SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b19'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB502_1
(CYTOCHROME P450 2C8)		 5b19 ASPARTATE RACEMASE
(Picrophilus
torridus) 		5 / 10 ILE A 195
ILE A 174
LEU A 121
VAL A 181
ILE A 205
 None
 1.22A 2nnhB-5b19A:
undetectable		 2nnhB-5b19A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5b19 ASPARTATE RACEMASE
(Picrophilus
torridus) 		4 / 8 LEU A 184
ILE A 174
PRO A 146
LEU A 119
 None
 0.86A 5g48A-5b19A:
undetectable		 5g48A-5b19A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 5b19 ASPARTATE RACEMASE
(Picrophilus
torridus) 		5 / 9 MET A  81
SER A  73
LEU A  71
GLU A  72
ILE A  79
 None
 1.39A 6fdyU-5b19A:
undetectable		 6fdyU-5b19A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_B_ACTB207_0
(DUF1778
DOMAIN-CONTAINING
PROTEIN
N-ACETYLTRANSFERASE)		 5b19 ASPARTATE RACEMASE
(Picrophilus
torridus) 		4 / 6 THR A  16
CYH A  83
GLY A  10
ARG A  49
 None
TLA  A 301 (-3.1A)
None
TLA  A 301 (-3.8A)
 1.28A 6gtqB-5b19A:
undetectable
6gtqD-5b19A:
undetectable		 6gtqB-5b19A:
20.09
6gtqD-5b19A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_E_BEZE701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 5b19 ASPARTATE RACEMASE
(Picrophilus
torridus) 		5 / 11 GLY A   6
LEU A  23
ALA A 212
ALA A  82
PHE A  19
 None
 1.47A 6qgbE-5b19A:
undetectable		 6qgbE-5b19A:
14.26