SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b26'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_0
(MNMC2)
5b26 PROTEIN SEL-1
HOMOLOG 1

(Mus
musculus)
5 / 12 GLY A 448
GLY A 450
LEU A 454
TYR A 455
ALA A 437
None
1.16A 3vywA-5b26A:
undetectable
3vywA-5b26A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)
5b26 PROTEIN SEL-1
HOMOLOG 1

(Mus
musculus)
5 / 12 GLY A 448
GLY A 450
LEU A 454
TYR A 455
ALA A 437
None
1.20A 3vywB-5b26A:
undetectable
3vywB-5b26A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_0
(MNMC2)
5b26 PROTEIN SEL-1
HOMOLOG 1

(Mus
musculus)
5 / 12 GLY A 448
GLY A 450
LEU A 454
TYR A 455
ALA A 437
None
1.14A 3vywD-5b26A:
undetectable
3vywD-5b26A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_B_SAMB1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)
5b26 PROTEIN SEL-1
HOMOLOG 1

(Mus
musculus)
5 / 12 GLY A 450
SER A 447
LEU A 508
GLY A 513
ASP A 480
None
1.21A 4blvB-5b26A:
undetectable
4blvB-5b26A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_A_CCSA14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)
5b26 PROTEIN SEL-1
HOMOLOG 1

(Mus
musculus)
4 / 6 ASN A 462
LEU A 465
ARG A 457
GLY A 450
None
1.04A 5o4yA-5b26A:
undetectable
5o4yA-5b26A:
4.07