SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5auo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 5auo ATPASE INVOLVED IN
CHROMOSOME
PARTITIONING,
PARA/MIND FAMILY,
MRP HOMOLOG
(Thermococcus
kodakarensis) 		4 / 7 VAL B 226
LEU B  35
THR B  39
LEU B  42
 None
ACP  B 301 (-3.9A)
None
None
 0.94A 1jgsA-5auoB:
undetectable		 1jgsA-5auoB:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NR6_A_DIFA501_1
(CYTOCHROME P450 2C5)		 5auo ATPASE INVOLVED IN
CHROMOSOME
PARTITIONING,
PARA/MIND FAMILY,
MRP HOMOLOG
(Thermococcus
kodakarensis) 		5 / 9 GLY B 239
ALA B 238
THR B  39
LEU B  35
LEU B 222
 None
None
None
ACP  B 301 (-3.9A)
ACP  B 301 ( 4.4A)
 1.10A 1nr6A-5auoB:
undetectable		 1nr6A-5auoB:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 5auo ATPASE INVOLVED IN
CHROMOSOME
PARTITIONING,
PARA/MIND FAMILY,
MRP HOMOLOG
(Thermococcus
kodakarensis) 		3 / 3 ASP B 143
ARG B 146
ASP B 112
 None
 0.90A 1vptA-5auoB:
undetectable		 1vptA-5auoB:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 5auo ATPASE INVOLVED IN
CHROMOSOME
PARTITIONING,
PARA/MIND FAMILY,
MRP HOMOLOG
(Thermococcus
kodakarensis) 		5 / 12 VAL B  43
LEU B  40
VAL B  36
VAL B 185
GLY B 246
 None
 0.96A 2cbrA-5auoB:
undetectable		 2cbrA-5auoB:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5auo ATPASE INVOLVED IN
CHROMOSOME
PARTITIONING,
PARA/MIND FAMILY,
MRP HOMOLOG
(Thermococcus
kodakarensis) 		4 / 5 LEU B  56
ALA B 113
ILE B 110
SER B 111
 None
 1.15A 2othA-5auoB:
undetectable		 2othA-5auoB:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)		 5auo ATPASE INVOLVED IN
CHROMOSOME
PARTITIONING,
PARA/MIND FAMILY,
MRP HOMOLOG
(Thermococcus
kodakarensis) 		5 / 12 MET B 133
ILE B 131
LEU B  56
VAL B  18
LEU B  15
 None
 1.09A 3a51C-5auoB:
undetectable		 3a51C-5auoB:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_A_NCAA192_0
(NICOTINAMIDASE)		 5auo ATPASE INVOLVED IN
CHROMOSOME
PARTITIONING,
PARA/MIND FAMILY,
MRP HOMOLOG
(Thermococcus
kodakarensis) 		5 / 11 ASP B 139
PHE B 147
LEU B 114
ILE B 115
SER B 111
 None
 1.39A 3o94A-5auoB:
4.0		 3o94A-5auoB:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_B_NCAB192_0
(NICOTINAMIDASE)		 5auo ATPASE INVOLVED IN
CHROMOSOME
PARTITIONING,
PARA/MIND FAMILY,
MRP HOMOLOG
(Thermococcus
kodakarensis) 		5 / 11 ASP B 139
PHE B 147
LEU B 114
ILE B 115
SER B 111
 None
 1.41A 3o94B-5auoB:
4.2		 3o94B-5auoB:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_C_NCAC192_0
(NICOTINAMIDASE)		 5auo ATPASE INVOLVED IN
CHROMOSOME
PARTITIONING,
PARA/MIND FAMILY,
MRP HOMOLOG
(Thermococcus
kodakarensis) 		5 / 11 ASP B 139
PHE B 147
LEU B 114
ILE B 115
SER B 111
 None
 1.38A 3o94C-5auoB:
3.8		 3o94C-5auoB:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_D_NCAD192_0
(NICOTINAMIDASE)		 5auo ATPASE INVOLVED IN
CHROMOSOME
PARTITIONING,
PARA/MIND FAMILY,
MRP HOMOLOG
(Thermococcus
kodakarensis) 		5 / 11 ASP B 139
PHE B 147
LEU B 114
ILE B 115
SER B 111
 None
 1.39A 3o94D-5auoB:
3.6		 3o94D-5auoB:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 5auo ATPASE INVOLVED IN
CHROMOSOME
PARTITIONING,
PARA/MIND FAMILY,
MRP HOMOLOG
(Thermococcus
kodakarensis) 		6 / 10 VAL B 185
LEU B 154
VAL B 156
LEU B  40
THR B  39
VAL B  24
 None
 1.01A 4e3hA-5auoB:
undetectable		 4e3hA-5auoB:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 5auo ATPASE INVOLVED IN
CHROMOSOME
PARTITIONING,
PARA/MIND FAMILY,
MRP HOMOLOG
(Thermococcus
kodakarensis) 		3 / 3 HIS B  59
GLY B 107
ILE B 110
 None
 0.58A 4k50A-5auoB:
undetectable		 4k50A-5auoB:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 5auo ATPASE INVOLVED IN
CHROMOSOME
PARTITIONING,
PARA/MIND FAMILY,
MRP HOMOLOG
(Thermococcus
kodakarensis) 		3 / 3 HIS B  59
GLY B 107
ILE B 110
 None
 0.57A 4k50I-5auoB:
undetectable		 4k50I-5auoB:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_F_CHDF103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5auo ATPASE INVOLVED IN
CHROMOSOME
PARTITIONING,
PARA/MIND FAMILY,
MRP HOMOLOG
(Thermococcus
kodakarensis) 		5 / 11 ARG B 247
LEU B 248
LEU B  40
GLU B  46
LEU B  44
 None
 1.19A 4wg0F-5auoB:
undetectable
4wg0G-5auoB:
undetectable
4wg0H-5auoB:
undetectable		 4wg0F-5auoB:
5.47
4wg0G-5auoB:
5.47
4wg0H-5auoB:
5.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5auo ATPASE INVOLVED IN
CHROMOSOME
PARTITIONING,
PARA/MIND FAMILY,
MRP HOMOLOG
(Thermococcus
kodakarensis) 		5 / 11 GLU B  46
LEU B  44
LEU B  40
ARG B 247
LEU B 248
 None
 1.13A 4wg0G-5auoB:
undetectable
4wg0H-5auoB:
undetectable
4wg0I-5auoB:
undetectable		 4wg0G-5auoB:
5.47
4wg0H-5auoB:
5.47
4wg0I-5auoB:
5.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_1
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 5auo ATPASE INVOLVED IN
CHROMOSOME
PARTITIONING,
PARA/MIND FAMILY,
MRP HOMOLOG
(Thermococcus
kodakarensis) 		3 / 3 ARG B 247
LYS B 240
GLU B 243
 None
 0.73A 5d0yA-5auoB:
undetectable		 5d0yA-5auoB:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 5auo ATPASE INVOLVED IN
CHROMOSOME
PARTITIONING,
PARA/MIND FAMILY,
MRP HOMOLOG
(Thermococcus
kodakarensis) 		5 / 10 LEU B 154
LEU B  35
LEU B  42
ALA B  41
LEU B  53
 None
ACP  B 301 (-3.9A)
None
None
None
 1.15A 5y7pB-5auoB:
undetectable		 5y7pB-5auoB:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 5auo ATPASE INVOLVED IN
CHROMOSOME
PARTITIONING,
PARA/MIND FAMILY,
MRP HOMOLOG
(Thermococcus
kodakarensis) 		5 / 10 LEU B 154
LEU B  35
LEU B  42
ALA B  41
LEU B  53
 None
ACP  B 301 (-3.9A)
None
None
None
 1.16A 5y7pH-5auoB:
undetectable		 5y7pH-5auoB:
23.26