SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5an1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5an1 GLUTATHIONE
S-TRANSFERASE
(Litopenaeus
vannamei) 		4 / 8 ARG A  11
TYR A   7
GLU A 160
HIS A 165
 None
 1.07A 1nx9A-5an1A:
undetectable		 1nx9A-5an1A:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5an1 GLUTATHIONE
S-TRANSFERASE
(Litopenaeus
vannamei) 		4 / 8 TYR A 125
GLU A 109
SER A  73
TYR A   7
 None
None
GSH  A1220 (-2.7A)
None
 1.11A 1nx9A-5an1A:
undetectable		 1nx9A-5an1A:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5an1 GLUTATHIONE
S-TRANSFERASE
(Litopenaeus
vannamei) 		4 / 8 ARG A  11
TYR A   7
GLU A 160
HIS A 165
 None
 1.08A 1nx9B-5an1A:
undetectable		 1nx9B-5an1A:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5an1 GLUTATHIONE
S-TRANSFERASE
(Litopenaeus
vannamei) 		4 / 8 ARG A  11
TYR A   7
GLU A 160
HIS A 165
 None
 1.07A 1nx9C-5an1A:
undetectable		 1nx9C-5an1A:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5an1 GLUTATHIONE
S-TRANSFERASE
(Litopenaeus
vannamei) 		4 / 8 TYR A 125
GLU A 109
SER A  73
TYR A   7
 None
None
GSH  A1220 (-2.7A)
None
 1.12A 1nx9C-5an1A:
undetectable		 1nx9C-5an1A:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5an1 GLUTATHIONE
S-TRANSFERASE
(Litopenaeus
vannamei) 		4 / 8 ARG A  11
TYR A   7
GLU A 160
HIS A 165
 None
 1.06A 1nx9D-5an1A:
undetectable		 1nx9D-5an1A:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)		 5an1 GLUTATHIONE
S-TRANSFERASE
(Litopenaeus
vannamei) 		4 / 8 TYR A 125
GLU A 109
SER A  73
TYR A   7
 None
None
GSH  A1220 (-2.7A)
None
 1.12A 1nx9D-5an1A:
undetectable		 1nx9D-5an1A:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 5an1 GLUTATHIONE
S-TRANSFERASE
(Litopenaeus
vannamei) 		3 / 3 THR A 113
LYS A  50
GLU A 109
 None
GSH  A1220 (-3.6A)
None
 1.00A 3ijdB-5an1A:
undetectable		 3ijdB-5an1A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 5an1 GLUTATHIONE
S-TRANSFERASE
(Litopenaeus
vannamei) 		3 / 3 TYR A 119
MET A 107
LEU A 129
 None
 0.91A 3vw1D-5an1A:
undetectable		 3vw1D-5an1A:
23.04