SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ail'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)		 5ail POLY [ADP-RIBOSE]
POLYMERASE 9
(Homo
sapiens) 		4 / 8 GLY A 311
PHE A 431
PHE A 444
GLY A 398
 None
 0.88A 3ko0O-5ailA:
undetectable
3ko0Q-5ailA:
undetectable		 3ko0O-5ailA:
19.13
3ko0Q-5ailA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 5ail POLY [ADP-RIBOSE]
POLYMERASE 9
(Homo
sapiens) 		4 / 7 GLY A 398
GLY A 311
PHE A 431
PHE A 444
 None
 0.88A 3ko0M-5ailA:
undetectable
3ko0P-5ailA:
undetectable		 3ko0M-5ailA:
19.13
3ko0P-5ailA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNE_G_ACTG601_0
(CHOLINE OXIDASE)		 5ail POLY [ADP-RIBOSE]
POLYMERASE 9
(Homo
sapiens) 		4 / 6 ALA A 321
ILE A 317
HIS A 358
ASN A 301
 None
 1.15A 3nneG-5ailA:
undetectable		 3nneG-5ailA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 5ail POLY [ADP-RIBOSE]
POLYMERASE 9
(Homo
sapiens) 		4 / 5 ILE A 286
ILE A 440
TYR A 441
GLU A 439
 None
 1.13A 4a99D-5ailA:
undetectable		 4a99D-5ailA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_B_QPSB951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 5ail POLY [ADP-RIBOSE]
POLYMERASE 9
(Homo
sapiens) 		4 / 8 GLU A 405
GLU A 447
LYS A 450
ARG A 451
 EDO  A1458 (-2.5A)
None
None
None
 1.18A 4bqfB-5ailA:
3.9		 4bqfB-5ailA:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_B_PQNB1844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5ail POLY [ADP-RIBOSE]
POLYMERASE 9
(Homo
sapiens) 		5 / 10 MET A 448
PHE A 412
SER A 445
ALA A 394
ALA A 408
 None
 1.43A 5oy0b-5ailA:
undetectable		 5oy0b-5ailA:
18.60