SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5aip'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 5aip TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY
(Neisseria
meningitidis) 		5 / 12 LEU A  71
GLY A  69
LEU A  67
ILE A  41
ASP A  36
 None
 0.85A 3gwvA-5aipA:
undetectable		 3gwvA-5aipA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)		 5aip TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY
(Neisseria
meningitidis) 		5 / 12 LEU A  71
GLY A  69
LEU A  67
ILE A  41
ASP A  36
 None
 0.87A 3gwwA-5aipA:
2.0		 3gwwA-5aipA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5aip TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY
(Neisseria
meningitidis) 		4 / 7 ASP A 112
ARG A  43
TYR A 104
GLU A  47
 None
 1.12A 6mn5B-5aipA:
undetectable		 6mn5B-5aipA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5aip TRANSCRIPTIONAL
REGULATOR, MARR
FAMILY
(Neisseria
meningitidis) 		4 / 7 ASP A 112
ARG A  43
TYR A 104
GLU A  47
 None
 1.08A 6mn5E-5aipA:
undetectable		 6mn5E-5aipA:
19.86