SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ayp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 9 GLY A 200
ALA A 194
THR A  57
ILE A 198
THR A 206
 None
 1.24A 1c9sS-5aypA:
undetectable
1c9sT-5aypA:
undetectable		 1c9sS-5aypA:
16.53
1c9sT-5aypA:
16.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		8 / 11 SER A  82
LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.77A 1rqjA-5aypA:
34.1		 1rqjA-5aypA:
43.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		8 / 11 SER A  82
LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.78A 1rqjB-5aypA:
34.0		 1rqjB-5aypA:
43.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 11 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
THR A 184
 None
 0.73A 1yhlA-5aypA:
23.9		 1yhlA-5aypA:
26.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 11 LEU A  83
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.94A 1yhlA-5aypA:
23.9		 1yhlA-5aypA:
26.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 11 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
THR A 184
 None
 0.69A 1yq7A-5aypA:
23.3		 1yq7A-5aypA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 11 LEU A  83
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.85A 1yq7A-5aypA:
23.3		 1yq7A-5aypA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		7 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.83A 1yv5A-5aypA:
23.5		 1yv5A-5aypA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZW5_A_ZOLA901_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 9 ASP A  86
ASP A  92
ARG A  97
GLN A 160
THR A 184
 None
 0.73A 1zw5A-5aypA:
23.6		 1zw5A-5aypA:
26.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZW5_A_ZOLA901_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 9 ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 1.02A 1zw5A-5aypA:
23.6		 1zw5A-5aypA:
26.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_A_ZOLA901_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 9 ASP A  86
ASP A  92
ARG A  97
GLN A 160
THR A 184
 None
 0.69A 2e91A-5aypA:
17.1		 2e91A-5aypA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_A_ZOLA901_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 9 ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.95A 2e91A-5aypA:
17.1		 2e91A-5aypA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_B_ZOLB902_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 9 ASP A  86
ASP A  92
ARG A  97
GLN A 160
THR A 184
 None
 0.83A 2e91B-5aypA:
7.3		 2e91B-5aypA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_B_ZOLB902_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 9 ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 1.06A 2e91B-5aypA:
7.3		 2e91B-5aypA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 11 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
THR A 184
 None
 0.78A 2f8cF-5aypA:
24.4		 2f8cF-5aypA:
26.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 11 LEU A  83
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.98A 2f8cF-5aypA:
24.4		 2f8cF-5aypA:
26.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		7 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.91A 2f8zF-5aypA:
24.4		 2f8zF-5aypA:
26.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 12 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
THR A 184
 None
 0.90A 2f94F-5aypA:
24.2		 2f94F-5aypA:
26.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 12 LEU A  83
ASP A  86
ASP A  92
ARG A  97
LYS A 183
THR A 184
 None
 0.84A 2f94F-5aypA:
24.2		 2f94F-5aypA:
26.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 12 LEU A  83
ASP A  86
ASP A  92
ARG A  97
THR A 184
GLN A 160
 None
 1.46A 2f94F-5aypA:
24.2		 2f94F-5aypA:
26.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
THR A 184
 None
 0.80A 2f9kF-5aypA:
24.3		 2f9kF-5aypA:
26.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 10 LEU A  83
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 1.00A 2f9kF-5aypA:
24.3		 2f9kF-5aypA:
26.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		7 / 9 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.84A 2o1oA-5aypA:
22.6		 2o1oA-5aypA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
THR A 184
 None
 0.77A 2o1oB-5aypA:
23.3		 2o1oB-5aypA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 10 LEU A  83
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.99A 2o1oB-5aypA:
23.3		 2o1oB-5aypA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
 None
 0.94A 2q58A-5aypA:
22.9		 2q58A-5aypA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 10 LEU A  83
ASP A  86
ASP A  92
GLN A 160
THR A 184
 None
 0.81A 2q58A-5aypA:
22.9		 2q58A-5aypA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 10 LEU A  83
ASP A  92
ARG A  97
GLN A 160
LYS A 183
 None
 1.08A 2q58A-5aypA:
22.9		 2q58A-5aypA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 10 LEU A  83
ASP A  92
GLN A 160
LYS A 183
THR A 184
 None
 1.00A 2q58A-5aypA:
22.9		 2q58A-5aypA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QIS_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
 None
 0.82A 2qisA-5aypA:
24.1		 2qisA-5aypA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 9 SER A  56
LEU A 291
ALA A 286
GLY A 217
LEU A 216
 None
 1.09A 2v0mB-5aypA:
1.8		 2v0mB-5aypA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 11 ALA A 123
ALA A  74
VAL A  17
MET A 187
LEU A  55
 None
 1.27A 3bszE-5aypA:
undetectable		 3bszE-5aypA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 9 ASP A  86
ASP A  92
ARG A  97
GLN A 160
THR A 184
 None
 0.74A 3ez3A-5aypA:
22.9		 3ez3A-5aypA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 9 ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.91A 3ez3A-5aypA:
22.9		 3ez3A-5aypA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 9 ASP A  86
ASP A  92
ARG A  97
GLN A 160
THR A 184
 None
 0.77A 3ez3B-5aypA:
22.7		 3ez3B-5aypA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 9 ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.99A 3ez3B-5aypA:
22.7		 3ez3B-5aypA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 9 ASP A  86
ASP A  92
ARG A  97
GLN A 160
THR A 184
 None
 0.71A 3ez3C-5aypA:
23.0		 3ez3C-5aypA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 9 ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.92A 3ez3C-5aypA:
23.0		 3ez3C-5aypA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
THR A 184
 None
 0.76A 3ez3D-5aypA:
22.5		 3ez3D-5aypA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 10 LEU A  83
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.93A 3ez3D-5aypA:
22.5		 3ez3D-5aypA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IBA_A_ZOLA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 10 ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.84A 3ibaA-5aypA:
22.9		 3ibaA-5aypA:
26.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 9 ASP A  86
ASP A  92
ARG A  97
GLN A 160
THR A 184
 None
 0.73A 3ldwA-5aypA:
22.8		 3ldwA-5aypA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 9 ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.90A 3ldwA-5aypA:
22.8		 3ldwA-5aypA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 9 ASP A  86
ASP A  92
ARG A  97
GLN A 160
THR A 184
 None
 0.75A 3ldwB-5aypA:
22.6		 3ldwB-5aypA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 9 ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 1.00A 3ldwB-5aypA:
22.6		 3ldwB-5aypA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 9 ASP A  86
ASP A  92
ARG A  97
GLN A 160
THR A 184
 None
 0.67A 3ldwC-5aypA:
22.8		 3ldwC-5aypA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 9 ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.92A 3ldwC-5aypA:
22.8		 3ldwC-5aypA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 9 ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.90A 3ldwD-5aypA:
22.4		 3ldwD-5aypA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		7 / 11 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.91A 3n45F-5aypA:
24.2		 3n45F-5aypA:
26.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		7 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.94A 3n46F-5aypA:
24.3		 3n46F-5aypA:
26.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		4 / 8 TYR A  24
THR A 128
ARG A 140
LEU A 143
 None
 1.25A 3wipG-5aypA:
undetectable
3wipH-5aypA:
undetectable		 3wipG-5aypA:
19.65
3wipH-5aypA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFA_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 9 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
 None
 0.82A 4kfaA-5aypA:
23.6		 4kfaA-5aypA:
25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		7 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.88A 4kpdA-5aypA:
24.3		 4kpdA-5aypA:
25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPJ_A_210A901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 9 LEU A  83
ASP A  86
ASP A  92
ARG A  97
LYS A 183
THR A 184
 None
 0.89A 4kpjA-5aypA:
23.6		 4kpjA-5aypA:
25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
THR A 184
 None
 0.76A 4kq5A-5aypA:
23.6		 4kq5A-5aypA:
25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 10 LEU A  83
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.98A 4kq5A-5aypA:
23.6		 4kq5A-5aypA:
25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		7 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.85A 4kqsA-5aypA:
24.0		 4kqsA-5aypA:
25.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		3 / 3 ARG A  27
LEU A  28
GLU A  29
 None
 0.75A 4l3gF-5aypA:
undetectable		 4l3gF-5aypA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
THR A 184
 None
 0.76A 4n9uA-5aypA:
24.0		 4n9uA-5aypA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
THR A 184
 None
 1.26A 4n9uA-5aypA:
24.0		 4n9uA-5aypA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 12 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
THR A 184
 None
 0.89A 4ng6A-5aypA:
23.6		 4ng6A-5aypA:
25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 12 LEU A  83
ASP A  86
ASP A  92
ARG A  97
THR A 184
GLN A 160
 None
 1.50A 4ng6A-5aypA:
23.6		 4ng6A-5aypA:
25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		7 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.85A 4nkeA-5aypA:
23.8		 4nkeA-5aypA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 9 LEU A  83
ASP A  86
ASP A  92
ARG A  97
LYS A 183
THR A 184
 None
 0.88A 4nkfA-5aypA:
24.0		 4nkfA-5aypA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		7 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.84A 4nuaA-5aypA:
24.1		 4nuaA-5aypA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 9 LEU A  83
ASP A  86
ASP A  92
ARG A  97
LYS A 183
THR A 184
 None
 0.95A 4oguA-5aypA:
23.9		 4oguA-5aypA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0V_A_ZOLA401_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 9 ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.95A 4p0vA-5aypA:
24.3		 4p0vA-5aypA:
26.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 11 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
THR A 184
 None
 0.81A 4p0wA-5aypA:
24.2		 4p0wA-5aypA:
26.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 11 LEU A  83
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 1.03A 4p0wA-5aypA:
24.2		 4p0wA-5aypA:
26.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q23_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
 None
 0.83A 4q23A-5aypA:
23.8		 4q23A-5aypA:
25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		7 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.82A 4rxdA-5aypA:
22.9		 4rxdA-5aypA:
26.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		7 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.81A 4rxdB-5aypA:
23.4		 4rxdB-5aypA:
26.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		7 / 10 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.81A 4rxdC-5aypA:
23.3		 4rxdC-5aypA:
26.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		6 / 8 SER A  82
ASP A  92
ARG A  97
MET A 156
GLN A 160
LYS A 183
 None
 0.96A 4umjA-5aypA:
35.3		 4umjA-5aypA:
45.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		7 / 8 SER A  82
LEU A  83
ASP A  86
ASP A  92
ARG A  97
MET A 156
GLN A 160
 None
 0.72A 4umjA-5aypA:
35.3		 4umjA-5aypA:
45.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		8 / 9 SER A  82
LEU A  83
ASP A  86
ASP A  92
ARG A  97
MET A 156
GLN A 160
THR A 184
 None
 0.60A 4umjB-5aypA:
35.7		 4umjB-5aypA:
45.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		8 / 9 SER A  82
LEU A  83
ASP A  92
ARG A  97
MET A 156
GLN A 160
LYS A 183
THR A 184
 None
 0.78A 4umjB-5aypA:
35.7		 4umjB-5aypA:
45.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		4 / 6 HIS A  79
GLY A  46
GLU A  76
ARG A  48
 None
 1.12A 4zbqA-5aypA:
3.1		 4zbqA-5aypA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		7 / 12 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.85A 5cg5A-5aypA:
23.6		 5cg5A-5aypA:
26.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		7 / 12 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
LYS A 183
THR A 184
 None
 0.85A 5cg6A-5aypA:
24.2		 5cg6A-5aypA:
26.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 10 ASP A  86
ASP A  87
ASP A  92
ARG A  97
LYS A 183
 None
 0.76A 5eroC-5aypA:
20.5		 5eroC-5aypA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_A_ACTA1231_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		3 / 3 ARG A 146
THR A 206
ASP A 210
 None
 0.81A 5g5gA-5aypA:
undetectable
5g5gB-5aypA:
undetectable		 5g5gA-5aypA:
22.08
5g5gB-5aypA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		4 / 7 ASP A  86
ASP A  92
ARG A  97
GLN A 160
 None
 0.79A 6g31A-5aypA:
20.0		 6g31A-5aypA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_B_ZOLB401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		4 / 6 ASP A  86
ASP A  92
ARG A  97
GLN A 160
 None
 0.81A 6g31B-5aypA:
20.1		 6g31B-5aypA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 7 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
 None
 0.77A 6g31D-5aypA:
19.4		 6g31D-5aypA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_E_ZOLE401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		4 / 4 LEU A  83
ASP A  86
ASP A  92
ARG A  97
 None
 0.65A 6g31E-5aypA:
7.2		 6g31E-5aypA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_F_ZOLF401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		4 / 5 ASP A  86
ASP A  92
ARG A  97
GLN A 160
 None
 0.68A 6g31F-5aypA:
20.0		 6g31F-5aypA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		4 / 7 ASP A  86
ASP A  92
ARG A  97
GLN A 160
 None
 0.77A 6g31G-5aypA:
19.3		 6g31G-5aypA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		4 / 7 ASP A  92
ARG A  97
GLN A 160
LYS A 183
 None
 1.02A 6g31G-5aypA:
19.3		 6g31G-5aypA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		5 / 6 LEU A  83
ASP A  86
ASP A  92
ARG A  97
GLN A 160
 None
 1.04A 6g31J-5aypA:
20.1		 6g31J-5aypA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_K_ZOLK401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 5ayp FARNESYL DIPHOSPHATE
SYNTHASE
(Geobacillus
stearothermophil
us) 		4 / 4 ASP A  86
ASP A  92
ARG A  97
GLN A 160
 None
 0.79A 6g31K-5aypA:
18.9		 6g31K-5aypA:
17.03