SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5aoz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA2_1
(CYTOCHROME P450 2D6)		 5aoz PUTATIVE
CELLULOSOMAL
SCAFFOLDIN PROTEIN
(Ruminococcus
flavefaciens) 		5 / 11 THR A 460
VAL A 462
VAL A 517
PHE A 409
PHE A 407
 None
 1.29A 3tbgA-5aozA:
undetectable		 3tbgA-5aozA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 5aoz PUTATIVE
CELLULOSOMAL
SCAFFOLDIN PROTEIN
(Ruminococcus
flavefaciens) 		5 / 10 ASP A 443
VAL A 496
ILE A 535
GLY A 533
ILE A 448
 None
 1.01A 6dj2A-5aozA:
undetectable		 6dj2A-5aozA:
16.15