SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5av7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1G_A_MTXA171_1
(DIHYDROFOLATE
REDUCTASE)		 5av7 LECTIN
(Calystegia
sepium) 		5 / 12 GLU A  73
ILE A  33
LEU A  45
ILE A 102
THR A 106
 None
 1.28A 1d1gA-5av7A:
undetectable		 1d1gA-5av7A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 5av7 LECTIN
(Calystegia
sepium) 		4 / 7 PRO A  11
GLY A  10
LEU A  99
PHE A  90
 None
 0.98A 2vl2B-5av7A:
undetectable		 2vl2B-5av7A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 5av7 LECTIN
(Calystegia
sepium) 		5 / 11 ILE A 102
ILE A  86
GLY A  85
SER A  49
GLY A 134
 None
 1.08A 4ac9B-5av7A:
undetectable
4ac9C-5av7A:
undetectable		 4ac9B-5av7A:
15.25
4ac9C-5av7A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_B_ACTB701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 5av7 LECTIN
(Calystegia
sepium) 		3 / 3 HIS A 111
GLY A  78
ILE A  77
 None
 0.62A 4k50A-5av7A:
undetectable		 4k50A-5av7A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_J_ACTJ701_0
(RNA (33-MER)
RNA POLYMERASE
3D-POL)		 5av7 LECTIN
(Calystegia
sepium) 		3 / 3 HIS A 111
GLY A  78
ILE A  77
 None
 0.63A 4k50I-5av7A:
undetectable		 4k50I-5av7A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5av7 LECTIN
(Calystegia
sepium) 		6 / 12 ILE A  86
PHE A 104
ILE A  33
LEU A  45
ILE A 102
THR A  84
 None
 1.37A 4x5iA-5av7A:
undetectable		 4x5iA-5av7A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5av7 LECTIN
(Calystegia
sepium) 		6 / 12 ILE A  86
PHE A 104
ILE A  33
LEU A  45
ILE A 102
THR A  84
 None
 1.47A 5eajA-5av7A:
undetectable		 5eajA-5av7A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 5av7 LECTIN
(Calystegia
sepium) 		5 / 10 HIS A 111
VAL A  75
LEU A  83
THR A 106
THR A  84
 None
 1.32A 5jn8A-5av7A:
undetectable		 5jn8A-5av7A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 5av7 LECTIN
(Calystegia
sepium) 		5 / 10 HIS A 111
VAL A  75
LEU A  83
THR A 106
THR A  84
 None
 1.35A 5jn9A-5av7A:
undetectable		 5jn9A-5av7A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 5av7 LECTIN
(Calystegia
sepium) 		5 / 10 HIS A 111
VAL A  75
LEU A  83
THR A 106
THR A  84
 None
 1.33A 5jn9D-5av7A:
undetectable		 5jn9D-5av7A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 5av7 LECTIN
(Calystegia
sepium) 		5 / 12 HIS A 111
VAL A  75
LEU A  83
THR A 106
THR A  84
 None
 1.27A 5jnaB-5av7A:
undetectable		 5jnaB-5av7A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 5av7 LECTIN
(Calystegia
sepium) 		5 / 11 HIS A 111
VAL A  75
LEU A  83
THR A 106
THR A  84
 None
 1.31A 5jnaC-5av7A:
undetectable		 5jnaC-5av7A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 5av7 LECTIN
(Calystegia
sepium) 		5 / 12 HIS A 111
VAL A  75
LEU A  83
THR A 106
THR A  84
 None
 1.30A 5jnaD-5av7A:
undetectable		 5jnaD-5av7A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 5av7 LECTIN
(Calystegia
sepium) 		5 / 11 HIS A 111
VAL A  75
LEU A  83
THR A 106
THR A  84
 None
 1.29A 5jncA-5av7A:
undetectable		 5jncA-5av7A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 5av7 LECTIN
(Calystegia
sepium) 		5 / 10 HIS A 111
VAL A  75
LEU A  83
THR A 106
THR A  84
 None
 1.29A 5jncB-5av7A:
undetectable		 5jncB-5av7A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 5av7 LECTIN
(Calystegia
sepium) 		5 / 10 HIS A 111
VAL A  75
LEU A  83
THR A 106
THR A  84
 None
 1.31A 5ku6A-5av7A:
undetectable		 5ku6A-5av7A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 5av7 LECTIN
(Calystegia
sepium) 		5 / 10 HIS A 111
VAL A  75
LEU A  83
THR A 106
THR A  84
 None
 1.29A 5ku6B-5av7A:
undetectable		 5ku6B-5av7A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5av7 LECTIN
(Calystegia
sepium) 		6 / 12 ILE A  86
PHE A 104
ILE A  33
LEU A  45
ILE A 102
THR A  84
 None
 1.49A 5ujxA-5av7A:
undetectable		 5ujxA-5av7A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5av7 LECTIN
(Calystegia
sepium) 		6 / 12 ILE A  86
PHE A 104
ILE A  33
LEU A  45
ILE A 102
THR A  84
 None
 1.49A 5z6kA-5av7A:
undetectable		 5z6kA-5av7A:
21.91