SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5b29'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 PRO A  38
THR A  53
LEU A 115
ARG A 126
TYR A 128
 PLM  A 200 ( 4.9A)
PLM  A 200 ( 4.2A)
None
PLM  A 200 (-3.7A)
PLM  A 200 (-4.8A)
 0.67A 1cbrA-5b29A:
19.3		 1cbrA-5b29A:
40.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 PRO A  38
THR A  53
LEU A 115
ARG A 126
TYR A 128
 PLM  A 200 ( 4.9A)
PLM  A 200 ( 4.2A)
None
PLM  A 200 (-3.7A)
PLM  A 200 (-4.8A)
 0.67A 1cbrB-5b29A:
19.3		 1cbrB-5b29A:
40.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CBS_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE II)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 PRO A  38
THR A  53
LEU A 115
ARG A 126
TYR A 128
 PLM  A 200 ( 4.9A)
PLM  A 200 ( 4.2A)
None
PLM  A 200 (-3.7A)
PLM  A 200 (-4.8A)
 0.75A 1cbsA-5b29A:
19.2		 1cbsA-5b29A:
42.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 VAL A  25
THR A  53
LEU A 115
ARG A 126
TYR A 128
 None
PLM  A 200 ( 4.2A)
None
PLM  A 200 (-3.7A)
PLM  A 200 (-4.8A)
 0.80A 2cbrA-5b29A:
19.3		 2cbrA-5b29A:
40.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FR3_A_REAA300_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
2)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 PRO A  38
THR A  53
LEU A 115
ARG A 126
TYR A 128
 PLM  A 200 ( 4.9A)
PLM  A 200 ( 4.2A)
None
PLM  A 200 (-3.7A)
PLM  A 200 (-4.8A)
 0.81A 2fr3A-5b29A:
19.3		 2fr3A-5b29A:
42.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		9 / 12 VAL A  25
ALA A  33
SER A  55
THR A  60
ALA A  75
ASP A  76
ARG A  78
ARG A 126
TYR A 128
 None
PLM  A 200 ( 3.7A)
PLM  A 200 ( 4.1A)
PLM  A 200 ( 4.8A)
PLM  A 200 ( 4.0A)
PLM  A 200 ( 4.3A)
None
PLM  A 200 (-3.7A)
PLM  A 200 (-4.8A)
 0.68A 2qm9A-5b29A:
24.7		 2qm9A-5b29A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_A_TDZA201_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		6 / 12 VAL A  25
SER A  55
ALA A  75
ASP A  76
CYH A 124
TYR A 128
 None
PLM  A 200 ( 4.1A)
PLM  A 200 ( 4.0A)
PLM  A 200 ( 4.3A)
None
PLM  A 200 (-4.8A)
 1.26A 2qm9A-5b29A:
24.7		 2qm9A-5b29A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_B_TDZB202_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		8 / 12 TYR A  19
VAL A  25
SER A  55
THR A  60
ALA A  75
ARG A  78
ARG A 126
TYR A 128
 None
None
PLM  A 200 ( 4.1A)
PLM  A 200 ( 4.8A)
PLM  A 200 ( 4.0A)
None
PLM  A 200 (-3.7A)
PLM  A 200 (-4.8A)
 0.51A 2qm9B-5b29A:
25.3		 2qm9B-5b29A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_B_TDZB202_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 VAL A  25
SER A  55
ALA A  75
CYH A 124
TYR A 128
 None
PLM  A 200 ( 4.1A)
PLM  A 200 ( 4.0A)
None
PLM  A 200 (-4.8A)
 1.23A 2qm9B-5b29A:
25.3		 2qm9B-5b29A:
62.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QM9_B_TDZB202_2
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 4 MET A  20
PRO A  38
ASP A  76
ARG A 106
 PLM  A 200 ( 4.0A)
PLM  A 200 ( 4.9A)
PLM  A 200 ( 4.3A)
None
 0.54A 2qm9B-5b29A:
25.3		 2qm9B-5b29A:
62.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 7 TYR A  19
LEU A 104
THR A  53
ASP A  76
 None
None
PLM  A 200 ( 4.2A)
PLM  A 200 ( 4.3A)
 1.01A 2zaxA-5b29A:
undetectable		 2zaxA-5b29A:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 7 VAL A  80
SER A  82
HIS A  93
THR A  74
 None
 0.55A 3arrA-5b29A:
undetectable		 3arrA-5b29A:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 7 PHE A   4
LEU A  91
LEU A  66
LEU A  86
 None
 0.71A 3bgdB-5b29A:
undetectable		 3bgdB-5b29A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 7 TYR A  19
LEU A 104
THR A  53
ASP A  76
 None
None
PLM  A 200 ( 4.2A)
PLM  A 200 ( 4.3A)
 1.04A 3fwgB-5b29A:
undetectable		 3fwgB-5b29A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA271_0
(PROTEIN SSM1)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 5 GLY A  89
LYS A  90
GLU A 107
GLY A  88
 None
 0.83A 3onnA-5b29A:
undetectable		 3onnA-5b29A:
21.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		8 / 12 MET A  20
VAL A  25
PRO A  38
ASP A  76
ARG A  78
ARG A 106
ARG A 126
TYR A 128
 PLM  A 200 ( 4.0A)
None
PLM  A 200 ( 4.9A)
PLM  A 200 ( 4.3A)
None
None
PLM  A 200 (-3.7A)
PLM  A 200 (-4.8A)
 0.60A 3p6gA-5b29A:
24.5		 3p6gA-5b29A:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		7 / 12 MET A  20
VAL A  25
PRO A  38
ASP A  76
CYH A 124
ARG A 126
TYR A 128
 PLM  A 200 ( 4.0A)
None
PLM  A 200 ( 4.9A)
PLM  A 200 ( 4.3A)
None
PLM  A 200 (-3.7A)
PLM  A 200 (-4.8A)
 1.14A 3p6gA-5b29A:
24.5		 3p6gA-5b29A:
60.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 7 MET A  20
ASP A  76
ARG A 126
TYR A 128
 PLM  A 200 ( 4.0A)
PLM  A 200 ( 4.3A)
PLM  A 200 (-3.7A)
PLM  A 200 (-4.8A)
 0.44A 3p6hA-5b29A:
24.3		 3p6hA-5b29A:
60.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 8 GLN A  95
PHE A  70
THR A  53
THR A  60
 None
None
PLM  A 200 ( 4.2A)
PLM  A 200 ( 4.8A)
 0.85A 4n16A-5b29A:
undetectable		 4n16A-5b29A:
19.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QZT_A_ACTA202_0
(RETINOL-BINDING
PROTEIN 2)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 6 TYR A  19
GLU A  72
THR A  74
GLN A  95
 None
 0.75A 4qztA-5b29A:
20.9		 4qztA-5b29A:
40.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QZU_C_ACTC202_0
(RETINOL-BINDING
PROTEIN 2)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 6 TYR A  19
GLU A  72
THR A  74
GLN A  95
LEU A 117
 None
 0.75A 4qzuC-5b29A:
21.1		 4qzuC-5b29A:
40.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QZU_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		5 / 12 MET A  20
ALA A  33
THR A  53
LEU A 115
LEU A 117
 PLM  A 200 ( 4.0A)
PLM  A 200 ( 3.7A)
PLM  A 200 ( 4.2A)
None
None
 0.75A 4qzuC-5b29A:
21.1		 4qzuC-5b29A:
40.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		4 / 6 SER A  34
ASP A  76
ARG A  78
GLY A  24
 None
PLM  A 200 ( 4.3A)
None
None
 1.03A 5cdqA-5b29A:
undetectable
5cdqC-5b29A:
undetectable
5cdqD-5b29A:
undetectable		 5cdqA-5b29A:
17.05
5cdqC-5b29A:
17.05
5cdqD-5b29A:
24.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5b29 FATTY ACID-BINDING
PROTEIN, HEART
(Homo
sapiens) 		6 / 12 TYR A  19
VAL A  25
ALA A  33
PRO A  38
SER A  55
LEU A 115
 None
None
PLM  A 200 ( 3.7A)
PLM  A 200 ( 4.9A)
PLM  A 200 ( 4.1A)
None
 0.83A 5hbsA-5b29A:
20.5		 5hbsA-5b29A:
34.07