SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b13'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 5b13 PHYCOERYTHRIN BETA
SUBUNIT
(Palmaria
palmata) 		5 / 11 ALA G 140
LEU G 105
ASP G 170
GLY G 166
ALA G 173
 PUB  G 203 ( 3.9A)
None
None
None
None
 1.13A 1b02A-5b13G:
undetectable		 1b02A-5b13G:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5b13 PHYCOERYTHRIN ALPHA
SUBUNIT
PHYCOERYTHRIN BETA
SUBUNIT
(Palmaria
palmata;
Palmaria
palmata) 		5 / 12 LEU G  24
GLY G  20
ALA A  45
ASN A  94
SER G   6
 None
 1.09A 1eqbA-5b13G:
undetectable		 1eqbA-5b13G:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5b13 PHYCOERYTHRIN ALPHA
SUBUNIT
PHYCOERYTHRIN BETA
SUBUNIT
(Palmaria
palmata;
Palmaria
palmata) 		5 / 12 LEU G  24
GLY G  20
ALA A  45
ASN A  94
SER G   6
 None
 1.10A 1eqbB-5b13G:
undetectable		 1eqbB-5b13G:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5b13 PHYCOERYTHRIN ALPHA
SUBUNIT
PHYCOERYTHRIN BETA
SUBUNIT
(Palmaria
palmata;
Palmaria
palmata) 		5 / 12 LEU G  24
GLY G  20
ALA A  45
ASN A  94
SER G   6
 None
 1.09A 1eqbC-5b13G:
undetectable		 1eqbC-5b13G:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5b13 PHYCOERYTHRIN ALPHA
SUBUNIT
PHYCOERYTHRIN BETA
SUBUNIT
(Palmaria
palmata;
Palmaria
palmata) 		5 / 12 LEU G  24
GLY G  20
ALA A  45
ASN A  94
SER G   6
 None
 1.10A 1eqbD-5b13G:
undetectable		 1eqbD-5b13G:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 5b13 PHYCOERYTHRIN ALPHA
SUBUNIT
(Palmaria
palmata) 		4 / 6 ALA A  50
LYS A  53
ASP A  57
ALA A  58
 CYC  A 201 ( 4.0A)
None
None
None
 0.36A 1iwhA-5b13A:
8.8		 1iwhA-5b13A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 5b13 PHYCOERYTHRIN BETA
SUBUNIT
(Palmaria
palmata) 		3 / 3 SER G  46
ASP G  39
CYH G 158
 None
CYC  G 202 (-3.2A)
CYC  G 202 (-1.7A)
 1.09A 2br4E-5b13G:
undetectable		 2br4E-5b13G:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 5b13 PHYCOERYTHRIN ALPHA
SUBUNIT
PHYCOERYTHRIN BETA
SUBUNIT
(Palmaria
palmata;
Palmaria
palmata) 		4 / 6 ARG G 108
TYR G  95
THR A   8
ALA A  11
 None
 1.45A 2ql8A-5b13G:
undetectable
2ql8B-5b13G:
undetectable		 2ql8A-5b13G:
19.89
2ql8B-5b13G:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5b13 PHYCOERYTHRIN ALPHA
SUBUNIT
(Palmaria
palmata) 		4 / 6 PHE A 131
LEU A  92
VAL A  93
VAL A  52
 None
 1.18A 2zawA-5b13A:
undetectable		 2zawA-5b13A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_1
(CYTOCHROME P450 2R1)		 5b13 PHYCOERYTHRIN ALPHA
SUBUNIT
PHYCOERYTHRIN BETA
SUBUNIT
(Palmaria
palmata;
Palmaria
palmata) 		4 / 5 ASN G  11
ALA G  26
LEU A  38
THR A   6
 None
 0.94A 3dl9A-5b13G:
undetectable		 3dl9A-5b13G:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 5b13 PHYCOERYTHRIN ALPHA
SUBUNIT
(Palmaria
palmata) 		5 / 8 ALA A 155
LEU A 156
GLU A 151
ALA A  40
MET A 144
 None
 1.47A 3r9tA-5b13A:
undetectable		 3r9tA-5b13A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 5b13 PHYCOERYTHRIN ALPHA
SUBUNIT
(Palmaria
palmata) 		3 / 3 ASN A  30
ALA A  34
ARG A  37
 None
 0.89A 3tj7C-5b13A:
undetectable
3tj7D-5b13A:
undetectable		 3tj7C-5b13A:
18.93
3tj7D-5b13A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 5b13 PHYCOERYTHRIN BETA
SUBUNIT
(Palmaria
palmata) 		4 / 5 GLY G 144
SER G 143
ALA G 140
PHE G  43
 CYC  G 202 ( 3.9A)
None
PUB  G 203 ( 3.9A)
None
 1.06A 4m93B-5b13G:
undetectable
4m93C-5b13G:
undetectable		 4m93B-5b13G:
21.00
4m93C-5b13G:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 5b13 PHYCOERYTHRIN ALPHA
SUBUNIT
(Palmaria
palmata) 		4 / 4 THR A   6
GLY A 103
ASP A 106
SER A   3
 None
 1.29A 4rfqA-5b13A:
undetectable		 4rfqA-5b13A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 5b13 PHYCOERYTHRIN ALPHA
SUBUNIT
(Palmaria
palmata) 		4 / 7 GLY A 150
GLN A 147
ARG A  33
ALA A 154
 None
 0.87A 4txnA-5b13A:
undetectable		 4txnA-5b13A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 5b13 PHYCOERYTHRIN ALPHA
SUBUNIT
(Palmaria
palmata) 		4 / 7 GLY A 150
GLN A 147
ARG A  33
ALA A 154
 None
 0.84A 4txnB-5b13A:
undetectable		 4txnB-5b13A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 5b13 PHYCOERYTHRIN ALPHA
SUBUNIT
(Palmaria
palmata) 		4 / 7 GLY A 150
GLN A 147
ARG A  33
ALA A 154
 None
 0.86A 4txnC-5b13A:
undetectable		 4txnC-5b13A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 5b13 PHYCOERYTHRIN ALPHA
SUBUNIT
(Palmaria
palmata) 		4 / 7 GLY A 150
GLN A 147
ARG A  33
ALA A 154
 None
 0.84A 4txnD-5b13A:
undetectable		 4txnD-5b13A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 5b13 PHYCOERYTHRIN BETA
SUBUNIT
(Palmaria
palmata) 		4 / 5 GLY G 100
SER G 103
GLU G 164
ASP G   3
 None
 1.24A 4xueA-5b13G:
undetectable		 4xueA-5b13G:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_B_RBFB201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 5b13 PHYCOERYTHRIN ALPHA
SUBUNIT
PHYCOERYTHRIN BETA
SUBUNIT
(Palmaria
palmata) 		4 / 7 VAL A  52
ARG A  91
TYR G  18
LEU A 105
 None
 1.08A 5umwB-5b13A:
undetectable
5umwE-5b13A:
undetectable		 5umwB-5b13A:
20.25
5umwE-5b13A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 5b13 PHYCOERYTHRIN BETA
SUBUNIT
(Palmaria
palmata) 		4 / 8 ALA G  93
GLY G 166
LEU G 165
ALA G 138
 None
 0.69A 6mdqA-5b13G:
2.2		 6mdqA-5b13G:
18.50