SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b23'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 5b23 UNCHARACTERIZED
PROTEIN SORTASE B
(Clostridium
perfringens) 		4 / 6 ASN A  99
ILE A 190
ASN A 130
ASN A 123
 None
 1.27A 1h7xD-5b23A:
undetectable		 1h7xD-5b23A:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5b23 UNCHARACTERIZED
PROTEIN SORTASE B
(Clostridium
perfringens) 		4 / 5 ILE A 175
ILE A 190
ILE A 147
LEU A 204
 None
 0.88A 1zgyA-5b23A:
undetectable		 1zgyA-5b23A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5b23 UNCHARACTERIZED
PROTEIN SORTASE B
(Clostridium
perfringens) 		4 / 7 ILE A 226
ILE A 147
LEU A 204
LEU A 186
 None
 0.83A 3adxA-5b23A:
undetectable		 3adxA-5b23A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ4_B_IMNB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5b23 UNCHARACTERIZED
PROTEIN SORTASE B
(Clostridium
perfringens) 		5 / 10 TYR A 134
VAL A  93
ILE A  82
ASN A 130
LEU A 227
 None
 1.13A 4jq4B-5b23A:
undetectable		 4jq4B-5b23A:
25.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5b23 UNCHARACTERIZED
PROTEIN SORTASE B
(Clostridium
perfringens) 		4 / 4 GLY A  96
VAL A 119
PHE A  91
ILE A 117
 None
 1.13A 4xv2B-5b23A:
undetectable		 4xv2B-5b23A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 5b23 UNCHARACTERIZED
PROTEIN SORTASE B
(Clostridium
perfringens) 		3 / 3 HIS A 105
LYS A 109
PHE A 101
 None
 1.37A 5klaA-5b23A:
undetectable		 5klaA-5b23A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA810_0
(UNCHARACTERIZED
PROTEIN)		 5b23 UNCHARACTERIZED
PROTEIN SORTASE B
(Clostridium
perfringens) 		4 / 6 TYR A 179
TYR A 203
GLU A 206
GLN A 207
 None
 1.41A 6d8pA-5b23A:
undetectable		 6d8pA-5b23A:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HCO_A_FY5A1003_0
(ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
2)		 5b23 UNCHARACTERIZED
PROTEIN SORTASE B
(Clostridium
perfringens) 		5 / 11 THR A 231
ASN A 137
PHE A 144
VAL A 133
THR A  87
 None
 1.38A 6hcoA-5b23A:
undetectable
6hcoB-5b23A:
undetectable		 6hcoA-5b23A:
15.85
6hcoB-5b23A:
15.85