SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ajh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 5ajh CUTINASE
(Fusarium
oxysporum) 		4 / 7 SER A  93
LEU A  87
PRO A  88
ASP A 133
 None
 0.96A 2ddwB-5ajhA:
undetectable		 2ddwB-5ajhA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		 5ajh CUTINASE
(Fusarium
oxysporum) 		5 / 12 GLY A  47
GLY A  75
ARG A  21
ALA A  25
ASP A  23
 None
None
None
MPD  A1219 ( 4.0A)
None
 1.02A 3keeD-5ajhA:
undetectable		 3keeD-5ajhA:
25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5ajh CUTINASE
(Fusarium
oxysporum) 		4 / 8 ASN A  48
LEU A 126
HIS A 102
ASN A  22
 None
None
None
MPD  A1219 (-3.6A)
 1.13A 3kp2A-5ajhA:
undetectable
3kp2B-5ajhA:
undetectable		 3kp2A-5ajhA:
20.45
3kp2B-5ajhA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SM2_A_478A126_2
(GAG-PRO-POL
POLYPROTEIN)		 5ajh CUTINASE
(Fusarium
oxysporum) 		5 / 11 VAL A  56
VAL A 146
GLY A 144
ALA A 143
LEU A  60
 None
 0.98A 3sm2B-5ajhA:
undetectable		 3sm2B-5ajhA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 5ajh CUTINASE
(Fusarium
oxysporum) 		4 / 8 PHE A 148
HIS A 189
GLY A 149
GLY A  50
 None
MPD  A1221 (-4.0A)
None
None
 0.88A 3v3nB-5ajhA:
2.8		 3v3nB-5ajhA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 5ajh CUTINASE
(Fusarium
oxysporum) 		4 / 8 PHE A 148
HIS A 189
GLY A 149
GLY A  50
 None
MPD  A1221 (-4.0A)
None
None
 0.88A 3v3nC-5ajhA:
2.8		 3v3nC-5ajhA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_F_SAMF301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5ajh CUTINASE
(Fusarium
oxysporum) 		5 / 12 ALA A 196
GLN A 122
PHE A 148
GLY A  42
SER A  43
 None
None
None
MPD  A1221 (-3.6A)
MPD  A1221 (-4.7A)
 1.27A 5hfjF-5ajhA:
2.4		 5hfjF-5ajhA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5ajh CUTINASE
(Fusarium
oxysporum) 		4 / 6 LYS A  59
LEU A  60
PHE A  37
LEU A 204
 None
 1.19A 5x19P-5ajhA:
undetectable		 5x19P-5ajhA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ajh CUTINASE
(Fusarium
oxysporum) 		4 / 5 ILE A  71
PHE A  37
ARG A  41
THR A  51
 None
 1.27A 5z84N-5ajhA:
undetectable
5z84W-5ajhA:
undetectable		 5z84N-5ajhA:
18.34
5z84W-5ajhA:
16.23