SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b0l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Streptomyces
viridosporus;
Sulfolobus
solfataricus) 		5 / 12 LEU A  59
ALA A 157
ALA A 155
VAL A 170
LEU A 120
 None
None
None
None
BNG  A 502 ( 4.6A)
 1.10A 1cbsA-5b0lA:
undetectable		 1cbsA-5b0lA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_2
(ESTROGEN RECEPTOR)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Streptomyces
viridosporus;
Sulfolobus
solfataricus) 		4 / 6 LEU A 254
ASP A 248
MET A 204
LEU A 135
 None
 1.12A 1errB-5b0lA:
undetectable		 1errB-5b0lA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3004_1
(SERUM ALBUMIN)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Streptomyces
viridosporus;
Sulfolobus
solfataricus) 		4 / 7 GLU A 175
LEU A 150
VAL A  38
LEU A 238
 None
BNG  A 501 ( 4.0A)
None
None
 0.90A 1hk3A-5b0lA:
2.3		 1hk3A-5b0lA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_B_STRB402_1
(MINERALOCORTICOID
RECEPTOR)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Streptomyces
viridosporus;
Sulfolobus
solfataricus) 		5 / 12 ASN A   8
LEU A  59
ALA A  60
LEU A 150
LEU A  34
 None
None
None
BNG  A 501 ( 4.0A)
BNG  A 501 (-3.8A)
 1.30A 2aa6B-5b0lA:
undetectable		 2aa6B-5b0lA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA703_0
(FERROCHELATASE)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Sulfolobus
solfataricus;
Streptomyces
viridosporus) 		4 / 4 LEU A  59
PRO A  39
LEU A  42
ARG A 171
 None
 1.24A 2hrcA-5b0lA:
undetectable		 2hrcA-5b0lA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Sulfolobus
solfataricus;
Streptomyces
viridosporus) 		4 / 4 LEU A  59
PRO A  39
LEU A  42
ARG A 171
 None
 1.39A 2hrcB-5b0lA:
undetectable		 2hrcB-5b0lA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Streptomyces
viridosporus;
Sulfolobus
solfataricus) 		5 / 12 ASN A   8
LEU A  59
ALA A  60
LEU A 150
LEU A  34
 None
None
None
BNG  A 501 ( 4.0A)
BNG  A 501 (-3.8A)
 1.25A 2oaxB-5b0lA:
undetectable		 2oaxB-5b0lA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Streptomyces
viridosporus;
Sulfolobus
solfataricus) 		5 / 12 ASN A   8
LEU A  59
ALA A  60
LEU A 150
LEU A  34
 None
None
None
BNG  A 501 ( 4.0A)
BNG  A 501 (-3.8A)
 1.26A 2oaxD-5b0lA:
2.4		 2oaxD-5b0lA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Streptomyces
viridosporus;
Sulfolobus
solfataricus) 		5 / 12 ASN A   8
LEU A  59
ALA A  60
LEU A 150
LEU A  34
 None
None
None
BNG  A 501 ( 4.0A)
BNG  A 501 (-3.8A)
 1.28A 2oaxE-5b0lA:
undetectable		 2oaxE-5b0lA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Streptomyces
viridosporus;
Sulfolobus
solfataricus) 		5 / 12 ASN A   8
LEU A  59
ALA A  60
LEU A 150
LEU A  34
 None
None
None
BNG  A 501 ( 4.0A)
BNG  A 501 (-3.8A)
 1.24A 2oaxF-5b0lA:
undetectable		 2oaxF-5b0lA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA426_0
(FERROCHELATASE)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Sulfolobus
solfataricus;
Streptomyces
viridosporus) 		4 / 4 LEU A  59
PRO A  39
LEU A  42
ARG A 171
 None
 1.35A 2qd2A-5b0lA:
undetectable		 2qd2A-5b0lA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Sulfolobus
solfataricus;
Streptomyces
viridosporus) 		4 / 4 LEU A  59
PRO A  39
LEU A  42
ARG A 171
 None
 1.24A 3hcoA-5b0lA:
undetectable		 3hcoA-5b0lA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Sulfolobus
solfataricus;
Streptomyces
viridosporus) 		4 / 4 LEU A  59
PRO A  39
LEU A  42
ARG A 171
 None
 1.24A 3hcoB-5b0lA:
undetectable		 3hcoB-5b0lA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_B_SAMB301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Sulfolobus
solfataricus;
Streptomyces
viridosporus) 		5 / 12 GLY A 198
ASP A 197
ASP A 185
LEU A 187
ARG A 256
 None
None
BNG  A 502 ( 3.0A)
None
None
 1.25A 3iv6B-5b0lA:
undetectable		 3iv6B-5b0lA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_A_SALA1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Streptomyces
viridosporus;
Sulfolobus
solfataricus) 		5 / 9 LEU A  32
THR A  13
VAL A  16
LEU A  25
ALA A  27
 None
 1.21A 3unaA-5b0lA:
undetectable		 3unaA-5b0lA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNA_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Streptomyces
viridosporus;
Sulfolobus
solfataricus) 		5 / 9 LEU A  32
THR A  13
VAL A  16
LEU A  25
ALA A  27
 None
 1.22A 3unaB-5b0lA:
undetectable		 3unaB-5b0lA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Streptomyces
viridosporus;
Sulfolobus
solfataricus) 		5 / 9 LEU A  32
THR A  13
VAL A  16
LEU A  25
ALA A  27
 None
 1.22A 3uncA-5b0lA:
undetectable		 3uncA-5b0lA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Streptomyces
viridosporus;
Sulfolobus
solfataricus) 		5 / 9 LEU A  32
THR A  13
VAL A  16
LEU A  25
ALA A  27
 None
 1.21A 3uncB-5b0lA:
1.0		 3uncB-5b0lA:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Sulfolobus
solfataricus;
Streptomyces
viridosporus) 		4 / 5 LEU A  59
PRO A  39
LEU A  42
ARG A 171
 None
 1.03A 4klrA-5b0lA:
undetectable		 4klrA-5b0lA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Streptomyces
viridosporus;
Sulfolobus
solfataricus) 		5 / 12 GLY A 154
ALA A 157
LEU A  99
ASN A   8
ILE A  63
 None
 1.35A 4pb1A-5b0lA:
2.4		 4pb1A-5b0lA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Streptomyces
viridosporus;
Sulfolobus
solfataricus) 		4 / 8 ASN A   8
TRP A  45
PHE A  41
GLU A  44
 None
 1.38A 5hqaA-5b0lA:
undetectable		 5hqaA-5b0lA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Streptomyces
viridosporus;
Sulfolobus
solfataricus) 		4 / 7 LEU A  59
THR A  46
THR A  47
LEU A  99
 None
 1.12A 5jq7B-5b0lA:
undetectable		 5jq7B-5b0lA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Sulfolobus
solfataricus;
Streptomyces
viridosporus) 		5 / 12 THR A 144
GLY A 151
TYR A 145
ILE A 112
ALA A 157
 None
 1.13A 5kvaA-5b0lA:
undetectable		 5kvaA-5b0lA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_0
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Sulfolobus
solfataricus;
Streptomyces
viridosporus) 		5 / 12 THR A 144
GLY A 151
TYR A 145
ILE A 112
ALA A 157
 None
 1.09A 5kvaB-5b0lA:
undetectable		 5kvaB-5b0lA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5b0l MOEN5,DNA-BINDING
PROTEIN 7D
(Sulfolobus
solfataricus;
Streptomyces
viridosporus) 		3 / 3 ASP A 197
ARG A 205
ASP A 191
 None
 0.85A 5zvgA-5b0lA:
undetectable		 5zvgA-5b0lA:
21.31