SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5aiz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5aiz ZINC FINGER MIZ
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 8 LYS A  19
LEU A  22
GLN A  23
PHE A  28
 None
 0.89A 1v54C-5aizA:
undetectable
1v54J-5aizA:
undetectable		 1v54C-5aizA:
18.60
1v54J-5aizA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5aiz ZINC FINGER MIZ
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 8 LYS A  19
LEU A  22
GLN A  23
PHE A  28
 None
 0.89A 2dyrC-5aizA:
undetectable
2dyrJ-5aizA:
undetectable		 2dyrC-5aizA:
18.60
2dyrJ-5aizA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 5aiz ZINC FINGER MIZ
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 GLY A  74
ALA A  64
VAL A  63
ASN A  24
PHE A  28
 None
 1.13A 4pd5A-5aizA:
2.2		 4pd5A-5aizA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_B_RTLB201_0
(RETINOL-BINDING
PROTEIN 2)		 5aiz ZINC FINGER MIZ
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		5 / 12 PHE A  45
ARG A  85
LEU A  96
LEU A  35
LEU A  53
 None
 1.49A 4qynB-5aizA:
undetectable		 4qynB-5aizA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5aiz ZINC FINGER MIZ
DOMAIN-CONTAINING
PROTEIN 1
(Homo
sapiens) 		4 / 8 HIS A  29
LEU A  36
THR A  33
ALA A  32
 ACT  A1114 (-4.3A)
None
ACT  A1114 ( 4.3A)
None
 0.90A 5tt3H-5aizA:
undetectable		 5tt3H-5aizA:
19.91