SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5an3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		 5an3 SGT1
(Saccharomyces
cerevisiae) 		4 / 7 TYR A  94
ASP A  72
GLU A  69
PHE A  98
 None
 1.22A 1b2iA-5an3A:
undetectable		 1b2iA-5an3A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5an3 SUPPRESSOR OF
KINETOCHORE PROTEIN
1
(Saccharomyces
cerevisiae) 		4 / 6 PHE D 123
HIS D  97
ALA D 149
GLY D 150
 None
 1.14A 1l7xA-5an3D:
undetectable		 1l7xA-5an3D:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5an3 SUPPRESSOR OF
KINETOCHORE PROTEIN
1
(Saccharomyces
cerevisiae) 		4 / 6 PHE D 123
HIS D  97
ALA D 149
GLY D 150
 None
 1.12A 1l7xB-5an3D:
undetectable		 1l7xB-5an3D:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 5an3 SUPPRESSOR OF
KINETOCHORE PROTEIN
1
(Saccharomyces
cerevisiae) 		5 / 10 LEU D   8
ILE D  22
SER D  26
LEU D 146
ALA D  94
 None
 1.04A 5l0zB-5an3D:
undetectable		 5l0zB-5an3D:
17.22