SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b0s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		3 / 3 TRP A 260
TYR A 202
LEU A 204
 None
 1.09A 1kxhA-5b0sA:
undetectable		 1kxhA-5b0sA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		5 / 12 SER A 208
GLY A  99
ASP A  87
PHE A 100
LEU A 215
 None
None
None
None
MAN  A 403 ( 4.8A)
 1.15A 1lhuA-5b0sA:
undetectable		 1lhuA-5b0sA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		4 / 5 PHE A 173
PHE A 127
LEU A 128
PHE A 131
 None
 1.36A 2y69C-5b0sA:
undetectable
2y69J-5b0sA:
undetectable		 2y69C-5b0sA:
18.41
2y69J-5b0sA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		4 / 5 PHE A 173
PHE A 127
LEU A 128
PHE A 131
 None
 1.36A 2y69P-5b0sA:
undetectable
2y69W-5b0sA:
undetectable		 2y69P-5b0sA:
18.41
2y69W-5b0sA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		4 / 5 PHE A 173
PHE A 127
LEU A 128
PHE A 131
 None
 1.36A 3abmC-5b0sA:
undetectable
3abmJ-5b0sA:
undetectable		 3abmC-5b0sA:
18.41
3abmJ-5b0sA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		4 / 5 PHE A 173
PHE A 127
LEU A 128
PHE A 131
 None
 1.34A 3ag3C-5b0sA:
undetectable
3ag3J-5b0sA:
undetectable		 3ag3C-5b0sA:
18.41
3ag3J-5b0sA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_1
(O-METHYLTRANSFERASE)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		4 / 4 ASP A  80
SER A  75
PHE A  76
SER A  93
 None
 1.49A 3i5uA-5b0sA:
undetectable		 3i5uA-5b0sA:
24.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		3 / 3 GLN A 135
PHE A 131
TYR A 178
 None
 0.95A 3ucjB-5b0sA:
undetectable		 3ucjB-5b0sA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		3 / 3 GLN A 135
PHE A 131
TYR A 178
 None
 0.92A 3ucjA-5b0sA:
undetectable		 3ucjA-5b0sA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		4 / 6 GLU A  40
GLY A  39
LEU A  42
TYR A  37
 None
 0.86A 3w9tB-5b0sA:
undetectable		 3w9tB-5b0sA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		4 / 6 GLU A  40
GLY A  39
LEU A  42
TYR A  37
 None
 0.86A 3w9tE-5b0sA:
undetectable		 3w9tE-5b0sA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		4 / 6 GLU A  40
GLY A  39
LEU A  42
TYR A  37
 None
 0.85A 3w9tF-5b0sA:
undetectable		 3w9tF-5b0sA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		4 / 8 SER A  53
SER A  75
ASP A  80
ASP A  79
 None
 1.36A 4qb9D-5b0sA:
undetectable		 4qb9D-5b0sA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		3 / 3 CYH A 339
MET A 341
ASN A   2
 None
 1.37A 5qh8A-5b0sA:
undetectable		 5qh8A-5b0sA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		5 / 12 ASN A  31
LEU A  45
GLY A  32
GLY A  33
VAL A  34
 BMA  A 401 (-3.3A)
None
None
None
None
 1.01A 5uc1B-5b0sA:
undetectable		 5uc1B-5b0sA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		5 / 12 PHE A 228
PHE A 155
ILE A 139
THR A 145
ALA A 184
 None
 1.11A 5vcgA-5b0sA:
undetectable		 5vcgA-5b0sA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_0
(REGULATORY PROTEIN
TETR)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		5 / 12 ALA A 337
GLY A 330
LEU A  45
CYH A 251
PHE A 314
 None
None
None
None
BMA  A 401 (-3.9A)
 1.41A 5vlmF-5b0sA:
undetectable		 5vlmF-5b0sA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		4 / 5 PHE A 173
PHE A 127
LEU A 128
PHE A 131
 None
 1.34A 5wauC-5b0sA:
undetectable
5wauJ-5b0sA:
undetectable		 5wauC-5b0sA:
18.41
5wauJ-5b0sA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		4 / 5 PHE A 173
PHE A 127
LEU A 128
PHE A 131
 None
 1.32A 5wauc-5b0sA:
undetectable
5wauj-5b0sA:
undetectable		 5wauc-5b0sA:
18.41
5wauj-5b0sA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		4 / 5 PHE A 173
PHE A 127
LEU A 128
PHE A 131
 None
 1.33A 5xdqP-5b0sA:
undetectable
5xdqW-5b0sA:
undetectable		 5xdqP-5b0sA:
18.41
5xdqW-5b0sA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_0
(NS3 PROTEASE)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		5 / 12 GLY A 330
ARG A 113
ILE A 319
GLY A 338
PHE A 120
 None
 1.07A 6c2mA-5b0sA:
undetectable		 6c2mA-5b0sA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_0
(NS3 PROTEASE)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		5 / 12 GLY A 330
ARG A 113
ILE A 319
GLY A 338
PHE A 120
 None
 0.97A 6c2mB-5b0sA:
undetectable		 6c2mB-5b0sA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		4 / 7 ARG A 238
TYR A 264
LEU A 280
VAL A 288
 None
 0.99A 6g2pA-5b0sA:
undetectable		 6g2pA-5b0sA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 5b0s LIN0857 PROTEIN
(Listeria
innocua) 		5 / 12 GLY A 245
TYR A 264
PRO A 253
GLU A 241
GLY A 240
 None
 1.41A 6gngA-5b0sA:
undetectable		 6gngA-5b0sA:
20.06