SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b1r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 5b1r B-CELL
DIFFERENTIATION
ANTIGEN CD72
(Mus
musculus) 		5 / 12 LEU A 290
LEU A 286
VAL A 280
ALA A 268
ALA A 269
 None
None
None
None
GOL  A 402 (-3.5A)
 0.99A 1n5xA-5b1rA:
undetectable		 1n5xA-5b1rA:
7.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 5b1r B-CELL
DIFFERENTIATION
ANTIGEN CD72
(Mus
musculus) 		5 / 12 LEU A 290
LEU A 286
VAL A 280
ALA A 268
ALA A 269
 None
None
None
None
GOL  A 402 (-3.5A)
 0.99A 1n5xB-5b1rA:
undetectable		 1n5xB-5b1rA:
7.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_A_GLYA73_0
(NONSTRUCTURAL
PROTEIN 1)		 5b1r B-CELL
DIFFERENTIATION
ANTIGEN CD72
(Mus
musculus) 		4 / 5 ALA A 268
GLN A 299
ILE A 298
ARG A 327
 None
GOL  A 402 ( 4.7A)
None
None
 1.12A 2z0aA-5b1rA:
undetectable		 2z0aA-5b1rA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_A_SALA301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 5b1r B-CELL
DIFFERENTIATION
ANTIGEN CD72
(Mus
musculus) 		4 / 8 ARG A 242
VAL A 280
ILE A 298
GLN A 299
 None
None
None
GOL  A 402 ( 4.7A)
 1.05A 3remA-5b1rA:
undetectable		 3remA-5b1rA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3REM_B_SALB301_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 5b1r B-CELL
DIFFERENTIATION
ANTIGEN CD72
(Mus
musculus) 		4 / 8 ARG A 242
VAL A 280
ILE A 298
GLN A 299
 None
None
None
GOL  A 402 ( 4.7A)
 0.98A 3remB-5b1rA:
undetectable		 3remB-5b1rA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 5b1r B-CELL
DIFFERENTIATION
ANTIGEN CD72
(Mus
musculus) 		4 / 7 PRO A 283
TYR A 239
ILE A 237
ILE A 339
 None
 0.92A 5murB-5b1rA:
undetectable		 5murB-5b1rA:
21.26