SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ahv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ILQ_C_ACAC7_1
(INTERLEUKIN-8
PRECURSOR
INTERLEUKIN-8
RECEPTOR A)		 5ahv ANTH DOMAIN OF
ENDOCYTIC ADAPTOR
SLA2
(Saccharomyces
cerevisiae) 		4 / 6 HIS F 232
ASP F 260
ASP F 263
PRO F 258
 None
 1.49A 1ilqA-5ahvF:
undetectable
1ilqC-5ahvF:
undetectable		 1ilqA-5ahvF:
14.61
1ilqC-5ahvF:
5.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 5ahv ANTH DOMAIN OF
ENDOCYTIC ADAPTOR
SLA2
ENTH DOMAIN OF EPSIN
ENT1
(Saccharomyces
cerevisiae) 		4 / 6 ILE F 188
VAL F 252
ILE E 102
ILE E  84
 None
 0.77A 1uwhA-5ahvF:
undetectable		 1uwhA-5ahvF:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_2
(MINERALOCORTICOID
RECEPTOR)		 5ahv ANTH DOMAIN OF
ENDOCYTIC ADAPTOR
SLA2
(Saccharomyces
cerevisiae) 		4 / 5 LEU F 105
LEU F  64
CYH F 182
THR F 180
 None
 1.26A 2oaxD-5ahvF:
undetectable		 2oaxD-5ahvF:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5ahv ANTH DOMAIN OF
ENDOCYTIC ADAPTOR
SLA2
(Saccharomyces
cerevisiae) 		4 / 6 PRO F 223
ILE F 152
ASN F 268
LEU F 205
 None
 1.29A 2wekB-5ahvF:
undetectable		 2wekB-5ahvF:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 5ahv ENTH DOMAIN OF EPSIN
ENT1
(Saccharomyces
cerevisiae) 		4 / 7 TYR E  82
ARG E  85
PHE E  86
ILE E  40
 None
 0.92A 2zseA-5ahvE:
undetectable		 2zseA-5ahvE:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 5ahv ENTH DOMAIN OF EPSIN
ENT1
(Saccharomyces
cerevisiae) 		4 / 8 LEU E  42
SER E  46
ASP E  81
TYR E  82
 None
 1.06A 4drjB-5ahvE:
2.4		 4drjB-5ahvE:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 5ahv ANTH DOMAIN OF
ENDOCYTIC ADAPTOR
SLA2
(Saccharomyces
cerevisiae) 		4 / 7 ILE F  89
VAL F 110
ILE F 106
GLU F  57
 None
 0.94A 4zzbC-5ahvF:
2.3
4zzbD-5ahvF:
2.3		 4zzbC-5ahvF:
24.26
4zzbD-5ahvF:
24.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ahv ENTH DOMAIN OF EPSIN
ENT1
(Saccharomyces
cerevisiae) 		4 / 8 ASP E  81
THR E  78
HIS E  32
LEU E  83
 None
 1.19A 5b1bA-5ahvE:
undetectable
5b1bC-5ahvE:
undetectable
5b1bP-5ahvE:
undetectable		 5b1bA-5ahvE:
12.86
5b1bC-5ahvE:
18.08
5b1bP-5ahvE:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_B_ADNB302_1
(FLUORINASE)		 5ahv ANTH DOMAIN OF
ENDOCYTIC ADAPTOR
SLA2
(Saccharomyces
cerevisiae) 		4 / 6 TRP F  36
THR F  35
TYR F  34
SER F  41
 None
 1.46A 5b6iB-5ahvF:
undetectable		 5b6iB-5ahvF:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		 5ahv ANTH DOMAIN OF
ENDOCYTIC ADAPTOR
SLA2
(Saccharomyces
cerevisiae) 		5 / 11 LEU F 221
MET F 208
MET F 204
SER F 143
GLY F 217
 None
 1.20A 5g6sA-5ahvF:
undetectable
5g6sG-5ahvF:
undetectable		 5g6sA-5ahvF:
22.40
5g6sG-5ahvF:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		 5ahv ANTH DOMAIN OF
ENDOCYTIC ADAPTOR
SLA2
(Saccharomyces
cerevisiae) 		5 / 12 MET F 204
SER F 143
GLY F 217
LEU F 221
MET F 208
 None
 1.20A 5g6sB-5ahvF:
undetectable
5g6sC-5ahvF:
undetectable		 5g6sB-5ahvF:
22.40
5g6sC-5ahvF:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		 5ahv ANTH DOMAIN OF
ENDOCYTIC ADAPTOR
SLA2
(Saccharomyces
cerevisiae) 		5 / 10 SER F 143
GLY F 217
VAL F 140
LEU F 221
MET F 208
 None
 1.46A 5g6sD-5ahvF:
undetectable
5g6sF-5ahvF:
undetectable		 5g6sD-5ahvF:
22.40
5g6sF-5ahvF:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 5ahv ANTH DOMAIN OF
ENDOCYTIC ADAPTOR
SLA2
(Saccharomyces
cerevisiae) 		4 / 5 TYR F 228
LYS F 225
LEU F 230
GLU F 229
 None
 1.33A 5weaA-5ahvF:
undetectable		 5weaA-5ahvF:
15.35