SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5arm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 5arm CSP3
(Methylosinus
trichosporium) 		3 / 3 PHE A  29
SER A  73
SER A  70
 None
 0.77A 3ufgB-5armA:
undetectable		 3ufgB-5armA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 5arm CSP3
(Methylosinus
trichosporium) 		5 / 10 ALA A  68
LEU A  87
ALA A  91
LEU A  21
ALA A 128
 None
 1.18A 4zbrA-5armA:
undetectable		 4zbrA-5armA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 5arm CSP3
(Methylosinus
trichosporium) 		5 / 12 GLN A  33
ALA A  39
ALA A  37
ASN A  58
CYH A 118
 None
 1.49A 5cxvA-5armA:
undetectable		 5cxvA-5armA:
12.23