SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5aoh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MSK_A_SAMA1301_0
(COBALAMIN-DEPENDENT
METHIONINE SYNTHASE)		 5aoh CARF
(Serratia
sp.
ATCC
39006) 		5 / 10 ASP A 129
PRO A 136
PRO A 110
ALA A 138
TYR A 111
 None
 1.46A 1mskA-5aohA:
undetectable		 1mskA-5aohA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 5aoh CARF
(Serratia
sp.
ATCC
39006) 		4 / 4 VAL A  90
ALA A  95
LEU A 261
PHE A  98
 None
 1.23A 1q97B-5aohA:
undetectable		 1q97B-5aohA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5aoh CARF
(Serratia
sp.
ATCC
39006) 		5 / 12 LEU A 242
ALA A 147
LEU A  34
ARG A 142
LEU A 202
 None
 1.20A 1s9pB-5aohA:
undetectable		 1s9pB-5aohA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 5aoh CARF
(Serratia
sp.
ATCC
39006) 		5 / 9 LEU A 261
PHE A 259
LEU A 102
HIS A 106
LEU A  52
 None
 1.36A 2bxeA-5aohA:
undetectable		 2bxeA-5aohA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)		 5aoh CARF
(Serratia
sp.
ATCC
39006) 		4 / 7 MET A  40
VAL A  10
PHE A  37
ARG A 263
 None
 1.12A 2kotA-5aohA:
undetectable		 2kotA-5aohA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5aoh CARF
(Serratia
sp.
ATCC
39006) 		5 / 12 LEU A 146
LEU A 242
ALA A 243
ILE A  39
LEU A  34
 None
 1.00A 3h0aA-5aohA:
undetectable		 3h0aA-5aohA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5aoh CARF
(Serratia
sp.
ATCC
39006) 		5 / 12 ALA A 153
ALA A 152
LEU A 242
ALA A 170
LEU A  34
 None
 1.11A 4nqaH-5aohA:
undetectable		 4nqaH-5aohA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA205_0
(OXIDOREDUCTASE)		 5aoh CARF
(Serratia
sp.
ATCC
39006) 		4 / 5 SER A 241
GLY A 240
ARG A 168
PHE A  21
 None
 0.84A 4r82A-5aohA:
undetectable
4r82B-5aohA:
undetectable		 4r82A-5aohA:
23.13
4r82B-5aohA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5aoh CARF
(Serratia
sp.
ATCC
39006) 		4 / 4 GLY A  65
VAL A  87
PHE A 230
ILE A 257
 None
 1.13A 4xv2B-5aohA:
0.7		 4xv2B-5aohA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5aoh CARF
(Serratia
sp.
ATCC
39006) 		5 / 11 LEU A 242
GLY A 232
GLY A 209
SER A 167
ALA A 153
 None
None
K  A1267 (-4.4A)
None
None
 0.95A 5o96G-5aohA:
undetectable		 5o96G-5aohA:
19.71