SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5anr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 5anr PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX6
(Homo
sapiens) 		4 / 8 PHE B 377
ILE B 400
GLY B 383
PHE B 380
 None
 0.86A 1rtsA-5anrB:
undetectable		 1rtsA-5anrB:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 5anr PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX6
(Homo
sapiens) 		3 / 3 LYS B 413
ARG B 421
LYS B 367
 None
 1.15A 3okxA-5anrB:
undetectable		 3okxA-5anrB:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF411_0
(PROTEIN (ARGINASE))		 5anr PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX6
(Homo
sapiens) 		4 / 6 ARG B 421
HIS B 420
LEU B 414
ASP B 392
 None
 1.45A 4cevE-5anrB:
5.6
4cevF-5anrB:
5.3		 4cevE-5anrB:
23.12
4cevF-5anrB:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDA_A_RLTA403_1
(MARINER MOS1
TRANSPOSASE)		 5anr PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX6
(Homo
sapiens) 		4 / 6 ASN B 299
ALA B 138
TYR B 276
ASP B 249
 None
 1.18A 4mdaA-5anrB:
undetectable		 4mdaA-5anrB:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OU1_A_BEZA302_0
(RETRO-ALDOLASE,
DESIGN RA114)		 5anr PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX6
(Homo
sapiens) 		4 / 8 TYR B 276
ILE B 298
ILE B 136
ALA B 130
 None
 0.95A 4ou1A-5anrB:
undetectable		 4ou1A-5anrB:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 5anr PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX6
(Homo
sapiens) 		5 / 10 ILE B 243
MET B 168
ILE B 263
ILE B 230
ILE B 226
 None
 1.08A 5murE-5anrB:
undetectable		 5murE-5anrB:
14.48