SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5aih'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZP4_B_C2FB996_0 (5,10-METHYLENETETRAH YDROFOLATE REDUCTASE)	5aih	LIMONENE-1,2-EPOXIDE HYDROLASE (unidentified)	5 / 10	ASP A 82 SER A 106 THR A 78 LEU A 26 ARG A 43	None None None None DMS A 202 (-3.8A)	1.29A	1zp4B-5aihA: 0.0	1zp4B-5aihA: 18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V2O_B_CLQB1079_0 (SAPOSIN-B)	5aih	LIMONENE-1,2-EPOXIDE HYDROLASE (unidentified)	3 / 3	MET A 1 GLU A 5 LEU A 9	None	0.79A	4v2oB-5aihA: undetectable	4v2oB-5aihA: 24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WK9_A_CAMA503_0 (CAMPHOR 5-MONOOXYGENASE)	5aih	LIMONENE-1,2-EPOXIDE HYDROLASE (unidentified)	4 / 7	TYR A 32 LEU A 50 VAL A 96 ASP A 112	None DMS A 203 (-4.7A) None DMS A 201 ( 4.8A)	1.05A	5wk9A-5aihA: undetectable	5wk9A-5aihA: 17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWD_B_GLYB709_0 (DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1)	5aih	LIMONENE-1,2-EPOXIDE HYDROLASE (unidentified)	4 / 5	GLY A 21 ASP A 20 ARG A 43 ARG A 47	None EDO A 304 ( 2.8A) DMS A 202 (-3.8A) EDO A 304 (-4.5A)	1.17A	6dwdB-5aihA: undetectable 6dwdD-5aihA: undetectable	6dwdB-5aihA: 13.41 6dwdD-5aihA: 13.41

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ZP4_B_C2FB996_0","5,10-METHYLENETETRAHYDROFOLATE REDUCTASE","5aih","LIMONENE-1,2-EPOXIDE HYDROLASE","unidentified",5,"ASP A  82;SER A 106;THR A  78;LEU A  26;ARG A  43","None;None;None;None;DMS A 202 (-3.8A)","1.29A","1zp4B-5aihA:0.0","1zp4B-5aihA:18.21"],["4V2O_B_CLQB1079_0","SAPOSIN-B","5aih","LIMONENE-1,2-EPOXIDE HYDROLASE","unidentified",3,"MET A   1;GLU A   5;LEU A   9","None","0.79A","4v2oB-5aihA:undetectable","4v2oB-5aihA:24.32"],["5WK9_A_CAMA503_0","CAMPHOR 5-MONOOXYGENASE","5aih","LIMONENE-1,2-EPOXIDE HYDROLASE","unidentified",4,"TYR A  32;LEU A  50;VAL A  96;ASP A 112","None;DMS A 203 (-4.7A);None;DMS A 201 ( 4.8A)","1.05A","5wk9A-5aihA:undetectable","5wk9A-5aihA:17.27"],["6DWD_B_GLYB709_0","DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE SAMHD1","5aih","LIMONENE-1,2-EPOXIDE HYDROLASE","unidentified",4,"GLY A  21;ASP A  20;ARG A  43;ARG A  47","None;EDO A 304 ( 2.8A);DMS A 202 (-3.8A);EDO A 304 (-4.5A)","1.17A","6dwdB-5aihA:undetectable;6dwdD-5aihA:undetectable","6dwdB-5aihA:13.41;6dwdD-5aihA:13.41"]]