SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ah1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A  85
PHE A  86
SER A 182
MET A 183
HIS A 426
 None
 0.52A 1a8uA-5ah1A:
13.5		 1a8uA-5ah1A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A  85
PHE A  86
SER A 182
MET A 183
HIS A 426
 None
 0.49A 1a8uB-5ah1A:
13.4		 1a8uB-5ah1A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.28A 1c9sA-5ah1A:
undetectable
1c9sK-5ah1A:
undetectable		 1c9sA-5ah1A:
10.95
1c9sK-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.32A 1c9sB-5ah1A:
undetectable
1c9sC-5ah1A:
undetectable		 1c9sB-5ah1A:
10.95
1c9sC-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.29A 1c9sC-5ah1A:
undetectable
1c9sD-5ah1A:
undetectable		 1c9sC-5ah1A:
10.95
1c9sD-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.30A 1c9sD-5ah1A:
undetectable
1c9sE-5ah1A:
undetectable		 1c9sD-5ah1A:
10.95
1c9sE-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.29A 1c9sE-5ah1A:
undetectable
1c9sF-5ah1A:
undetectable		 1c9sE-5ah1A:
10.95
1c9sF-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.26A 1c9sF-5ah1A:
undetectable
1c9sG-5ah1A:
undetectable		 1c9sF-5ah1A:
10.95
1c9sG-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.30A 1c9sG-5ah1A:
undetectable
1c9sH-5ah1A:
undetectable		 1c9sG-5ah1A:
10.95
1c9sH-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.31A 1c9sH-5ah1A:
undetectable
1c9sI-5ah1A:
undetectable		 1c9sH-5ah1A:
10.95
1c9sI-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.32A 1c9sJ-5ah1A:
undetectable
1c9sK-5ah1A:
undetectable		 1c9sJ-5ah1A:
10.95
1c9sK-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.28A 1gtfA-5ah1A:
undetectable
1gtfK-5ah1A:
undetectable		 1gtfA-5ah1A:
10.95
1gtfK-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.30A 1gtfB-5ah1A:
undetectable
1gtfC-5ah1A:
undetectable		 1gtfB-5ah1A:
10.95
1gtfC-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.29A 1gtfC-5ah1A:
undetectable
1gtfD-5ah1A:
undetectable		 1gtfC-5ah1A:
10.95
1gtfD-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.28A 1gtfE-5ah1A:
undetectable
1gtfF-5ah1A:
undetectable		 1gtfE-5ah1A:
10.95
1gtfF-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.30A 1gtfG-5ah1A:
undetectable
1gtfH-5ah1A:
undetectable		 1gtfG-5ah1A:
10.95
1gtfH-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.31A 1gtfH-5ah1A:
undetectable
1gtfI-5ah1A:
undetectable		 1gtfH-5ah1A:
10.95
1gtfI-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.32A 1gtfI-5ah1A:
undetectable
1gtfJ-5ah1A:
undetectable		 1gtfI-5ah1A:
10.95
1gtfJ-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.33A 1gtfM-5ah1A:
undetectable
1gtfN-5ah1A:
undetectable		 1gtfM-5ah1A:
10.95
1gtfN-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.33A 1gtfP-5ah1A:
undetectable
1gtfQ-5ah1A:
undetectable		 1gtfP-5ah1A:
10.95
1gtfQ-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.35A 1gtfT-5ah1A:
undetectable
1gtfU-5ah1A:
undetectable		 1gtfT-5ah1A:
10.95
1gtfU-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.32A 1gtnG-5ah1A:
undetectable
1gtnH-5ah1A:
undetectable		 1gtnG-5ah1A:
10.95
1gtnH-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.30A 1gtnN-5ah1A:
undetectable
1gtnO-5ah1A:
undetectable		 1gtnN-5ah1A:
10.95
1gtnO-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.33A 1gtnQ-5ah1A:
undetectable
1gtnR-5ah1A:
undetectable		 1gtnQ-5ah1A:
10.95
1gtnR-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.30A 1gtnS-5ah1A:
undetectable
1gtnT-5ah1A:
undetectable		 1gtnS-5ah1A:
10.95
1gtnT-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		4 / 8 PHE A 250
LEU A 271
VAL A 125
THR A 305
 None
 1.13A 1o76B-5ah1A:
undetectable		 1o76B-5ah1A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_D_DEXD4999_2
(GLUCOCORTICOID
RECEPTOR)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		4 / 5 LEU A 253
TRP A 297
LEU A  33
GLN A 284
 None
 1.41A 1p93D-5ah1A:
undetectable		 1p93D-5ah1A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_A_IPHA6012_0
(PHENOL
2-MONOOXYGENASE)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 101
VAL A 104
MET A  55
ILE A  52
GLY A 431
 None
 1.46A 1pn0A-5ah1A:
undetectable		 1pn0A-5ah1A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_B_IPHB6022_0
(PHENOL
2-MONOOXYGENASE)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 101
VAL A 104
MET A  55
ILE A  52
GLY A 431
 None
 1.48A 1pn0B-5ah1A:
undetectable		 1pn0B-5ah1A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		4 / 7 PHE A 329
TYR A 443
LEU A 447
THR A 226
 None
 1.09A 1rmtB-5ah1A:
undetectable		 1rmtB-5ah1A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		4 / 8 PHE A 329
TYR A 443
LEU A 447
THR A 226
 None
 1.06A 1rmtD-5ah1A:
undetectable		 1rmtD-5ah1A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.33A 1utdA-5ah1A:
undetectable
1utdB-5ah1A:
undetectable		 1utdA-5ah1A:
10.95
1utdB-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.31A 1utdC-5ah1A:
undetectable
1utdD-5ah1A:
undetectable		 1utdC-5ah1A:
10.95
1utdD-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.30A 1utdD-5ah1A:
undetectable
1utdE-5ah1A:
undetectable		 1utdD-5ah1A:
10.95
1utdE-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.34A 1utdG-5ah1A:
undetectable
1utdH-5ah1A:
undetectable		 1utdG-5ah1A:
10.95
1utdH-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.31A 1utdA-5ah1A:
undetectable
1utdK-5ah1A:
undetectable		 1utdA-5ah1A:
10.95
1utdK-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.38A 1utdN-5ah1A:
undetectable
1utdO-5ah1A:
undetectable		 1utdN-5ah1A:
10.95
1utdO-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.29A 1utdQ-5ah1A:
undetectable
1utdR-5ah1A:
undetectable		 1utdQ-5ah1A:
10.95
1utdR-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.36A 1utdR-5ah1A:
undetectable
1utdS-5ah1A:
undetectable		 1utdR-5ah1A:
10.95
1utdS-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		4 / 7 SER A 228
ILE A 227
THR A 119
GLY A  88
 None
 0.96A 2v0mB-5ah1A:
undetectable		 2v0mB-5ah1A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YDO_A_ADNA400_1
(ADENOSINE RECEPTOR
A2A)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 12 PHE A 446
MET A 418
ASN A 416
SER A 223
HIS A 177
 None
 1.45A 2ydoA-5ah1A:
undetectable		 2ydoA-5ah1A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		4 / 8 ILE A  30
PRO A  31
VAL A 386
GLY A 385
 None
 0.78A 3em0B-5ah1A:
undetectable		 3em0B-5ah1A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		4 / 6 LEU A 239
SER A 237
ILE A  30
PHE A 250
 None
K  A1457 (-4.9A)
None
None
 1.02A 3ko0S-5ah1A:
undetectable		 3ko0S-5ah1A:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_0
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 12 PHE A 329
SER A 225
THR A 226
ILE A 412
LEU A 178
 None
 1.26A 3lcvB-5ah1A:
undetectable		 3lcvB-5ah1A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		3 / 3 HIS A 426
HIS A 181
MET A 427
 None
 1.01A 3mihA-5ah1A:
undetectable		 3mihA-5ah1A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 12 LEU A 269
VAL A 125
LEU A 292
ALA A 242
LEU A 245
 None
 1.17A 3ozuA-5ah1A:
undetectable		 3ozuA-5ah1A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ4_X_DXCX75_0
(CYTOCHROME C7)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 ILE A 288
LEU A 269
ILE A 266
PHE A  89
GLY A  88
 None
 1.14A 3sj4X-5ah1A:
undetectable		 3sj4X-5ah1A:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4APJ_A_ACTA1635_0
(ANGIOTENSIN-CONVERTI
NG ENZYME
BRADYKININ-POTENTIAT
ING PEPTIDE B)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		4 / 6 GLU A 311
ASP A 238
SER A 309
PRO A 374
 None
 1.39A 4apjA-5ah1A:
undetectable
4apjP-5ah1A:
undetectable		 4apjA-5ah1A:
21.24
4apjP-5ah1A:
4.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 12 HIS A  84
PHE A  89
ILE A 246
ILE A 303
PHE A  86
 None
 1.32A 4drhA-5ah1A:
undetectable		 4drhA-5ah1A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
ASP A  92
ASP A 272
ASP A 268
GLU A  93
 None
 1.44A 4feuC-5ah1A:
0.0		 4feuC-5ah1A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
ASP A  92
ASP A 272
ASP A 268
GLU A  93
 None
 1.43A 4fevA-5ah1A:
0.0		 4fevA-5ah1A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
ASP A  92
ASP A 272
ASP A 268
GLU A  93
 None
 1.39A 4fexA-5ah1A:
0.0
4fexB-5ah1A:
0.0		 4fexA-5ah1A:
18.70
4fexB-5ah1A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		3 / 3 GLN A 186
THR A 187
THR A 190
 None
 0.83A 4fu9A-5ah1A:
undetectable		 4fu9A-5ah1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		3 / 3 GLN A 186
THR A 187
THR A 190
 None
 0.81A 4fufA-5ah1A:
undetectable		 4fufA-5ah1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		4 / 6 ASP A  92
ASP A 272
ASP A 268
GLU A  93
 None
 1.29A 4gkhJ-5ah1A:
undetectable		 4gkhJ-5ah1A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		4 / 7 ILE A 227
THR A 333
VAL A 224
ASP A 401
 None
 1.21A 4iarA-5ah1A:
undetectable		 4iarA-5ah1A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_F_CAMF502_0
(CAMPHOR
5-MONOOXYGENASE)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		4 / 4 TYR A 267
THR A 249
VAL A 125
ILE A 288
 None
 1.23A 4jx1F-5ah1A:
undetectable		 4jx1F-5ah1A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 11 SER A 399
GLY A 398
ALA A 313
LEU A 316
ALA A 120
 None
 0.97A 4l6v1-5ah1A:
undetectable
4l6v6-5ah1A:
undetectable		 4l6v1-5ah1A:
19.45
4l6v6-5ah1A:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		4 / 7 TYR A 138
GLN A 284
LEU A 253
THR A 257
 None
 1.05A 4mbsA-5ah1A:
undetectable		 4mbsA-5ah1A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_2
(HISTONE DEACETYLASE
8)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		3 / 3 PRO A 419
MET A 418
TYR A 406
 None
 1.09A 4qa0B-5ah1A:
undetectable		 4qa0B-5ah1A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_0
(PROLINE--TRNA LIGASE)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 12 GLU A  66
VAL A  67
HIS A 177
PHE A 329
SER A 223
 None
 1.49A 4ydqB-5ah1A:
undetectable		 4ydqB-5ah1A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		4 / 5 ALA A 417
TYR A 406
HIS A 115
PHE A 446
 None
 1.15A 4ze2A-5ah1A:
undetectable		 4ze2A-5ah1A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.33A 5eeuB-5ah1A:
undetectable
5eeuC-5ah1A:
undetectable		 5eeuB-5ah1A:
10.95
5eeuC-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.27A 5eeuD-5ah1A:
undetectable
5eeuE-5ah1A:
undetectable		 5eeuD-5ah1A:
10.95
5eeuE-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5eeuE-5ah1A:
undetectable
5eeuF-5ah1A:
undetectable		 5eeuE-5ah1A:
10.95
5eeuF-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.33A 5eeuG-5ah1A:
undetectable
5eeuH-5ah1A:
undetectable		 5eeuG-5ah1A:
10.95
5eeuH-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.32A 5eeuH-5ah1A:
undetectable
5eeuI-5ah1A:
undetectable		 5eeuH-5ah1A:
10.95
5eeuI-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5eeuJ-5ah1A:
undetectable
5eeuK-5ah1A:
undetectable		 5eeuJ-5ah1A:
10.95
5eeuK-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.32A 5eeuA-5ah1A:
undetectable
5eeuK-5ah1A:
undetectable		 5eeuA-5ah1A:
10.95
5eeuK-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.35A 5eeuL-5ah1A:
undetectable
5eeuM-5ah1A:
undetectable		 5eeuL-5ah1A:
10.95
5eeuM-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.34A 5eeuM-5ah1A:
undetectable
5eeuN-5ah1A:
undetectable		 5eeuM-5ah1A:
10.95
5eeuN-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.32A 5eeuN-5ah1A:
undetectable
5eeuO-5ah1A:
undetectable		 5eeuN-5ah1A:
10.95
5eeuO-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.35A 5eeuU-5ah1A:
undetectable
5eeuV-5ah1A:
undetectable		 5eeuU-5ah1A:
10.95
5eeuV-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5eevB-5ah1A:
undetectable
5eevC-5ah1A:
undetectable		 5eevB-5ah1A:
10.95
5eevC-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.27A 5eevD-5ah1A:
undetectable
5eevE-5ah1A:
undetectable		 5eevD-5ah1A:
10.95
5eevE-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5eevE-5ah1A:
undetectable
5eevF-5ah1A:
undetectable		 5eevE-5ah1A:
10.95
5eevF-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.32A 5eevG-5ah1A:
undetectable
5eevH-5ah1A:
undetectable		 5eevG-5ah1A:
10.95
5eevH-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.32A 5eevH-5ah1A:
undetectable
5eevI-5ah1A:
undetectable		 5eevH-5ah1A:
10.95
5eevI-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5eevJ-5ah1A:
undetectable
5eevK-5ah1A:
undetectable		 5eevJ-5ah1A:
10.95
5eevK-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.32A 5eevA-5ah1A:
undetectable
5eevK-5ah1A:
undetectable		 5eevA-5ah1A:
10.95
5eevK-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.34A 5eevL-5ah1A:
undetectable
5eevM-5ah1A:
undetectable		 5eevL-5ah1A:
10.95
5eevM-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.33A 5eevM-5ah1A:
undetectable
5eevN-5ah1A:
undetectable		 5eevM-5ah1A:
10.95
5eevN-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.33A 5eevN-5ah1A:
undetectable
5eevO-5ah1A:
undetectable		 5eevN-5ah1A:
10.95
5eevO-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.35A 5eevU-5ah1A:
undetectable
5eevV-5ah1A:
undetectable		 5eevU-5ah1A:
10.95
5eevV-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5eewB-5ah1A:
undetectable
5eewC-5ah1A:
undetectable		 5eewB-5ah1A:
10.95
5eewC-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.27A 5eewD-5ah1A:
undetectable
5eewE-5ah1A:
undetectable		 5eewD-5ah1A:
10.95
5eewE-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5eewE-5ah1A:
undetectable
5eewF-5ah1A:
undetectable		 5eewE-5ah1A:
10.95
5eewF-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.32A 5eewG-5ah1A:
undetectable
5eewH-5ah1A:
undetectable		 5eewG-5ah1A:
10.95
5eewH-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.32A 5eewH-5ah1A:
undetectable
5eewI-5ah1A:
undetectable		 5eewH-5ah1A:
10.95
5eewI-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5eewJ-5ah1A:
undetectable
5eewK-5ah1A:
undetectable		 5eewJ-5ah1A:
10.95
5eewK-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.32A 5eewA-5ah1A:
undetectable
5eewK-5ah1A:
undetectable		 5eewA-5ah1A:
10.95
5eewK-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.34A 5eewL-5ah1A:
undetectable
5eewM-5ah1A:
undetectable		 5eewL-5ah1A:
10.95
5eewM-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.33A 5eewM-5ah1A:
undetectable
5eewN-5ah1A:
undetectable		 5eewM-5ah1A:
10.95
5eewN-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.33A 5eewN-5ah1A:
undetectable
5eewO-5ah1A:
undetectable		 5eewN-5ah1A:
10.95
5eewO-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.35A 5eewU-5ah1A:
undetectable
5eewV-5ah1A:
undetectable		 5eewU-5ah1A:
10.95
5eewV-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5eexB-5ah1A:
undetectable
5eexC-5ah1A:
undetectable		 5eexB-5ah1A:
10.95
5eexC-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.27A 5eexD-5ah1A:
undetectable
5eexE-5ah1A:
undetectable		 5eexD-5ah1A:
10.95
5eexE-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5eexE-5ah1A:
undetectable
5eexF-5ah1A:
undetectable		 5eexE-5ah1A:
10.95
5eexF-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.32A 5eexG-5ah1A:
undetectable
5eexH-5ah1A:
undetectable		 5eexG-5ah1A:
10.95
5eexH-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.32A 5eexH-5ah1A:
undetectable
5eexI-5ah1A:
undetectable		 5eexH-5ah1A:
10.95
5eexI-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 11 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.30A 5eexI-5ah1A:
undetectable
5eexJ-5ah1A:
undetectable		 5eexI-5ah1A:
10.95
5eexJ-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.35A 5eexJ-5ah1A:
undetectable
5eexK-5ah1A:
undetectable		 5eexJ-5ah1A:
10.95
5eexK-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.32A 5eexA-5ah1A:
undetectable
5eexK-5ah1A:
undetectable		 5eexA-5ah1A:
10.95
5eexK-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.34A 5eexL-5ah1A:
undetectable
5eexM-5ah1A:
undetectable		 5eexL-5ah1A:
10.95
5eexM-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.33A 5eexM-5ah1A:
undetectable
5eexN-5ah1A:
undetectable		 5eexM-5ah1A:
10.95
5eexN-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.32A 5eexN-5ah1A:
undetectable
5eexO-5ah1A:
undetectable		 5eexN-5ah1A:
10.95
5eexO-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.35A 5eexQ-5ah1A:
undetectable
5eexR-5ah1A:
undetectable		 5eexQ-5ah1A:
10.95
5eexR-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.35A 5eexU-5ah1A:
undetectable
5eexV-5ah1A:
undetectable		 5eexU-5ah1A:
10.95
5eexV-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5eeyB-5ah1A:
undetectable
5eeyC-5ah1A:
undetectable		 5eeyB-5ah1A:
10.95
5eeyC-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.27A 5eeyD-5ah1A:
undetectable
5eeyE-5ah1A:
undetectable		 5eeyD-5ah1A:
10.95
5eeyE-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5eeyE-5ah1A:
undetectable
5eeyF-5ah1A:
undetectable		 5eeyE-5ah1A:
10.95
5eeyF-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.32A 5eeyG-5ah1A:
undetectable
5eeyH-5ah1A:
undetectable		 5eeyG-5ah1A:
10.95
5eeyH-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.32A 5eeyH-5ah1A:
undetectable
5eeyI-5ah1A:
undetectable		 5eeyH-5ah1A:
10.95
5eeyI-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 11 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.30A 5eeyI-5ah1A:
undetectable
5eeyJ-5ah1A:
undetectable		 5eeyI-5ah1A:
10.95
5eeyJ-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5eeyJ-5ah1A:
undetectable
5eeyK-5ah1A:
undetectable		 5eeyJ-5ah1A:
10.95
5eeyK-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.32A 5eeyA-5ah1A:
undetectable
5eeyK-5ah1A:
undetectable		 5eeyA-5ah1A:
10.95
5eeyK-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.34A 5eeyL-5ah1A:
undetectable
5eeyM-5ah1A:
undetectable		 5eeyL-5ah1A:
10.95
5eeyM-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.33A 5eeyM-5ah1A:
undetectable
5eeyN-5ah1A:
undetectable		 5eeyM-5ah1A:
10.95
5eeyN-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.32A 5eeyN-5ah1A:
undetectable
5eeyO-5ah1A:
undetectable		 5eeyN-5ah1A:
10.95
5eeyO-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.35A 5eeyQ-5ah1A:
undetectable
5eeyR-5ah1A:
undetectable		 5eeyQ-5ah1A:
10.95
5eeyR-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.35A 5eeyU-5ah1A:
undetectable
5eeyV-5ah1A:
undetectable		 5eeyU-5ah1A:
10.95
5eeyV-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5eezB-5ah1A:
undetectable
5eezC-5ah1A:
undetectable		 5eezB-5ah1A:
10.95
5eezC-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.27A 5eezD-5ah1A:
undetectable
5eezE-5ah1A:
undetectable		 5eezD-5ah1A:
10.95
5eezE-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.32A 5eezG-5ah1A:
undetectable
5eezH-5ah1A:
undetectable		 5eezG-5ah1A:
10.95
5eezH-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.32A 5eezH-5ah1A:
undetectable
5eezI-5ah1A:
undetectable		 5eezH-5ah1A:
10.95
5eezI-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 11 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.30A 5eezI-5ah1A:
undetectable
5eezJ-5ah1A:
undetectable		 5eezI-5ah1A:
10.95
5eezJ-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5eezJ-5ah1A:
undetectable
5eezK-5ah1A:
undetectable		 5eezJ-5ah1A:
10.95
5eezK-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.32A 5eezA-5ah1A:
undetectable
5eezK-5ah1A:
undetectable		 5eezA-5ah1A:
10.95
5eezK-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.34A 5eezL-5ah1A:
undetectable
5eezM-5ah1A:
undetectable		 5eezL-5ah1A:
10.95
5eezM-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.33A 5eezM-5ah1A:
undetectable
5eezN-5ah1A:
undetectable		 5eezM-5ah1A:
10.95
5eezN-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.32A 5eezN-5ah1A:
undetectable
5eezO-5ah1A:
undetectable		 5eezN-5ah1A:
10.95
5eezO-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.35A 5eezQ-5ah1A:
undetectable
5eezR-5ah1A:
undetectable		 5eezQ-5ah1A:
10.95
5eezR-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.35A 5eezU-5ah1A:
undetectable
5eezV-5ah1A:
undetectable		 5eezU-5ah1A:
10.95
5eezV-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5ef0B-5ah1A:
undetectable
5ef0C-5ah1A:
undetectable		 5ef0B-5ah1A:
10.95
5ef0C-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.27A 5ef0D-5ah1A:
undetectable
5ef0E-5ah1A:
undetectable		 5ef0D-5ah1A:
10.95
5ef0E-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.32A 5ef0G-5ah1A:
undetectable
5ef0H-5ah1A:
undetectable		 5ef0G-5ah1A:
10.95
5ef0H-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.32A 5ef0H-5ah1A:
undetectable
5ef0I-5ah1A:
undetectable		 5ef0H-5ah1A:
10.95
5ef0I-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 11 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.30A 5ef0I-5ah1A:
undetectable
5ef0J-5ah1A:
undetectable		 5ef0I-5ah1A:
10.95
5ef0J-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5ef0J-5ah1A:
undetectable
5ef0K-5ah1A:
undetectable		 5ef0J-5ah1A:
10.95
5ef0K-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.32A 5ef0A-5ah1A:
undetectable
5ef0K-5ah1A:
undetectable		 5ef0A-5ah1A:
10.95
5ef0K-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.34A 5ef0L-5ah1A:
undetectable
5ef0M-5ah1A:
undetectable		 5ef0L-5ah1A:
10.95
5ef0M-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.33A 5ef0M-5ah1A:
undetectable
5ef0N-5ah1A:
undetectable		 5ef0M-5ah1A:
10.95
5ef0N-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.32A 5ef0N-5ah1A:
undetectable
5ef0O-5ah1A:
undetectable		 5ef0N-5ah1A:
10.95
5ef0O-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.35A 5ef0Q-5ah1A:
undetectable
5ef0R-5ah1A:
undetectable		 5ef0Q-5ah1A:
10.95
5ef0R-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.35A 5ef0U-5ah1A:
undetectable
5ef0V-5ah1A:
undetectable		 5ef0U-5ah1A:
10.95
5ef0V-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5ef1B-5ah1A:
undetectable
5ef1C-5ah1A:
undetectable		 5ef1B-5ah1A:
10.95
5ef1C-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.27A 5ef1D-5ah1A:
undetectable
5ef1E-5ah1A:
undetectable		 5ef1D-5ah1A:
10.95
5ef1E-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.32A 5ef1G-5ah1A:
undetectable
5ef1H-5ah1A:
undetectable		 5ef1G-5ah1A:
10.95
5ef1H-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.31A 5ef1H-5ah1A:
undetectable
5ef1I-5ah1A:
undetectable		 5ef1H-5ah1A:
10.95
5ef1I-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 11 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.31A 5ef1I-5ah1A:
undetectable
5ef1J-5ah1A:
undetectable		 5ef1I-5ah1A:
10.95
5ef1J-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5ef1J-5ah1A:
undetectable
5ef1K-5ah1A:
undetectable		 5ef1J-5ah1A:
10.95
5ef1K-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.32A 5ef1A-5ah1A:
undetectable
5ef1K-5ah1A:
undetectable		 5ef1A-5ah1A:
10.95
5ef1K-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.34A 5ef1L-5ah1A:
undetectable
5ef1M-5ah1A:
undetectable		 5ef1L-5ah1A:
10.95
5ef1M-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.33A 5ef1M-5ah1A:
undetectable
5ef1N-5ah1A:
undetectable		 5ef1M-5ah1A:
10.95
5ef1N-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.32A 5ef1N-5ah1A:
undetectable
5ef1O-5ah1A:
undetectable		 5ef1N-5ah1A:
10.95
5ef1O-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.35A 5ef1Q-5ah1A:
undetectable
5ef1R-5ah1A:
undetectable		 5ef1Q-5ah1A:
10.95
5ef1R-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.35A 5ef1U-5ah1A:
undetectable
5ef1V-5ah1A:
undetectable		 5ef1U-5ah1A:
10.95
5ef1V-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5ef2B-5ah1A:
undetectable
5ef2C-5ah1A:
undetectable		 5ef2B-5ah1A:
10.95
5ef2C-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.27A 5ef2D-5ah1A:
undetectable
5ef2E-5ah1A:
undetectable		 5ef2D-5ah1A:
10.95
5ef2E-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.32A 5ef2G-5ah1A:
undetectable
5ef2H-5ah1A:
undetectable		 5ef2G-5ah1A:
10.95
5ef2H-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.31A 5ef2H-5ah1A:
undetectable
5ef2I-5ah1A:
undetectable		 5ef2H-5ah1A:
10.95
5ef2I-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 11 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.31A 5ef2I-5ah1A:
undetectable
5ef2J-5ah1A:
undetectable		 5ef2I-5ah1A:
10.95
5ef2J-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5ef2J-5ah1A:
undetectable
5ef2K-5ah1A:
undetectable		 5ef2J-5ah1A:
10.95
5ef2K-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.32A 5ef2A-5ah1A:
undetectable
5ef2K-5ah1A:
undetectable		 5ef2A-5ah1A:
10.95
5ef2K-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.34A 5ef2L-5ah1A:
undetectable
5ef2M-5ah1A:
undetectable		 5ef2L-5ah1A:
10.95
5ef2M-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.33A 5ef2M-5ah1A:
undetectable
5ef2N-5ah1A:
undetectable		 5ef2M-5ah1A:
10.95
5ef2N-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.32A 5ef2N-5ah1A:
undetectable
5ef2O-5ah1A:
undetectable		 5ef2N-5ah1A:
10.95
5ef2O-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.35A 5ef2Q-5ah1A:
undetectable
5ef2R-5ah1A:
undetectable		 5ef2Q-5ah1A:
10.95
5ef2R-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.35A 5ef2U-5ah1A:
undetectable
5ef2V-5ah1A:
undetectable		 5ef2U-5ah1A:
10.95
5ef2V-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5ef3B-5ah1A:
undetectable
5ef3C-5ah1A:
undetectable		 5ef3B-5ah1A:
10.95
5ef3C-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.27A 5ef3D-5ah1A:
undetectable
5ef3E-5ah1A:
undetectable		 5ef3D-5ah1A:
10.95
5ef3E-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.32A 5ef3G-5ah1A:
undetectable
5ef3H-5ah1A:
undetectable		 5ef3G-5ah1A:
10.95
5ef3H-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.32A 5ef3H-5ah1A:
undetectable
5ef3I-5ah1A:
undetectable		 5ef3H-5ah1A:
10.95
5ef3I-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 11 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.31A 5ef3I-5ah1A:
undetectable
5ef3J-5ah1A:
undetectable		 5ef3I-5ah1A:
10.95
5ef3J-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 SER A 126
GLY A 184
HIS A  84
ALA A 304
THR A 187
 None
 1.34A 5ef3J-5ah1A:
undetectable
5ef3K-5ah1A:
undetectable		 5ef3J-5ah1A:
10.95
5ef3K-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.33A 5ef3A-5ah1A:
undetectable
5ef3K-5ah1A:
undetectable		 5ef3A-5ah1A:
10.95
5ef3K-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_M_TRPM101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.34A 5ef3L-5ah1A:
undetectable
5ef3M-5ah1A:
undetectable		 5ef3L-5ah1A:
10.95
5ef3M-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_N_TRPN101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.33A 5ef3M-5ah1A:
undetectable
5ef3N-5ah1A:
undetectable		 5ef3M-5ah1A:
10.95
5ef3N-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.32A 5ef3N-5ah1A:
undetectable
5ef3O-5ah1A:
undetectable		 5ef3N-5ah1A:
10.95
5ef3O-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 9 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.35A 5ef3Q-5ah1A:
undetectable
5ef3R-5ah1A:
undetectable		 5ef3Q-5ah1A:
10.95
5ef3R-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 GLY A 184
HIS A  84
ALA A 304
THR A 187
SER A 126
 None
 1.35A 5ef3U-5ah1A:
undetectable
5ef3V-5ah1A:
undetectable		 5ef3U-5ah1A:
10.95
5ef3V-5ah1A:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A210_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 12 VAL A 386
PHE A 356
HIS A 426
VAL A 430
GLY A  88
 None
 1.42A 5i8fA-5ah1A:
undetectable		 5i8fA-5ah1A:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		4 / 7 HIS A 426
ILE A 429
VAL A 430
TYR A 440
 None
 1.15A 5kkzC-5ah1A:
undetectable
5kkzE-5ah1A:
undetectable		 5kkzC-5ah1A:
16.31
5kkzE-5ah1A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_K_ASCK1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		4 / 7 HIS A 426
ILE A 429
VAL A 430
TYR A 440
 None
 1.13A 5kkzK-5ah1A:
undetectable
5kkzQ-5ah1A:
undetectable		 5kkzK-5ah1A:
22.12
5kkzQ-5ah1A:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		3 / 3 HIS A 150
LYS A 153
PHE A 154
 ZN  A1455 (-3.3A)
None
None
 1.24A 5klaA-5ah1A:
undetectable		 5klaA-5ah1A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_D_SAMD501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 10 LEU A  82
HIS A  84
ILE A 179
GLY A 180
GLY A 184
 None
 0.99A 5o96C-5ah1A:
undetectable
5o96D-5ah1A:
undetectable		 5o96C-5ah1A:
20.13
5o96D-5ah1A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA814_0
(UNCHARACTERIZED
PROTEIN)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		4 / 5 TYR A 366
ASN A 388
THR A 234
LEU A 236
 None
 1.34A 6d8pA-5ah1A:
1.1		 6d8pA-5ah1A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DCH_A_ACTA401_0
(SCOE PROTEIN)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		4 / 5 THR A 300
HIS A 156
ASP A 130
HIS A 150
 None
ZN  A1455 (-3.3A)
ZN  A1455 (-2.0A)
ZN  A1455 (-3.3A)
 1.29A 6dchA-5ah1A:
undetectable		 6dchA-5ah1A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		4 / 6 TRP A 319
MET A 183
GLY A 233
LEU A 316
 None
 0.91A 6fosA-5ah1A:
undetectable		 6fosA-5ah1A:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		5 / 12 TYR A 146
TRP A 274
ARG A 161
GLU A  93
GLY A  90
 None
 1.32A 6gngA-5ah1A:
4.9		 6gngA-5ah1A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MVX_A_K4DA1304_0
(ION TRANSPORT
PROTEIN)		 5ah1 TRIACYLGLYCEROL
LIPASE
(Clostridium
botulinum) 		4 / 6 THR A 305
LEU A 308
MET A  87
LEU A 239
 None
 1.07A 6mvxA-5ah1A:
undetectable
6mvxB-5ah1A:
undetectable
6mvxC-5ah1A:
undetectable		 6mvxA-5ah1A:
20.75
6mvxB-5ah1A:
20.75
6mvxC-5ah1A:
20.75