW-5aeuB:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 5aeu BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Paraburkholderia
xenovorans) 		3 / 3 TYR B  56
ASP B 154
HIS B 112
 None
 0.71A 3e23A-5aeuB:
undetectable		 3e23A-5aeuB:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_B_032B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5aeu BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Paraburkholderia
xenovorans) 		4 / 5 ILE B 135
PHE B 187
SER B 115
ASP B  39
 None
 1.18A 4rzvB-5aeuB:
undetectable		 4rzvB-5aeuB:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA305_0
(THAUMATIN-1)		 5aeu BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Paraburkholderia
xenovorans) 		4 / 5 GLU B  26
ILE B  27
PHE B 128
VAL B 119
 None
 1.44A 4tvtA-5aeuB:
undetectable		 4tvtA-5aeuB:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5aeu BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Paraburkholderia
xenovorans) 		4 / 6 PHE B 165
GLU B  28
ARG B 158
VAL B 130
 None
 1.26A 5ad8A-5aeuB:
undetectable
5ad8B-5aeuB:
undetectable		 5ad8A-5aeuB:
15.61
5ad8B-5aeuB:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5aeu BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Paraburkholderia
xenovorans) 		4 / 7 ILE B 167
LEU B  50
ARG B  33
LEU B  38
 None
 0.85A 5b1bA-5aeuB:
undetectable
5b1bJ-5aeuB:
undetectable		 5b1bA-5aeuB:
15.05
5b1bJ-5aeuB:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5aeu BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Paraburkholderia
xenovorans) 		4 / 7 ILE B 167
LEU B  50
ARG B  33
LEU B  38
 None
 0.87A 5iy5A-5aeuB:
undetectable
5iy5J-5aeuB:
undetectable		 5iy5A-5aeuB:
15.05
5iy5J-5aeuB:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5aeu BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Paraburkholderia
xenovorans) 		4 / 7 PHE B 165
GLU B  28
ARG B 158
VAL B 130
 None
 1.24A 5unuA-5aeuB:
undetectable
5unuB-5aeuB:
undetectable		 5unuA-5aeuB:
15.61
5unuB-5aeuB:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5aeu BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Paraburkholderia
xenovorans) 		4 / 7 PHE B 165
GLU B  28
ARG B 158
VAL B 130
 None
 1.25A 5unwA-5aeuB:
undetectable
5unwB-5aeuB:
undetectable		 5unwA-5aeuB:
15.61
5unwB-5aeuB:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5aeu BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Paraburkholderia
xenovorans) 		4 / 7 ARG B 158
VAL B 130
PHE B 165
GLU B  28
 None
 1.30A 5unxA-5aeuB:
undetectable
5unxB-5aeuB:
undetectable		 5unxA-5aeuB:
15.61
5unxB-5aeuB:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5aeu BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Paraburkholderia
xenovorans) 		4 / 6 PHE B 165
GLU B  28
ARG B 158
VAL B 130
 None
 1.26A 5unxA-5aeuB:
undetectable
5unxB-5aeuB:
undetectable		 5unxA-5aeuB:
15.61
5unxB-5aeuB:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5aeu BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Paraburkholderia
xenovorans) 		4 / 7 PHE B 165
GLU B  28
ARG B 158
VAL B 130
 None
 1.26A 5uo6A-5aeuB:
undetectable
5uo6B-5aeuB:
undetectable		 5uo6A-5aeuB:
18.09
5uo6B-5aeuB:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5aeu BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Paraburkholderia
xenovorans) 		4 / 7 ILE B 167
LEU B  50
ARG B  33
LEU B  38
 None
 0.91A 5xdqA-5aeuB:
undetectable
5xdqJ-5aeuB:
undetectable		 5xdqA-5aeuB:
15.05
5xdqJ-5aeuB:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5aeu BIPHENYL DIOXYGENASE
SUBUNIT BETA
(Paraburkholderia
xenovorans) 		4 / 8 ILE B 167
LEU B  50
ARG B  33
LEU B  38
 None
 0.93A 5zcqN-5aeuB:
undetectable
5zcqW-5aeuB:
undetectable		 5zcqN-5aeuB:
15.05
5zcqW-5aeuB:
18.71