SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b0u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 5b0u OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT
(Oplophorus
gracilirostris) 		4 / 6 ASP A 100
GLY A 101
THR A 103
PRO A 104
 None
 0.67A 1n4fA-5b0uA:
undetectable		 1n4fA-5b0uA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 5b0u OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT
(Oplophorus
gracilirostris) 		4 / 7 VAL A 127
LEU A  97
PHE A 151
LEU A 149
 None
 1.00A 3qeoB-5b0uA:
undetectable		 3qeoB-5b0uA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5b0u OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT
(Oplophorus
gracilirostris) 		5 / 12 LEU A  30
ILE A  76
GLY A  71
VAL A  90
VAL A  80
 None
 0.95A 4nkvA-5b0uA:
undetectable		 4nkvA-5b0uA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5b0u OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT
(Oplophorus
gracilirostris) 		5 / 12 LEU A  30
ILE A  76
GLY A  71
VAL A  90
VAL A  80
 None
 0.93A 4nkvB-5b0uA:
undetectable		 4nkvB-5b0uA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5b0u OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT
(Oplophorus
gracilirostris) 		5 / 12 LEU A  30
ILE A  76
GLY A  71
VAL A  90
VAL A  80
 None
 0.93A 4nkvC-5b0uA:
undetectable		 4nkvC-5b0uA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5b0u OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT
(Oplophorus
gracilirostris) 		5 / 12 LEU A  30
ILE A  76
GLY A  71
VAL A  90
VAL A  80
 None
 0.91A 4nkvD-5b0uA:
undetectable		 4nkvD-5b0uA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5b0u OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT
(Oplophorus
gracilirostris) 		5 / 12 LEU A  30
ILE A  76
GLY A  71
VAL A  90
VAL A  80
 None
 0.87A 4nkxA-5b0uA:
undetectable		 4nkxA-5b0uA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5b0u OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT
(Oplophorus
gracilirostris) 		5 / 12 LEU A  30
ILE A  76
GLY A  71
VAL A  90
VAL A  80
 None
 0.89A 4nkxC-5b0uA:
undetectable		 4nkxC-5b0uA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5b0u OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT
(Oplophorus
gracilirostris) 		5 / 12 LEU A  30
ILE A  76
GLY A  71
VAL A  90
VAL A  80
 None
 0.86A 4nkxD-5b0uA:
undetectable		 4nkxD-5b0uA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V3C_A_AMHA402_1
(QUEUINE
TRNA-RIBOSYLTRANSFER
ASE)		 5b0u OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT
(Oplophorus
gracilirostris) 		5 / 9 TYR A 114
ASP A 108
GLY A  95
ALA A 118
VAL A 127
 None
 1.41A 5v3cA-5b0uA:
undetectable		 5v3cA-5b0uA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 5b0u OPLOPHORUS-LUCIFERIN
2-MONOOXYGENASE
CATALYTIC SUBUNIT
(Oplophorus
gracilirostris) 		4 / 7 SER A  47
THR A 103
ILE A 117
ALA A 118
 None
 0.83A 6ma7A-5b0uA:
undetectable		 6ma7A-5b0uA:
17.86