SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5amo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5amo NOELIN
(Mus
musculus) 		4 / 5 THR A 422
THR A 415
GLU A 404
HIS A 448
 None
 1.44A 1d4fB-5amoA:
undetectable		 1d4fB-5amoA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 5amo NOELIN
(Mus
musculus) 		5 / 12 ILE A 440
TYR A 397
ILE A 377
ALA A 402
THR A 422
 None
 1.11A 1jtxA-5amoA:
undetectable		 1jtxA-5amoA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_B_SAMB302_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 5amo NOELIN
(Mus
musculus) 		4 / 5 SER A 353
ASP A 453
ASP A 360
ILE A 407
 None
 1.40A 3uj7B-5amoA:
undetectable		 3uj7B-5amoA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5amo NOELIN
(Mus
musculus) 		3 / 3 SER A 353
ASP A 453
ASP A 360
 None
 0.90A 4mwzA-5amoA:
undetectable		 4mwzA-5amoA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 5amo NOELIN
(Mus
musculus) 		4 / 8 SER A 242
GLY A 243
ILE A 449
GLY A 247
 None
 0.71A 5alcL-5amoA:
undetectable		 5alcL-5amoA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_C_URFC301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 5amo NOELIN
(Mus
musculus) 		3 / 3 ARG A 293
HIS A 296
ARG A 272
 None
 0.93A 5iaoC-5amoA:
undetectable		 5iaoC-5amoA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IAO_F_URFF301_1
(BIFUNCTIONAL PROTEIN
PYRR)		 5amo NOELIN
(Mus
musculus) 		3 / 3 ARG A 293
HIS A 296
ARG A 272
 None
 0.93A 5iaoF-5amoA:
undetectable		 5iaoF-5amoA:
18.26