SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5aog'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5aog CATIONIC PEROXIDASE
SPC4
(Sorghum
bicolor) 		4 / 4 SER A 153
GLY A 154
HIS A  79
ASP A 140
 None
 1.31A 2oxtC-5aogA:
undetectable		 2oxtC-5aogA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 5aog CATIONIC PEROXIDASE
SPC4
(Sorghum
bicolor) 		3 / 3 LEU A  93
VAL A 136
ARG A 330
 None
 0.90A 3b0wB-5aogA:
undetectable		 3b0wB-5aogA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5aog CATIONIC PEROXIDASE
SPC4
(Sorghum
bicolor) 		5 / 12 LEU A 142
GLY A  74
GLY A 214
ALA A 146
ILE A 213
 None
HEM  A1341 (-3.6A)
HEM  A1341 (-3.4A)
None
None
 1.03A 3ku1H-5aogA:
undetectable		 3ku1H-5aogA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5aog CATIONIC PEROXIDASE
SPC4
(Sorghum
bicolor) 		5 / 12 PHE A  80
ILE A 197
ALA A 171
GLY A 179
LEU A 180
 HEM  A1341 (-3.4A)
None
None
None
GOL  A1344 ( 4.3A)
 1.02A 4e1gA-5aogA:
undetectable		 4e1gA-5aogA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_B_LNLB701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5aog CATIONIC PEROXIDASE
SPC4
(Sorghum
bicolor) 		5 / 12 PHE A  80
ILE A 197
ALA A 171
GLY A 179
LEU A 180
 HEM  A1341 (-3.4A)
None
None
None
GOL  A1344 ( 4.3A)
 1.05A 4e1gB-5aogA:
1.4		 4e1gB-5aogA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_B_ACTB1001_0
(FORMIN-LIKE PROTEIN
3)		 5aog CATIONIC PEROXIDASE
SPC4
(Sorghum
bicolor) 		4 / 4 VAL A 270
ASN A 266
ASN A 271
ARG A 259
 None
None
None
NAG  A1347 ( 4.8A)
 1.29A 4eahB-5aogA:
0.0
4eahC-5aogA:
0.0		 4eahB-5aogA:
22.33
4eahC-5aogA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 5aog CATIONIC PEROXIDASE
SPC4
(Sorghum
bicolor) 		4 / 7 ALA A  73
LEU A  75
SER A 149
SER A 153
 HEM  A1341 (-3.7A)
None
None
None
 0.96A 4iklA-5aogA:
undetectable
4iklB-5aogA:
undetectable		 4iklA-5aogA:
16.56
4iklB-5aogA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 5aog CATIONIC PEROXIDASE
SPC4
(Sorghum
bicolor) 		4 / 8 SER A 153
ALA A  73
LEU A  75
SER A 149
 None
HEM  A1341 (-3.7A)
None
None
 0.97A 4iklA-5aogA:
undetectable
4iklB-5aogA:
undetectable		 4iklA-5aogA:
16.56
4iklB-5aogA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C6P_A_4YHA601_1
(PROTEIN C)		 5aog CATIONIC PEROXIDASE
SPC4
(Sorghum
bicolor) 		4 / 6 ALA A 206
GLN A 302
SER A 301
ASP A 307
 None
 1.14A 5c6pA-5aogA:
undetectable		 5c6pA-5aogA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 5aog CATIONIC PEROXIDASE
SPC4
(Sorghum
bicolor) 		4 / 8 SER A 137
ASP A 140
PHE A  45
SER A  42
 None
 1.12A 5l1fA-5aogA:
undetectable
5l1fB-5aogA:
undetectable		 5l1fA-5aogA:
16.38
5l1fB-5aogA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 5aog CATIONIC PEROXIDASE
SPC4
(Sorghum
bicolor) 		5 / 12 VAL A 176
LEU A 142
HIS A  81
GLY A  96
LEU A  94
 None
 1.31A 5m50E-5aogA:
undetectable		 5m50E-5aogA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_0
(REGULATORY PROTEIN
TETR)		 5aog CATIONIC PEROXIDASE
SPC4
(Sorghum
bicolor) 		5 / 12 ALA A 206
GLY A 209
SER A 208
LEU A 285
ASP A 257
 None
None
None
None
CA  A1342 (-3.2A)
 1.50A 5vlmF-5aogA:
undetectable		 5vlmF-5aogA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 5aog CATIONIC PEROXIDASE
SPC4
(Sorghum
bicolor) 		4 / 7 LEU A  94
ASP A  89
ARG A 330
GLN A  86
 None
NA  A1343 (-3.1A)
None
None
 1.17A 6g31D-5aogA:
undetectable		 6g31D-5aogA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 5aog CATIONIC PEROXIDASE
SPC4
(Sorghum
bicolor) 		3 / 3 ASP A  68
SER A 149
SER A 153
 None
 0.74A 6mxtA-5aogA:
undetectable		 6mxtA-5aogA:
20.49