SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ay7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5ay7 XYLANASE
(Aegilops
speltoides) 		4 / 7 ILE A  87
GLY A  88
PRO A 150
ASN A 108
 None
 0.97A 1oniG-5ay7A:
0.9
1oniI-5ay7A:
1.0		 1oniG-5ay7A:
16.62
1oniI-5ay7A:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 5ay7 XYLANASE
(Aegilops
speltoides) 		4 / 5 VAL A 308
GLY A 307
TRP A 305
TRP A 297
 None
 1.36A 1tkqB-5ay7A:
undetectable		 1tkqB-5ay7A:
3.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 5ay7 XYLANASE
(Aegilops
speltoides) 		3 / 3 VAL A 299
TRP A 305
TRP A 297
 None
 1.38A 2xdcC-5ay7A:
undetectable
2xdcD-5ay7A:
undetectable		 2xdcC-5ay7A:
3.81
2xdcD-5ay7A:
3.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 5ay7 XYLANASE
(Aegilops
speltoides) 		3 / 3 VAL A 299
TRP A 305
TRP A 297
 None
 1.38A 2y5mA-5ay7A:
undetectable
2y5mB-5ay7A:
undetectable		 2y5mA-5ay7A:
3.81
2y5mB-5ay7A:
3.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 5ay7 XYLANASE
(Aegilops
speltoides) 		3 / 3 VAL A 299
TRP A 305
TRP A 297
 None
 1.37A 2y6nA-5ay7A:
undetectable
2y6nB-5ay7A:
undetectable		 2y6nA-5ay7A:
3.81
2y6nB-5ay7A:
3.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 5ay7 XYLANASE
(Aegilops
speltoides) 		3 / 3 TRP A 297
VAL A 299
TRP A 305
 None
 1.37A 2y6nA-5ay7A:
undetectable
2y6nB-5ay7A:
undetectable		 2y6nA-5ay7A:
3.81
2y6nB-5ay7A:
3.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_A_VDNA1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5ay7 XYLANASE
(Aegilops
speltoides) 		5 / 12 ILE A 206
LEU A 195
ILE A 192
VAL A 235
ILE A 239
 None
 1.13A 3b2rA-5ay7A:
undetectable		 3b2rA-5ay7A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_B_VDNB1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5ay7 XYLANASE
(Aegilops
speltoides) 		5 / 11 ILE A 206
LEU A 195
ILE A 192
VAL A 235
ILE A 239
 None
 1.11A 3b2rB-5ay7A:
undetectable		 3b2rB-5ay7A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 5ay7 XYLANASE
(Aegilops
speltoides) 		4 / 8 PHE A  12
LEU A 241
PHE A 281
LEU A 280
 None
 1.03A 3i45A-5ay7A:
undetectable		 3i45A-5ay7A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5ay7 XYLANASE
(Aegilops
speltoides) 		5 / 12 ILE A 291
LEU A 284
ASP A 183
ALA A 228
VAL A 283
 None
 0.99A 3rukA-5ay7A:
undetectable		 3rukA-5ay7A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_B_017B202_1
(PROTEASE)		 5ay7 XYLANASE
(Aegilops
speltoides) 		4 / 7 PRO A 312
ARG A 247
GLY A 219
PRO A 220
 None
 0.93A 3ucbB-5ay7A:
undetectable		 3ucbB-5ay7A:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 5ay7 XYLANASE
(Aegilops
speltoides) 		3 / 3 VAL A 299
TRP A 305
TRP A 297
 None
 1.43A 3zq8A-5ay7A:
undetectable
3zq8B-5ay7A:
undetectable		 3zq8A-5ay7A:
3.81
3zq8B-5ay7A:
3.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5ay7 XYLANASE
(Aegilops
speltoides) 		5 / 12 LEU A 241
ILE A 291
LEU A 284
ALA A 228
VAL A 283
 None
 0.99A 4nkvB-5ay7A:
undetectable		 4nkvB-5ay7A:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0O_A_URFA303_1
(RRNA N-GLYCOSIDASE)		 5ay7 XYLANASE
(Aegilops
speltoides) 		4 / 5 TYR A 181
ASN A 179
TYR A 178
ILE A 192
 None
 1.33A 4o0oA-5ay7A:
undetectable		 4o0oA-5ay7A:
21.56