SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5amw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 5amw FRA A 2 ALLERGEN
(Fragaria
x
ananassa) 		6 / 12 PHE A  23
ILE A  57
TYR A  82
TYR A  84
ILE A  99
LEU A 144
 None
 0.81A 1fm4A-5amwA:
24.5		 1fm4A-5amwA:
55.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 5amw FRA A 2 ALLERGEN
(Fragaria
x
ananassa) 		6 / 12 PHE A  23
TYR A  82
TYR A  84
ILE A  99
TYR A 121
LEU A 144
 None
 0.69A 1fm4A-5amwA:
24.5		 1fm4A-5amwA:
55.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5amw FRA A 2 ALLERGEN
(Fragaria
x
ananassa) 		3 / 3 THR A   8
SER A 142
LYS A 146
 None
 1.21A 3aocC-5amwA:
undetectable		 3aocC-5amwA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 5amw FRA A 2 ALLERGEN
(Fragaria
x
ananassa) 		4 / 4 LEU A 147
ALA A  38
VAL A  39
PRO A  36
 None
 1.04A 3gv1B-5amwA:
undetectable		 3gv1B-5amwA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP6_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 5amw FRA A 2 ALLERGEN
(Fragaria
x
ananassa) 		5 / 12 PHE A  59
TYR A 101
VAL A 148
HIS A  70
VAL A  68
 None
 1.28A 3sp6A-5amwA:
undetectable		 3sp6A-5amwA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP6_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 5amw FRA A 2 ALLERGEN
(Fragaria
x
ananassa) 		5 / 12 PHE A  59
TYR A 101
VAL A 148
ILE A  57
HIS A  70
 None
 1.22A 3sp6A-5amwA:
undetectable		 3sp6A-5amwA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U88_A_CHDA611_0
(MENIN)		 5amw FRA A 2 ALLERGEN
(Fragaria
x
ananassa) 		3 / 3 SER A 107
PHE A  80
LYS A 104
 None
 0.91A 3u88A-5amwA:
undetectable		 3u88A-5amwA:
14.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5amw FRA A 2 ALLERGEN
(Fragaria
x
ananassa) 		6 / 12 ILE A  24
ASP A  28
ILE A  57
VAL A  68
TYR A  82
LEU A 144
 None
 0.81A 4a81A-5amwA:
24.6		 4a81A-5amwA:
58.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5amw FRA A 2 ALLERGEN
(Fragaria
x
ananassa) 		5 / 12 ILE A  24
ASP A  28
LYS A  55
TYR A  82
LEU A 144
 None
 0.79A 4a81A-5amwA:
24.6		 4a81A-5amwA:
58.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5amw FRA A 2 ALLERGEN
(Fragaria
x
ananassa) 		5 / 12 ASP A  28
ILE A  57
TYR A  82
TYR A  84
LEU A 144
 None
 0.82A 4a84A-5amwA:
24.3		 4a84A-5amwA:
58.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5amw FRA A 2 ALLERGEN
(Fragaria
x
ananassa) 		6 / 12 ASP A  28
TYR A  82
TYR A  84
ILE A  99
TYR A 121
LEU A 144
 None
 0.81A 4a84A-5amwA:
24.3		 4a84A-5amwA:
58.49