SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ah4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		5 / 11 THR A  88
LEU A  84
VAL A  43
VAL A  67
VAL A  65
 None
 1.28A 1akdA-5ah4A:
undetectable		 1akdA-5ah4A:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EA1_A_TPFA470_1
(CYTOCHROME P450
51-LIKE RV0764C)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 8 PHE A 299
MET A 297
PHE A 333
LEU A 363
 None
 1.27A 1ea1A-5ah4A:
undetectable		 1ea1A-5ah4A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWJ_A_CAMA418_0
(CYTOCHROME P450-CAM)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		5 / 9 THR A  88
LEU A  84
VAL A  43
VAL A  67
VAL A  65
 None
 1.29A 1iwjA-5ah4A:
undetectable		 1iwjA-5ah4A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		5 / 10 THR A  88
LEU A  84
VAL A  43
VAL A  67
VAL A  65
 None
 1.30A 1o76A-5ah4A:
undetectable		 1o76A-5ah4A:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_B_FK5B401_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		5 / 10 LEU A 329
VAL A 322
ILE A 273
ILE A 282
PHE A 352
 NA  A1398 (-3.9A)
None
None
None
None
 1.29A 1q6iB-5ah4A:
undetectable		 1q6iB-5ah4A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_1
(POL POLYPROTEIN)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		5 / 11 LEU A 176
VAL A 202
GLY A 239
ILE A 240
VAL A 167
 None
 0.82A 1t7jA-5ah4A:
undetectable		 1t7jA-5ah4A:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 1.00A 1t85A-5ah4A:
undetectable		 1t85A-5ah4A:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		5 / 9 THR A  88
LEU A  84
VAL A  43
VAL A  67
VAL A  65
 None
 1.29A 1t86B-5ah4A:
undetectable		 1t86B-5ah4A:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 0.96A 1t87A-5ah4A:
undetectable		 1t87A-5ah4A:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 5 LYS A 283
ALA A 286
LEU A 306
SER A 307
 None
 1.07A 1tt6B-5ah4A:
undetectable		 1tt6B-5ah4A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 363
LEU A 342
LEU A 390
ALA A 361
ILE A 273
 None
 1.14A 1tw4A-5ah4A:
1.1		 1tw4A-5ah4A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 0.94A 1yrcA-5ah4A:
undetectable		 1yrcA-5ah4A:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 0.92A 1yrdA-5ah4A:
undetectable		 1yrdA-5ah4A:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 6 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 0.96A 2feuA-5ah4A:
undetectable		 2feuA-5ah4A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 0.96A 2feuB-5ah4A:
undetectable		 2feuB-5ah4A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ILE A 273
ALA A 271
MET A 297
ALA A 361
LEU A 338
 None
 1.05A 2h77A-5ah4A:
undetectable		 2h77A-5ah4A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 8 PHE A 299
LEU A 338
ALA A 361
ALA A 271
 None
 0.83A 2vcvP-5ah4A:
undetectable		 2vcvP-5ah4A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 6 THR A  88
LEU A  84
VAL A  43
VAL A  65
 None
 1.10A 2zuhA-5ah4A:
undetectable		 2zuhA-5ah4A:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 6 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 0.92A 2zuiA-5ah4A:
undetectable		 2zuiA-5ah4A:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 0.95A 2zwtA-5ah4A:
undetectable		 2zwtA-5ah4A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 0.94A 2zwuA-5ah4A:
undetectable		 2zwuA-5ah4A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_F_TOPF200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		5 / 10 ALA A 271
LEU A 304
ALA A 281
ILE A 282
LEU A 338
 None
 1.17A 3fl9F-5ah4A:
undetectable		 3fl9F-5ah4A:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 0.98A 3fwfA-5ah4A:
undetectable		 3fwfA-5ah4A:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 1.02A 3fwfB-5ah4A:
undetectable		 3fwfB-5ah4A:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 0.92A 3fwiA-5ah4A:
undetectable		 3fwiA-5ah4A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 0.97A 3fwjA-5ah4A:
undetectable		 3fwjA-5ah4A:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3003_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 6 ILE A 169
VAL A 167
LEU A 176
LEU A 189
 None
 0.71A 3kp6A-5ah4A:
undetectable
3kp6B-5ah4A:
undetectable		 3kp6A-5ah4A:
17.71
3kp6B-5ah4A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 0.99A 3l63A-5ah4A:
undetectable		 3l63A-5ah4A:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 6 GLU A 168
GLU A 188
PHE A 259
ALA A 177
 None
 1.12A 3pgyA-5ah4A:
undetectable
3pgyB-5ah4A:
undetectable		 3pgyA-5ah4A:
22.80
3pgyB-5ah4A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 0.97A 3wrhA-5ah4A:
undetectable		 3wrhA-5ah4A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 0.98A 3wrjA-5ah4A:
undetectable		 3wrjA-5ah4A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 0.95A 3wrlA-5ah4A:
undetectable		 3wrlA-5ah4A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_E_CAME503_0
(CAMPHOR
5-MONOOXYGENASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 1.01A 3wrlE-5ah4A:
undetectable		 3wrlE-5ah4A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 0.99A 3wrmA-5ah4A:
undetectable		 3wrmA-5ah4A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 0.98A 3wrmF-5ah4A:
undetectable		 3wrmF-5ah4A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 5 THR A 279
ILE A 282
LYS A 283
PHE A 352
 None
 1.47A 4ac9C-5ah4A:
undetectable		 4ac9C-5ah4A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 5 THR A 279
ILE A 282
LYS A 283
PHE A 352
 None
 1.50A 4acaC-5ah4A:
undetectable		 4acaC-5ah4A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 5 THR A 279
ILE A 282
LYS A 283
PHE A 352
 None
 1.48A 4acbC-5ah4A:
undetectable		 4acbC-5ah4A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		5 / 9 THR A  88
LEU A  84
VAL A  43
VAL A  67
VAL A  65
 None
 1.30A 4ek1B-5ah4A:
undetectable		 4ek1B-5ah4A:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 363
PHE A 352
ARG A 183
THR A 279
THR A 339
 None
 1.26A 4fiaA-5ah4A:
undetectable		 4fiaA-5ah4A:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 363
PHE A 352
ARG A 183
THR A 279
THR A 339
 None
 1.26A 4fiaA-5ah4A:
undetectable		 4fiaA-5ah4A:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 8 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 0.91A 4l4aA-5ah4A:
undetectable		 4l4aA-5ah4A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 0.96A 4l4gA-5ah4A:
undetectable		 4l4gA-5ah4A:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ILE A 165
ALA A 150
ALA A 212
LEU A 238
ILE A 240
 None
 1.07A 4lnwA-5ah4A:
undetectable		 4lnwA-5ah4A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ILE A 273
ALA A 271
MET A 297
ALA A 361
LEU A 338
 None
 1.12A 4lnwA-5ah4A:
undetectable		 4lnwA-5ah4A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ILE A 165
ALA A 150
ALA A 212
LEU A 238
ILE A 240
 None
 1.07A 4lnxA-5ah4A:
undetectable		 4lnxA-5ah4A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ILE A 273
ALA A 271
MET A 297
ALA A 361
LEU A 338
 None
 1.13A 4lnxA-5ah4A:
undetectable		 4lnxA-5ah4A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ALA A 269
ILE A 295
ALA A 332
MET A 297
PHE A 299
 NA  A1398 ( 4.2A)
None
None
None
None
 1.08A 4r29D-5ah4A:
undetectable		 4r29D-5ah4A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_B_ADNB902_1
(MYOSIN HEAVY CHAIN
KINASE A)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		5 / 10 PHE A  13
VAL A  15
LEU A  91
LEU A 107
THR A  88
 None
 1.19A 4zmeB-5ah4A:
undetectable		 4zmeB-5ah4A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 5 SER A 139
ARG A 246
GLY A 244
GLU A  64
 None
 1.13A 5cdqA-5ah4A:
undetectable
5cdqB-5ah4A:
undetectable
5cdqC-5ah4A:
undetectable		 5cdqA-5ah4A:
22.82
5cdqB-5ah4A:
19.75
5cdqC-5ah4A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 5 SER A 139
ARG A 246
GLY A 244
GLU A  64
 None
 1.13A 5cdqR-5ah4A:
undetectable
5cdqS-5ah4A:
undetectable
5cdqT-5ah4A:
undetectable		 5cdqR-5ah4A:
22.82
5cdqS-5ah4A:
19.75
5cdqT-5ah4A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		5 / 7 LEU A 162
THR A 179
PRO A 257
LEU A 389
MET A 391
 None
 0.82A 5fxtA-5ah4A:
36.5		 5fxtA-5ah4A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		6 / 8 THR A 179
LEU A 184
PRO A 257
PRO A 360
LEU A 389
MET A 391
 None
 0.50A 5g48A-5ah4A:
36.3		 5g48A-5ah4A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_B_1FLB1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		7 / 9 LEU A 162
THR A 179
LEU A 184
PRO A 257
PRO A 360
LEU A 389
MET A 391
 None
 0.63A 5g48B-5ah4A:
36.1		 5g48B-5ah4A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		5 / 11 VAL A 322
ILE A 273
ILE A 295
ILE A 282
PHE A 352
 None
 1.09A 5hw8D-5ah4A:
undetectable		 5hw8D-5ah4A:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 THR A  88
LEU A  84
VAL A  43
VAL A  67
 None
 0.99A 5wk9A-5ah4A:
undetectable		 5wk9A-5ah4A:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2T_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 8 PRO A 365
ALA A 381
THR A 384
ALA A 185
 None
 0.98A 5x2tI-5ah4A:
undetectable
5x2tJ-5ah4A:
undetectable
5x2tK-5ah4A:
undetectable
5x2tL-5ah4A:
undetectable		 5x2tI-5ah4A:
16.75
5x2tJ-5ah4A:
20.23
5x2tK-5ah4A:
16.75
5x2tL-5ah4A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_D_READ601_1
(RETINOIC ACID
RECEPTOR)		 5ah4 DNA POLYMERASE III
SUBUNIT BETA
(Mycolicibacteriu
m
smegmatis) 		4 / 7 LEU A  31
PHE A  20
LEU A  78
GLY A  42
 None
 0.78A 6eu9D-5ah4A:
undetectable		 6eu9D-5ah4A:
13.01