SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ar1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 5ar1 CELL DIVISION
CONTROL PROTEIN 11
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 228
VAL A 234
LEU A 267
VAL A 265
LEU A 220
 None
 0.70A 2aw1A-5ar1A:
undetectable		 2aw1A-5ar1A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_A_QMRA1214_1
(CAPITELLA TELETA
ACHBP)		 5ar1 CELL DIVISION
CONTROL PROTEIN 11
(Saccharomyces
cerevisiae) 		5 / 9 TYR A 140
CYH A 138
ILE A  88
ILE A 106
PHE A 156
 None
 1.41A 4afgA-5ar1A:
undetectable
4afgB-5ar1A:
undetectable		 4afgA-5ar1A:
22.52
4afgB-5ar1A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_B_QMRB1214_1
(CAPITELLA TELETA
ACHBP)		 5ar1 CELL DIVISION
CONTROL PROTEIN 11
(Saccharomyces
cerevisiae) 		5 / 9 ILE A  88
ILE A 106
PHE A 156
TYR A 140
CYH A 138
 None
 1.40A 4afgA-5ar1A:
undetectable
4afgE-5ar1A:
undetectable		 4afgA-5ar1A:
22.52
4afgE-5ar1A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_D_QMRD1214_1
(CAPITELLA TELETA
ACHBP)		 5ar1 CELL DIVISION
CONTROL PROTEIN 11
(Saccharomyces
cerevisiae) 		5 / 9 TYR A 140
CYH A 138
ILE A  88
ILE A 106
PHE A 156
 None
 1.45A 4afgC-5ar1A:
0.0
4afgD-5ar1A:
0.0		 4afgC-5ar1A:
22.52
4afgD-5ar1A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_E_QMRE1214_1
(CAPITELLA TELETA
ACHBP)		 5ar1 CELL DIVISION
CONTROL PROTEIN 11
(Saccharomyces
cerevisiae) 		5 / 9 TYR A 140
CYH A 138
ILE A  88
ILE A 106
PHE A 156
 None
 1.42A 4afgB-5ar1A:
0.0
4afgC-5ar1A:
0.0		 4afgB-5ar1A:
22.52
4afgC-5ar1A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHD_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 5ar1 CELL DIVISION
CONTROL PROTEIN 11
(Saccharomyces
cerevisiae) 		4 / 4 ARG A 221
PHE A 204
ASP A 213
LEU A 272
 None
 1.47A 5uhdC-5ar1A:
undetectable		 5uhdC-5ar1A:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHD_C_RFPC1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 5ar1 CELL DIVISION
CONTROL PROTEIN 11
(Saccharomyces
cerevisiae) 		4 / 4 ARG A 221
PHE A 204
ASP A 213
LEU A 276
 None
 1.44A 5uhdC-5ar1A:
undetectable		 5uhdC-5ar1A:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5ar1 CELL DIVISION
CONTROL PROTEIN 11
(Saccharomyces
cerevisiae) 		5 / 12 TYR A 114
LEU A 287
PHE A 156
THR A  90
VAL A  28
 None
 1.38A 6djzB-5ar1A:
undetectable		 6djzB-5ar1A:
19.43