SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5aim'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OT7_B_IU5B1002_1
(BILE ACID RECEPTOR)		 5aim TRANSCRIPTION FACTOR
TAU 138 KDA SUBUNIT
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 608
ARG A 573
PHE A 576
ILE A 559
TYR A 577
 None
 1.44A 1ot7B-5aimA:
undetectable		 1ot7B-5aimA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA502_0
(FERROCHELATASE)		 5aim TRANSCRIPTION FACTOR
TAU 138 KDA SUBUNIT
(Saccharomyces
cerevisiae) 		4 / 8 ARG A 633
SER A 579
GLY A 567
MET A 563
 None
 1.11A 2qd3A-5aimA:
undetectable		 2qd3A-5aimA:
15.34