SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b0h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 5b0h LEUKOCYTE
CELL-DERIVED
CHEMOTAXIN-2
(Homo
sapiens) 		5 / 12 PHE A  52
ILE A  75
VAL A  82
ILE A  87
ILE A  56
 None
 0.68A 1r5lA-5b0hA:
undetectable		 1r5lA-5b0hA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_1
(GAG-POL POLYPROTEIN)		 5b0h LEUKOCYTE
CELL-DERIVED
CHEMOTAXIN-2
(Homo
sapiens) 		5 / 12 GLY A  99
ALA A  50
ILE A  56
GLY A 103
ILE A  96
 None
 0.77A 2b60A-5b0hA:
undetectable		 2b60A-5b0hA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_2
(GAG-POL POLYPROTEIN)		 5b0h LEUKOCYTE
CELL-DERIVED
CHEMOTAXIN-2
(Homo
sapiens) 		5 / 11 GLY A  99
ALA A  50
ILE A  56
GLY A 103
ILE A  96
 None
 0.82A 2b60B-5b0hA:
undetectable		 2b60B-5b0hA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 5b0h LEUKOCYTE
CELL-DERIVED
CHEMOTAXIN-2
(Homo
sapiens) 		5 / 12 GLY A  99
ALA A  50
ILE A  56
GLY A 103
ILE A  96
 None
 0.85A 2hs1A-5b0hA:
undetectable		 2hs1A-5b0hA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 5b0h LEUKOCYTE
CELL-DERIVED
CHEMOTAXIN-2
(Homo
sapiens) 		5 / 12 GLY A  99
ALA A  50
ILE A  56
GLY A 103
ILE A  96
 None
 0.85A 2rkfA-5b0hA:
undetectable		 2rkfA-5b0hA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 5b0h LEUKOCYTE
CELL-DERIVED
CHEMOTAXIN-2
(Homo
sapiens) 		5 / 12 GLY A  99
ALA A  50
ILE A  56
GLY A 103
ILE A  96
 None
 0.84A 2rkgB-5b0hA:
undetectable		 2rkgB-5b0hA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 5b0h LEUKOCYTE
CELL-DERIVED
CHEMOTAXIN-2
(Homo
sapiens) 		4 / 4 GLY A  58
VAL A  73
GLY A  54
THR A  53
 None
 0.77A 3ib2A-5b0hA:
undetectable		 3ib2A-5b0hA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 5b0h LEUKOCYTE
CELL-DERIVED
CHEMOTAXIN-2
(Homo
sapiens) 		5 / 9 GLY A  99
ALA A  50
ILE A  56
GLY A 103
ILE A  96
 None
 0.86A 3nu4B-5b0hA:
undetectable		 3nu4B-5b0hA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_2
(PROTEASE)		 5b0h LEUKOCYTE
CELL-DERIVED
CHEMOTAXIN-2
(Homo
sapiens) 		5 / 11 GLY A  99
ALA A  50
ILE A  56
GLY A 103
ILE A  96
 None
 0.95A 3s45B-5b0hA:
undetectable		 3s45B-5b0hA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_D_NCTD501_1
(CYTOCHROME P450 2A6)		 5b0h LEUKOCYTE
CELL-DERIVED
CHEMOTAXIN-2
(Homo
sapiens) 		4 / 7 ASN A 123
GLY A  37
ILE A  15
LEU A 133
 None
 0.81A 4ejjD-5b0hA:
undetectable		 4ejjD-5b0hA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5b0h LEUKOCYTE
CELL-DERIVED
CHEMOTAXIN-2
(Homo
sapiens) 		5 / 11 ILE A   6
GLY A  99
GLU A 100
GLY A  77
TRP A   3
 None
 1.07A 4jdsB-5b0hA:
undetectable		 4jdsB-5b0hA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 5b0h LEUKOCYTE
CELL-DERIVED
CHEMOTAXIN-2
(Homo
sapiens) 		4 / 6 PRO A  51
ILE A  96
GLY A  99
GLU A 100
 None
 1.06A 6gqiA-5b0hA:
undetectable		 6gqiA-5b0hA:
12.57