SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5aox'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_B_ACTB704_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		3 / 3 ARG B  21
GLY B  93
ASP B  92
 None
 0.58A 1kf6A-5aoxB:
2.0
1kf6B-5aoxB:
undetectable		 1kf6A-5aoxB:
10.24
1kf6B-5aoxB:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 6 GLU B  12
ALA B  60
LEU B  58
VAL B  26
 None
 0.78A 1sn5A-5aoxB:
undetectable		 1sn5A-5aoxB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 8 GLU B  12
ALA B  60
LEU B  58
VAL B  26
 None
 0.76A 1sn5C-5aoxB:
undetectable		 1sn5C-5aoxB:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 8 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.84A 1v54C-5aoxB:
undetectable
1v54J-5aoxB:
undetectable		 1v54C-5aoxB:
17.86
1v54J-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 8 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.83A 1v54P-5aoxB:
undetectable
1v54W-5aoxB:
undetectable		 1v54P-5aoxB:
17.86
1v54W-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 8 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.84A 2dyrC-5aoxB:
undetectable
2dyrJ-5aoxB:
undetectable		 2dyrC-5aoxB:
17.86
2dyrJ-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 8 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.84A 2dyrP-5aoxB:
undetectable
2dyrW-5aoxB:
undetectable		 2dyrP-5aoxB:
17.86
2dyrW-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 7 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.80A 2eikC-5aoxB:
undetectable
2eikJ-5aoxB:
undetectable		 2eikC-5aoxB:
17.86
2eikJ-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 8 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.82A 2eikP-5aoxB:
undetectable
2eikW-5aoxB:
undetectable		 2eikP-5aoxB:
17.86
2eikW-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 8 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.81A 2eilC-5aoxB:
undetectable
2eilJ-5aoxB:
undetectable		 2eilC-5aoxB:
17.86
2eilJ-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 7 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.84A 2eimP-5aoxB:
undetectable
2eimW-5aoxB:
undetectable		 2eimP-5aoxB:
17.86
2eimW-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 6 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.88A 3abkP-5aoxB:
undetectable
3abkW-5aoxB:
undetectable		 3abkP-5aoxB:
17.86
3abkW-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 7 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.90A 3ag2P-5aoxB:
undetectable
3ag2W-5aoxB:
undetectable		 3ag2P-5aoxB:
17.86
3ag2W-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 8 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.84A 3ag4C-5aoxB:
undetectable
3ag4J-5aoxB:
undetectable		 3ag4C-5aoxB:
17.86
3ag4J-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 7 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.81A 3ag4P-5aoxB:
undetectable
3ag4W-5aoxB:
undetectable		 3ag4P-5aoxB:
17.86
3ag4W-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 7 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.85A 3asnC-5aoxB:
undetectable
3asnJ-5aoxB:
undetectable		 3asnC-5aoxB:
17.86
3asnJ-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 7 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.83A 3asnP-5aoxB:
undetectable
3asnW-5aoxB:
undetectable		 3asnP-5aoxB:
17.86
3asnW-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 7 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.82A 3asoP-5aoxB:
undetectable
3asoW-5aoxB:
undetectable		 3asoP-5aoxB:
17.86
3asoW-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 6 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.77A 3wg7C-5aoxB:
undetectable
3wg7J-5aoxB:
undetectable		 3wg7C-5aoxB:
17.86
3wg7J-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 6 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.93A 3wg7P-5aoxB:
undetectable
3wg7W-5aoxB:
undetectable		 3wg7P-5aoxB:
17.86
3wg7W-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 7 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.82A 3x2qC-5aoxB:
undetectable
3x2qJ-5aoxB:
undetectable		 3x2qC-5aoxB:
17.86
3x2qJ-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 7 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.88A 3x2qP-5aoxB:
undetectable
3x2qW-5aoxB:
undetectable		 3x2qP-5aoxB:
17.86
3x2qW-5aoxB:
23.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		3 / 3 TYR B  27
THR B  29
THR B  61
 U  C  24 ( 3.2A)
U  C  26 ( 4.6A)
U  C  24 (-4.2A)
 0.00A 5aoxB-5aoxB:
18.6		 5aoxB-5aoxB:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		3 / 3 TYR B  27
THR B  29
THR B  61
 U  C  24 ( 3.2A)
U  C  26 ( 4.6A)
U  C  24 (-4.2A)
 0.10A 5aoxE-5aoxB:
17.1		 5aoxE-5aoxB:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 7 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.81A 5b1bP-5aoxB:
undetectable
5b1bW-5aoxB:
undetectable		 5b1bP-5aoxB:
17.86
5b1bW-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 5 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.88A 5x19C-5aoxB:
undetectable
5x19J-5aoxB:
undetectable		 5x19C-5aoxB:
17.86
5x19J-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 7 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.79A 5x1fP-5aoxB:
undetectable
5x1fW-5aoxB:
undetectable		 5x1fP-5aoxB:
17.86
5x1fW-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 7 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.86A 5z85C-5aoxB:
undetectable
5z85J-5aoxB:
undetectable		 5z85C-5aoxB:
17.86
5z85J-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 7 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.85A 5zcoC-5aoxB:
undetectable
5zcoJ-5aoxB:
undetectable		 5zcoC-5aoxB:
17.86
5zcoJ-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 7 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.84A 5zcqC-5aoxB:
undetectable
5zcqJ-5aoxB:
undetectable		 5zcqC-5aoxB:
17.86
5zcqJ-5aoxB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5aox SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN
(Homo
sapiens) 		4 / 7 LEU B  86
PHE B  17
LEU B  13
PHE B   9
 None
 0.86A 5zcqP-5aoxB:
undetectable
5zcqW-5aoxB:
undetectable		 5zcqP-5aoxB:
17.86
5zcqW-5aoxB:
23.40