SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b01'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 5b01 MOEN5
(Streptomyces
viridosporus) 		5 / 12 LEU A  59
ALA A 157
ALA A 155
VAL A 170
LEU A 120
 None
 1.09A 1cbsA-5b01A:
undetectable		 1cbsA-5b01A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 5b01 MOEN5
(Streptomyces
viridosporus) 		4 / 7 GLU A 175
LEU A 150
VAL A  38
LEU A 238
 None
 0.92A 1hk3A-5b01A:
2.8		 1hk3A-5b01A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 5b01 MOEN5
(Streptomyces
viridosporus) 		4 / 4 LEU A  59
PRO A  39
LEU A  42
ARG A 171
 None
 1.35A 1hrkB-5b01A:
undetectable		 1hrkB-5b01A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)		 5b01 MOEN5
(Streptomyces
viridosporus) 		3 / 3 ASP A  71
GLU A 195
ARG A 129
 None
 0.87A 1wopA-5b01A:
undetectable		 1wopA-5b01A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_B_STRB402_1
(MINERALOCORTICOID
RECEPTOR)		 5b01 MOEN5
(Streptomyces
viridosporus) 		5 / 12 ASN A   8
LEU A  59
ALA A  60
LEU A 150
LEU A  34
 None
 1.24A 2aa6B-5b01A:
undetectable		 2aa6B-5b01A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 5b01 MOEN5
(Streptomyces
viridosporus) 		4 / 7 SER A 143
ARG A 139
LEU A 221
GLU A 220
 None
 1.09A 2cdqB-5b01A:
undetectable		 2cdqB-5b01A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA703_0
(FERROCHELATASE)		 5b01 MOEN5
(Streptomyces
viridosporus) 		4 / 4 LEU A  59
PRO A  39
LEU A  42
ARG A 171
 None
 1.21A 2hrcA-5b01A:
undetectable		 2hrcA-5b01A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 5b01 MOEN5
(Streptomyces
viridosporus) 		4 / 4 LEU A  59
PRO A  39
LEU A  42
ARG A 171
 None
 1.35A 2hrcB-5b01A:
undetectable		 2hrcB-5b01A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5b01 MOEN5
(Streptomyces
viridosporus) 		5 / 12 ASN A   8
LEU A  59
ALA A  60
LEU A 150
LEU A  34
 None
 1.17A 2oaxB-5b01A:
undetectable		 2oaxB-5b01A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 5b01 MOEN5
(Streptomyces
viridosporus) 		5 / 12 ASN A   8
LEU A  59
ALA A  60
LEU A 150
LEU A  34
 None
 1.19A 2oaxD-5b01A:
undetectable		 2oaxD-5b01A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 5b01 MOEN5
(Streptomyces
viridosporus) 		5 / 12 ASN A   8
LEU A  59
ALA A  60
LEU A 150
LEU A  34
 None
 1.19A 2oaxE-5b01A:
2.7		 2oaxE-5b01A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 5b01 MOEN5
(Streptomyces
viridosporus) 		5 / 12 ASN A   8
LEU A  59
ALA A  60
LEU A 150
LEU A  34
 None
 1.18A 2oaxF-5b01A:
undetectable		 2oaxF-5b01A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5b01 MOEN5
(Streptomyces
viridosporus) 		4 / 4 LEU A  59
PRO A  39
LEU A  42
ARG A 171
 None
 1.35A 2pnjB-5b01A:
undetectable		 2pnjB-5b01A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA426_0
(FERROCHELATASE)		 5b01 MOEN5
(Streptomyces
viridosporus) 		4 / 4 LEU A  59
PRO A  39
LEU A  42
ARG A 171
 None
 1.27A 2qd2A-5b01A:
undetectable		 2qd2A-5b01A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5b01 MOEN5
(Streptomyces
viridosporus) 		4 / 4 LEU A  59
PRO A  39
LEU A  42
ARG A 171
 None
 1.15A 3hcoA-5b01A:
undetectable		 3hcoA-5b01A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5b01 MOEN5
(Streptomyces
viridosporus) 		4 / 4 LEU A  59
PRO A  39
LEU A  42
ARG A 171
 None
 1.19A 3hcoB-5b01A:
undetectable		 3hcoB-5b01A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 5b01 MOEN5
(Streptomyces
viridosporus) 		5 / 12 ASN A 193
GLU A 195
ARG A 256
VAL A 214
ASP A 185
 None
 1.46A 3jb3A-5b01A:
undetectable		 3jb3A-5b01A:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_C_AG2C1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 5b01 MOEN5
(Streptomyces
viridosporus) 		4 / 8 HIS A  28
ASP A 189
ASP A  76
ASP A  74
 None
 1.17A 3n2oC-5b01A:
4.8
3n2oD-5b01A:
4.7		 3n2oC-5b01A:
17.72
3n2oD-5b01A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_1
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 5b01 MOEN5
(Streptomyces
viridosporus) 		5 / 12 LEU A 244
LEU A 221
LEU A 218
ALA A 225
ALA A 176
 None
 1.14A 3vw7A-5b01A:
5.1		 3vw7A-5b01A:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5b01 MOEN5
(Streptomyces
viridosporus) 		4 / 5 LEU A  59
PRO A  39
LEU A  42
ARG A 171
 None
 0.95A 4klrA-5b01A:
undetectable		 4klrA-5b01A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5b01 MOEN5
(Streptomyces
viridosporus) 		4 / 5 MET A   1
LEU A   2
PRO A  39
SER A  56
 None
 1.33A 4kmmB-5b01A:
undetectable		 4kmmB-5b01A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 5b01 MOEN5
(Streptomyces
viridosporus) 		5 / 12 GLY A 154
ALA A 157
LEU A  99
ASN A   8
ILE A  63
 None
 1.30A 4pb1A-5b01A:
undetectable		 4pb1A-5b01A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 5b01 MOEN5
(Streptomyces
viridosporus) 		5 / 12 GLY A 154
ALA A 157
LEU A  99
ASN A   8
ILE A  63
 None
 1.25A 4pd5A-5b01A:
1.9		 4pd5A-5b01A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 5b01 MOEN5
(Streptomyces
viridosporus) 		5 / 9 ARG A 171
ALA A 174
LEU A 156
LEU A  42
LEU A 150
 None
 1.21A 5dqfA-5b01A:
2.6		 5dqfA-5b01A:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 5b01 MOEN5
(Streptomyces
viridosporus) 		5 / 10 ASP A 185
ASP A 186
ASP A 189
ASP A  70
ASP A  71
 None
 1.04A 5eroC-5b01A:
13.7		 5eroC-5b01A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 5b01 MOEN5
(Streptomyces
viridosporus) 		5 / 12 THR A 144
GLY A 151
TYR A 145
ILE A 112
ALA A 157
 None
 1.08A 5kvaA-5b01A:
undetectable		 5kvaA-5b01A:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 5b01 MOEN5
(Streptomyces
viridosporus) 		5 / 12 THR A 144
GLY A 151
TYR A 145
ILE A 112
ALA A 157
 None
 1.04A 5kvaB-5b01A:
undetectable		 5kvaB-5b01A:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND3_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5b01 MOEN5
(Streptomyces
viridosporus) 		5 / 12 ASP A  10
LEU A  68
LEU A  32
ALA A  30
ARG A  90
 None
 1.24A 5nd3B-5b01A:
undetectable		 5nd3B-5b01A:
19.23