SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5aju'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5aju PHOSPHORIBOHYDROLASE
LONELY GUY
(Claviceps
purpurea) 		5 / 12 ILE A 177
TRP A 167
VAL A 139
ALA A 136
ILE A 140
 None
 0.91A 1epbB-5ajuA:
undetectable		 1epbB-5ajuA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 5aju PHOSPHORIBOHYDROLASE
LONELY GUY
(Claviceps
purpurea) 		4 / 7 ILE A 165
LEU A 179
GLY A 150
TYR A 185
 None
 0.87A 4iqqB-5ajuA:
undetectable		 4iqqB-5ajuA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJQ_A_27RA401_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5aju PHOSPHORIBOHYDROLASE
LONELY GUY
(Claviceps
purpurea) 		4 / 5 ARG A  96
THR A  66
PRO A 114
VAL A 118
 SO4  A1242 (-2.6A)
None
None
None
 1.23A 4mjqA-5ajuA:
undetectable		 4mjqA-5ajuA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5aju PHOSPHORIBOHYDROLASE
LONELY GUY
(Claviceps
purpurea) 		5 / 12 VAL A  77
GLY A  88
TYR A 119
ILE A  89
ILE A  90
 None
 1.46A 4xucA-5ajuA:
undetectable		 4xucA-5ajuA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 5aju PHOSPHORIBOHYDROLASE
LONELY GUY
(Claviceps
purpurea) 		4 / 7 GLU A  55
GLU A 217
ASP A 215
ALA A 216
 None
 1.15A 4zz8A-5ajuA:
undetectable		 4zz8A-5ajuA:
22.86