SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5aiw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 5aiw TRAH
(Enterococcus
faecalis) 		4 / 7 PHE A  70
LEU A 101
THR A  73
TYR A  75
 None
 1.23A 1rmtB-5aiwA:
undetectable		 1rmtB-5aiwA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5aiw TRAH
(Enterococcus
faecalis) 		4 / 8 GLN A 150
PHE A  70
ILE A 128
VAL A 144
 None
 0.96A 4dx7B-5aiwA:
undetectable		 4dx7B-5aiwA:
8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME
KP18CYS PEPTIDE)		 5aiw TRAH
(Enterococcus
faecalis) 		5 / 12 GLU A 134
GLN A 141
LEU A 164
ILE A 178
LEU A 180
 None
 1.49A 4k38A-5aiwA:
undetectable
4k38D-5aiwA:
undetectable		 4k38A-5aiwA:
17.20
4k38D-5aiwA:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 5aiw TRAH
(Enterococcus
faecalis) 		3 / 3 TYR A 111
TYR A  77
GLN A 119
 None
 1.07A 5jsdA-5aiwA:
undetectable
5jsdB-5aiwA:
undetectable		 5jsdA-5aiwA:
11.34
5jsdB-5aiwA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 5aiw TRAH
(Enterococcus
faecalis) 		3 / 3 TYR A 111
TYR A  77
GLN A 119
 None
 1.08A 5jsdB-5aiwA:
undetectable
5jsdC-5aiwA:
undetectable		 5jsdB-5aiwA:
11.34
5jsdC-5aiwA:
11.34