SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5aoy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5aoy ENDONUCLEASE V
(Mus
musculus) 		4 / 8 LEU A  70
VAL A  48
GLY A  49
VAL A 153
 None
 0.91A 2a1oA-5aoyA:
undetectable		 2a1oA-5aoyA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 5aoy ENDONUCLEASE V
(Mus
musculus) 		3 / 3 SER A 216
HIS A 225
ASP A 181
 None
 0.79A 2wa2B-5aoyA:
undetectable		 2wa2B-5aoyA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZTH_A_SAMA305_1
(CATECHOL
O-METHYLTRANSFERASE)		 5aoy ENDONUCLEASE V
(Mus
musculus) 		3 / 3 SER A 243
GLU A 100
ASP A 126
 None
 0.80A 2zthA-5aoyA:
undetectable		 2zthA-5aoyA:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_1
(CATECHOL
O-METHYLTRANSFERASE)		 5aoy ENDONUCLEASE V
(Mus
musculus) 		3 / 3 SER A 243
GLU A 100
ASP A 126
 None
 0.80A 3bwmA-5aoyA:
undetectable		 3bwmA-5aoyA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_1
(COMT PROTEIN)		 5aoy ENDONUCLEASE V
(Mus
musculus) 		3 / 3 SER A 243
GLU A 100
ASP A 126
 None
 0.81A 3bwyA-5aoyA:
undetectable		 3bwyA-5aoyA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P)		 5aoy ENDONUCLEASE V
(Mus
musculus) 		4 / 8 PHE A 136
VAL A  28
ASN A 128
GLY A 129
 None
 0.82A 3hjoB-5aoyA:
undetectable		 3hjoB-5aoyA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P)		 5aoy ENDONUCLEASE V
(Mus
musculus) 		4 / 8 PHE A 136
VAL A  28
VAL A 125
GLY A 129
 None
 0.72A 3hjoB-5aoyA:
undetectable		 3hjoB-5aoyA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KM6_B_EAAB222_1
(GLUTATHIONE
S-TRANSFERASE P)		 5aoy ENDONUCLEASE V
(Mus
musculus) 		5 / 9 PHE A 136
VAL A  28
VAL A 125
ASN A 128
GLY A 129
 None
 0.90A 3km6B-5aoyA:
undetectable		 3km6B-5aoyA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)		 5aoy ENDONUCLEASE V
(Mus
musculus) 		4 / 7 PHE A 136
VAL A  28
ASN A 128
GLY A 129
 None
 0.82A 3kmoB-5aoyA:
undetectable		 3kmoB-5aoyA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5aoy ENDONUCLEASE V
(Mus
musculus) 		4 / 8 THR A 224
GLY A  50
GLY A  49
VAL A  48
 None
 0.84A 4qvvK-5aoyA:
undetectable
4qvvL-5aoyA:
undetectable		 4qvvK-5aoyA:
22.10
4qvvL-5aoyA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 5aoy ENDONUCLEASE V
(Mus
musculus) 		4 / 8 THR A 224
GLY A  50
GLY A  49
VAL A  48
 None
 0.84A 4qvvY-5aoyA:
undetectable
4qvvZ-5aoyA:
undetectable		 4qvvY-5aoyA:
22.10
4qvvZ-5aoyA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 5aoy ENDONUCLEASE V
(Mus
musculus) 		3 / 3 SER A 243
GLU A 100
ASP A 126
 None
 0.77A 4xudA-5aoyA:
undetectable		 4xudA-5aoyA:
23.40