SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5aws'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RV7_B_AB1B1001_1
(PROTEASE)		 5aws SH3-CONTAINING
GRB2-LIKE PROTEIN
3-INTERACTING
PROTEIN 1
(Homo
sapiens) 		5 / 11 ALA A 821
ILE A 583
VAL A 789
LEU A 798
ALA A 680
 None
 1.19A 1rv7A-5awsA:
undetectable
1rv7B-5awsA:
undetectable		 1rv7A-5awsA:
15.22
1rv7B-5awsA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 5aws SH3-CONTAINING
GRB2-LIKE PROTEIN
3-INTERACTING
PROTEIN 1
(Homo
sapiens) 		3 / 3 ALA A 808
VAL A 806
TRP A 646
 None
 0.58A 1tkqA-5awsA:
undetectable		 1tkqA-5awsA:
5.80