SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b1q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		4 / 5 LEU A 359
LEU A 447
LEU A 454
GLY A 437
 None
 1.01A 1a4lC-5b1qA:
undetectable		 1a4lC-5b1qA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 ALA A  44
ASP A  40
ILE A  38
ILE A  33
ILE A  64
 None
 0.94A 1hxbB-5b1qA:
undetectable		 1hxbB-5b1qA:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_C_DIFC2701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 LEU A 447
VAL A 434
GLY A 437
ALA A 438
SER A 441
 None
 0.91A 1pxxC-5b1qA:
undetectable		 1pxxC-5b1qA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		3 / 3 ASP A 149
LYS A 154
ARG A 157
 None
 1.14A 1ra8A-5b1qA:
undetectable		 1ra8A-5b1qA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 ALA A  44
ASP A  40
ILE A  38
ILE A  33
ILE A  64
 None
 1.01A 1sduB-5b1qA:
undetectable		 1sduB-5b1qA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		4 / 5 ILE A 260
ARG A 254
LEU A 256
ASN A 257
 None
 1.01A 1y0xX-5b1qA:
undetectable		 1y0xX-5b1qA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		4 / 6 SER A 441
ALA A 440
THR A 387
ASN A 384
 None
 1.12A 1yvpB-5b1qA:
undetectable		 1yvpB-5b1qA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_A_ACTA601_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		4 / 7 SER A 441
ALA A 440
THR A 387
ASN A 384
 None
 0.94A 2i91A-5b1qA:
undetectable		 2i91A-5b1qA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_B_ACTB602_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		4 / 7 SER A 441
ALA A 440
THR A 387
ASN A 384
 None
 0.94A 2i91B-5b1qA:
undetectable		 2i91B-5b1qA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		4 / 7 ILE A  88
GLY A  85
ARG A  83
LEU A  63
 None
 0.90A 3bjwF-5b1qA:
undetectable		 3bjwF-5b1qA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_2
(PROTEASE)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 11 ALA A  44
ASP A  40
ILE A  38
ILE A  33
ILE A  64
 None
 0.97A 3ekxB-5b1qA:
undetectable		 3ekxB-5b1qA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_2
(HIV-1 PROTEASE)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 ALA A  44
ASP A  40
ILE A  38
ILE A  33
ILE A  64
 None
 1.13A 3mwsB-5b1qA:
undetectable		 3mwsB-5b1qA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 ALA A  44
ASP A  40
ILE A  38
ILE A  33
ILE A  64
 None
 0.88A 3nduA-5b1qA:
undetectable		 3nduA-5b1qA:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 ALA A  44
ASP A  40
ILE A  38
ILE A  33
ILE A  64
 None
 1.03A 3ndxA-5b1qA:
undetectable		 3ndxA-5b1qA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		6 / 11 ARG A  83
ALA A  44
ASP A  40
ILE A  38
ILE A  33
ILE A  64
 None
 1.46A 3ndxB-5b1qA:
undetectable		 3ndxB-5b1qA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_2
(CYTOCHROME P450 3A4)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		4 / 7 ILE A 327
LEU A  77
THR A 284
THR A  67
 None
 1.13A 3nxuA-5b1qA:
undetectable		 3nxuA-5b1qA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_1
(PROTEASE)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 ALA A  44
ASP A  40
ILE A  38
ILE A  33
ILE A  64
 None
 0.95A 3oxcA-5b1qA:
undetectable		 3oxcA-5b1qA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_3
(PROTEASE)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 ALA A  44
ASP A  40
ILE A  38
ILE A  33
ILE A  64
 None
 1.02A 3oxcB-5b1qA:
undetectable		 3oxcB-5b1qA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		4 / 5 ILE A 159
THR A 162
THR A 161
PHE A 126
 None
 1.23A 3snfA-5b1qA:
undetectable		 3snfA-5b1qA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 ALA A  44
ASP A  40
ILE A  38
ILE A  33
ILE A  64
 None
 0.97A 3tkgA-5b1qA:
undetectable		 3tkgA-5b1qA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 ALA A  44
ASP A  40
ILE A  38
ILE A  33
ILE A  64
 None
 0.97A 3tkgB-5b1qA:
undetectable		 3tkgB-5b1qA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 ALA A  44
ASP A  40
ILE A  38
ILE A  33
ILE A  64
 None
 1.00A 3tkgD-5b1qA:
undetectable		 3tkgD-5b1qA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZD_A_LEVA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		4 / 5 LYS A 346
ILE A 339
VAL A 382
LEU A 358
 None
 1.23A 3wzdA-5b1qA:
undetectable		 3wzdA-5b1qA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 LEU A 359
LEU A 358
ASN A 355
LEU A 354
VAL A 344
 None
 1.39A 3zqtA-5b1qA:
undetectable		 3zqtA-5b1qA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 LEU A 447
VAL A 434
GLY A 437
ALA A 438
SER A 441
 None
 0.91A 4coxD-5b1qA:
undetectable		 4coxD-5b1qA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_ACTA605_0
(SERUM ALBUMIN)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		3 / 3 LYS A 189
LYS A 251
ALA A  55
 None
 1.40A 4ot2A-5b1qA:
1.5		 4ot2A-5b1qA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 LEU A 447
VAL A 434
GLY A 437
ALA A 438
SER A 441
 None
 0.83A 4otyA-5b1qA:
0.8		 4otyA-5b1qA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 LEU A 447
VAL A 434
GLY A 437
ALA A 438
SER A 441
 None
 0.80A 4otyB-5b1qA:
undetectable		 4otyB-5b1qA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 LEU A 447
VAL A 434
GLY A 437
ALA A 438
SER A 441
 None
 0.90A 4rrwD-5b1qA:
undetectable		 4rrwD-5b1qA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 LEU A 447
VAL A 434
GLY A 437
ALA A 438
SER A 441
 None
 0.97A 4rrxA-5b1qA:
1.4		 4rrxA-5b1qA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 LEU A 447
VAL A 434
GLY A 437
ALA A 438
SER A 441
 None
 0.97A 4rrxB-5b1qA:
undetectable		 4rrxB-5b1qA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 LEU A 447
VAL A 434
GLY A 437
ALA A 438
SER A 441
 None
 0.90A 4rrzD-5b1qA:
undetectable		 4rrzD-5b1qA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XNX_A_41XA707_1
(TRANSPORTER)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 11 ALA A 438
VAL A 439
TYR A 436
GLY A 275
SER A 432
 None
 1.16A 4xnxA-5b1qA:
undetectable		 4xnxA-5b1qA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		4 / 7 PHE A 316
PHE A  20
GLY A  85
LEU A  63
 None
 0.82A 4ze3A-5b1qA:
undetectable		 4ze3A-5b1qA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESJ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		4 / 8 PHE A 316
PHE A  20
GLY A  85
LEU A  63
 None
 0.93A 5esjA-5b1qA:
undetectable		 5esjA-5b1qA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESM_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		4 / 7 PHE A 316
PHE A  20
GLY A  85
LEU A  63
 None
 0.93A 5esmA-5b1qA:
undetectable		 5esmA-5b1qA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IFU_B_GBMB801_1
(PROLINE--TRNA LIGASE)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 9 ILE A 311
GLU A 263
ARG A  83
ILE A  88
GLY A  85
 None
 1.31A 5ifuB-5b1qA:
undetectable		 5ifuB-5b1qA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 LEU A 447
VAL A 434
GLY A 437
ALA A 438
SER A 441
 None
 0.93A 5ikqA-5b1qA:
undetectable		 5ikqA-5b1qA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZJ_A_TEPA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		4 / 8 LEU A 209
PHE A 238
MET A 105
ILE A 201
 None
 0.90A 5mzjA-5b1qA:
2.3		 5mzjA-5b1qA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_B_RBFB201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		4 / 7 VAL A  59
ARG A 255
GLU A 252
TRP A 259
 None
 1.19A 5umwB-5b1qA:
undetectable
5umwE-5b1qA:
undetectable		 5umwB-5b1qA:
10.22
5umwE-5b1qA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_2
(CYTOCHROME P450 3A4)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		4 / 7 ILE A 159
LEU A 142
PHE A 109
THR A 222
 None
 1.03A 5vc0A-5b1qA:
undetectable		 5vc0A-5b1qA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_0
(HIV-1 PROTEASE)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 ALA A  44
ASP A  40
ILE A  38
ILE A  33
ILE A  64
 None
 1.13A 6difA-5b1qA:
undetectable		 6difA-5b1qA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		5 / 12 LEU A 122
ILE A 159
PHE A 166
THR A 194
THR A 240
 None
 1.13A 6djzB-5b1qA:
undetectable		 6djzB-5b1qA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 5b1q U14 PROTEIN
(Human
betaherpesvirus
6B) 		4 / 5 GLU A  35
VAL A  36
LEU A  78
THR A 323
 None
 1.13A 6dyoA-5b1qA:
undetectable		 6dyoA-5b1qA:
12.86